Product image of Humulin R 100 [iU]/mL (Insulin human) 100 [iU]/mL INJECTION, SOLUTION supplied by GNH India

Humulin R 100 [iU]/mL

Active Ingredient:
Insulin human
Form:
INJECTION, SOLUTION
Brand:
Humulin R
Origin:
USA

Humulin R 100 [iU]/mL (Insulin human INJECTION, SOLUTION) 100 [iU]/mL

Insulin human, the active ingredient in Humulin R 100 [iU]/mL, is an insulin presented as a 100 IU/mL/injection solution for parenteral use. It is used to help manage type 1 diabetes mellitus and type 2 diabetes mellitus in patients who require insulin therapy.

GNH India supplies Humulin R 100 [iU]/mL as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

Strength

100 [iU]/mL

Pack Size

1 VIAL, MULTI-DOSE in 1 CARTON (0002-0213-01) / 3 mL in 1 VIAL, MULTI-DOSE

Manufacturer / TM Owner

Eli Lilly and Company

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Indications & Clinical Uses

Humulin R contains insulin human, a short-acting insulin used in the management of diabetes mellitus and related hyperglycemia.

  • Type 1 diabetes mellitus: provides exogenous insulin when the body does not produce enough on its own.
  • Type 2 diabetes mellitus: helps improve glycemic control when insulin treatment is required.
  • Hyperglycemia requiring insulin therapy: supports blood glucose reduction under clinician supervision in patients prescribed insulin.

How It Works

  • Insulin human binds to insulin receptors on target tissues and activates intracellular signaling pathways that promote cellular glucose uptake and utilization. It also reduces hepatic glucose production and influences carbohydrate, fat, and protein metabolism. The result is a pharmacologic replacement or supplementation of endogenous insulin activity in patients who need exogenous insulin.

Side Effects

Humulin R can cause adverse reactions related to insulin therapy and injection use.

Common Side Effects

  • Hypoglycemia: the most common and clinically important adverse effect.
  • Injection-site reactions: redness, swelling, itching, or discomfort may occur.
  • Weight gain: may be seen during insulin treatment.
  • Lipodystrophy: repeated injections in the same area can change local fat tissue.

Serious or Rare Side Effects

  • Severe hypoglycemia: can cause confusion, seizure, loss of consciousness, or need for urgent treatment.
  • Hypokalemia: insulin can lower serum potassium.
  • Severe allergic reaction: rare but potentially life-threatening hypersensitivity may occur.

Precautions & Warnings

Humulin R requires careful use because insulin therapy can cause clinically significant adverse effects.

  • Monitor glucose: blood sugar monitoring helps detect hypoglycemia or inadequate control.
  • Watch for hypoglycemia: risk increases if meals are delayed, missed, or intake changes.
  • Use caution with dose changes: adjustments may be needed with illness, activity, or changes in diet.
  • Rotate injection sites: repeated use of one site can contribute to lipodystrophy.
  • Check for allergy: discontinue and seek urgent care if signs of serious hypersensitivity occur.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Humulin R may interact with other medicines that increase or decrease its glucose-lowering effect.

Major Interactions (Avoid)

  • Other glucose-lowering agents: combined use can increase hypoglycemia risk and requires clinician oversight.
  • Alcohol: may worsen or prolong hypoglycemia.

Moderate Interactions (Monitor Closely)

  • Beta-blockers: can mask warning signs of hypoglycemia.
  • Corticosteroids: may reduce insulin effect and increase glucose.
  • Diuretics: some can affect glucose control or potassium balance.
  • ACE inhibitors: may enhance insulin sensitivity in some patients.

Frequently Asked Questions

Humulin R 100 [iU]/mL contains insulin human and is used to help manage diabetes mellitus when insulin treatment is needed. It is a prescription insulin product used in type 1 diabetes and type 2 diabetes under clinician supervision. The specific treatment plan depends on the patient’s glucose needs and the prescriber’s assessment.

Insulin human binds to insulin receptors on cells and triggers signaling pathways that increase glucose uptake and use. It also reduces the liver’s production of glucose. This pharmacologic action helps replace or supplement the body’s own insulin activity in people who require exogenous insulin.

The usual dose is not fixed in the product description because insulin dosing is individualized. A prescriber determines the regimen based on blood glucose readings, diabetes type, food intake, and other clinical factors. Patients should use only the dose and schedule provided by their healthcare professional.

Insulin products are commonly used when insulin therapy is needed during pregnancy, and treatment decisions should be made by a clinician. For breastfeeding, insulin is generally considered compatible with nursing because it is a peptide hormone, but monitoring and dose review may still be needed. The prescriber should guide treatment in both situations.

Submit the enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team then responds with pricing, availability, shipping details, including cold-chain handling where relevant, and the import paperwork.

Humulin R is insulin human, a short-acting insulin used as part of insulin therapy. Compared with longer-acting insulins, it is designed for prandial or general glucose control rather than sustained basal coverage. The best option depends on the patient’s treatment plan, glucose patterns, and prescriber preference.

As an injectable insulin product, it should be stored refrigerated at 2-8°C, protected from light, and not frozen or shaken. Handling should follow the product label and pharmacy instructions. Before use, users should confirm that the solution and packaging remain acceptable for administration.

Humulin R is given by parenteral administration as an injection solution. The exact route, technique, and schedule are determined by the prescriber and the product labeling. Patients should receive training from a healthcare professional on correct handling and administration.

The most important serious risk is severe hypoglycemia, which can cause confusion, loss of consciousness, seizure, or other urgent symptoms. Other serious risks include hypokalemia and rare severe allergic reactions. Patients should know the warning signs and seek urgent medical help if severe symptoms occur.

Humulin R should not be used in people with known hypersensitivity to insulin human or any ingredient in the formulation. It is also inappropriate when insulin therapy has not been prescribed for the individual condition. A clinician should review allergies, prior reactions, and the planned insulin regimen before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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