Hospaq (Cetrimide, Chlorhexidine Gluconate)

Hospaq is used for external antiseptic purposes on intact or compromised skin. It is suitable for use in both healthcare facilities and home environments, providing broad‑spectrum antimicrobial activity.

• Skin antisepsis before minor surgical or invasive procedures.
• Cleaning of superficial wounds, abrasions, and cuts.
• Preparation of catheter insertion sites to reduce microbial colonisation.
• Management of minor burns and skin irritations.
• Pre‑treatment of skin prior to the application of dressings or topical medications.
• Disinfection of skin after exposure to contaminated water or soil.
• Routine cleansing of skin in patients with compromised immunity.

• Cetrimide and chlorhexidine gluconate act as membrane‑active antiseptics. Cetrimide, a quaternary ammonium compound, disrupts the phospholipid bilayer of bacterial cells, increasing permeability and causing leakage of intracellular contents. Chlorhexidine gluconate binds to negatively charged bacterial cell walls, precipitating cytoplasmic proteins and further compromising membrane integrity, leading to rapid cell death across a broad range of Gram‑positive and Gram‑negative organisms and fungi.

Local antiseptics may cause skin reactions; reported adverse events for Hospaq are generally mild but can include more serious responses.

Common

• Mild skin irritation or redness at the application site.
• Transient itching or burning sensation.
• Dryness or peeling of the treated skin.
• Temporary discoloration or hyperpigmentation of the skin.

Serious

• Allergic contact dermatitis with swelling and blistering.
• Severe chemical burns if applied to extensive broken skin.
• Systemic hypersensitivity reactions such as urticaria or anaphylaxis (rare).
• Delayed wound healing associated with excessive antiseptic exposure.

These effects are usually localized and resolve after discontinuation of the product, but monitoring is advised for any worsening signs.

When using Hospaq, certain precautions help minimise the risk of irritation and ensure safe application.

• Apply only to intact or minimally damaged skin; avoid large open wounds.
• Do not use on mucous membranes, eyes, or the inner ear.
• Keep the product away from children; store out of reach.
• Discontinue use and seek medical advice if signs of allergic reaction appear.
• Avoid prolonged contact with dressings that trap moisture.
• Do not combine with other topical antiseptics unless directed by a healthcare professional.
• Use the product as directed; do not exceed the recommended amount.

Hospaq may interact with other topical agents or systemic medications that affect skin integrity or immune response.

Avoid

• Avoid simultaneous application with other antiseptic solutions containing alcohol or iodine, which can increase irritation.
• Do not apply over skin pre‑treated with strong keratolytic agents such as salicylic acid or urea without professional guidance.

Use with caution

• Use with caution when combined with topical corticosteroids, as the steroid may mask early signs of irritation.
• Caution is advised when using on patients receiving systemic antibiotics, to monitor for potential additive antimicrobial effects.
• When used near surgical sites, coordinate with the operating team to prevent interference with wound healing protocols.