Product image of Hunogidon 28 (Desogestrel, Ethinylestradiol | Lactose Anhydrous) supplied by GNH India

Hunogidon 28

Active Ingredient:
Desogestrel, Ethinylestradiol | Lactose Anhydrous
Origin:
EU

Hunogidon 28 (Desogestrel, Ethinylestradiol | Lactose Anhydrous)

Hunogidon 28 is a combined oral contraceptive tablet that contains the synthetic hormones desogestrel and ethinylestradiol, formulated with lactose anhydrous as an inactive ingredient. It is marketed in the European Union as a prescription‑only medication for preventing pregnancy, and is taken by mouth in tablet form. Each tablet delivers a fixed dose of the two hormones that work together to inhibit ovulation and create additional barriers to fertilization.

Manufacturer / TM Owner

Gedeon Richter Plc.

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Indications & Clinical Uses

Hunogidon 28 is indicated for women who require reliable hormonal contraception. It may be prescribed as a primary method of birth control for individuals seeking a reversible, non‑sterilizing option.

  • Prevents pregnancy when taken as directed.
  • Provides cycle control and reduces the risk of ovulation‑related disorders.
  • May be used in women with regular menstrual cycles who have no contraindications to estrogen‑containing contraceptives.
  • Can be part of a combined hormonal regimen that includes other estrogen or progestin products under medical supervision.
  • Offers a convenient once‑daily oral dosing schedule.

How It Works

  • Desogestrel is a progestogenic agent that binds to progesterone receptors, suppressing the mid‑cycle surge of luteinizing hormone and thereby inhibiting ovulation. Ethinylestradiol is a synthetic estrogen that provides negative feedback on the hypothalamic‑pituitary axis, reducing follicle‑stimulating hormone release and stabilizing the endometrial lining. Together, the two hormones also thicken cervical mucus, creating a hostile environment for sperm penetration and thus preventing fertilization.

Side Effects

Like all hormonal contraceptives, Hunogidon 28 may cause unwanted effects, most of which are mild and transient in many users.

Common

  • Nausea or mild stomach upset.
  • Headache, including tension‑type pain.
  • Breast tenderness or slight enlargement.
  • Irregular spotting or breakthrough bleeding.

Serious

  • Deep vein thrombosis or pulmonary embolism.
  • Severe hypertension or hypertensive crisis.
  • Allergic reactions such as rash, swelling, or anaphylaxis.

Precautions & Warnings

Before prescribing Hunogidon 28, clinicians should evaluate individual risk factors and contraindications to ensure safe use in each patient carefully.

  • History of thromboembolic disorders, such as deep vein thrombosis or stroke.
  • Uncontrolled hypertension, cardiovascular disease, or smoking over 15 cigarettes per day.
  • Current or past breast cancer, estrogen‑dependent tumors, or liver disease.
  • Known or suspected pregnancy, as the product is not indicated for use during gestation.
  • Use of combined hormonal contraceptives with other estrogen‑containing therapies without medical supervision.

Avoid Interactions

Hunogidon 28 can interact with several medicines, altering its effectiveness or increasing the risk of adverse events for the patient.

Avoid

  • Strong enzyme inducers such as rifampin, carbamazepine, or phenytoin, which may reduce contraceptive efficacy.
  • Antifungal agents like ketoconazole that increase hormone levels and risk of estrogen‑related side effects.
  • St. John’s wort, a herbal supplement known to lower plasma concentrations of oral contraceptives.

Use with caution

  • Anticoagulants (e.g., warfarin) where hormonal changes may affect clotting parameters.
  • Antihypertensive drugs, especially ACE inhibitors or beta‑blockers, requiring blood pressure monitoring.
  • Other hormonal therapies, including hormone replacement or menopausal regimens, to avoid excess estrogen exposure.

Frequently Asked Questions

Hunogidon 28 contains the synthetic progestin desogestrel and the synthetic estrogen ethinylestradiol.

The tablet is taken orally once daily at the same time each day, following the prescribed cycle regimen.

Smoking, especially more than 15 cigarettes per day, increases cardiovascular risk and is generally considered a contraindication for combined estrogen‑progestin contraceptives.

Combined oral contraceptives are usually not recommended while breastfeeding during the first six weeks postpartum because estrogen may reduce milk production.

If a dose is missed, follow the product’s missed‑dose instructions, which typically involve taking the missed tablet as soon as remembered and continuing the pack, or consulting a healthcare professional.

No, Hunogidon 28 does not provide protection against STIs; barrier methods such as condoms should be used for that purpose.

Most antibiotics do not affect hormonal contraceptives, but enzyme‑inducing drugs like rifampin can lower effectiveness and should be discussed with a clinician.

Common side effects include nausea, headache, breast tenderness, and irregular menstrual bleeding.

Serious but rare risks include blood clots, severe hypertension, and allergic reactions; patients should seek medical attention if these occur.

Yes, Hunogidon 28 is classified as a prescription‑only medication throughout the European Union.

A healthcare provider can advise on the appropriate timing to restart Hunogidon 28 after a miscarriage or abortion.

Inform your doctor about any history of blood clots, cardiovascular disease, liver problems, hormone‑sensitive cancers, smoking habits, and any other medications you are taking.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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