Hyalovet Plus (Sodium Hyaluronate)

Hyalovet Plus is used to support ocular surface health in a variety of common eye conditions where additional lubrication is needed.

• Relief of symptoms associated with dry eye disease, such as burning or gritty sensation.
• Adjunctive therapy after ocular surgery to maintain corneal moisture and promote healing.
• Management of transient irritation caused by environmental factors or prolonged screen use.
• Comfort for contact‑lens wearers experiencing dryness or mild discomfort.
• Support for patients with mild to moderate ocular surface inflammation where lubrication is beneficial.

• Sodium hyaluronate is a high‑molecular‑weight glycosaminoglycan that binds large amounts of water, creating a viscoelastic film on the ocular surface. This film reduces shear stress, maintains a stable tear film, and protects the corneal epithelium. By interacting with CD44 receptors on epithelial cells, it supports cellular migration and proliferation, thereby facilitating wound‑healing processes while preserving corneal hydration during preserving corneal hydration.

Adverse reactions to Hyalovet Plus are generally mild, but occasional more serious events have been reported.

Common

• Transient stinging or mild burning sensation at the moment of instillation, usually lasting seconds.
• Temporary blurred vision that typically resolves within a few minutes after dosing.
• Mild conjunctival redness or itching without swelling.
• Slight increase in tear production leading to a brief watery feeling.

Serious

• Allergic conjunctivitis presenting with swelling, intense itching, and possible eyelid edema.
• Corneal epithelial defect or ulceration that may require ophthalmic treatment.
• Persistent ocular inflammation or keratitis that does not improve with standard care.
• Severe eye pain, sudden loss of visual acuity, or other vision‑threatening events (rare).

When using Hyalovet Plus, certain precautions should be observed to ensure safe and effective use.

• Verify that the product is within its expiration date and the container is intact before each use.
• Avoid contact with the tip of the bottle to prevent microbial contamination.
• Do not use if you have a known hypersensitivity to sodium hyaluronate or any excipients.
• If you wear contact lenses, remove them before instillation and wait several minutes before reinserting.
• Discontinue use and seek medical advice if persistent irritation, redness, or visual changes occur.
• Store the eye drops at room temperature, protected from direct sunlight and moisture.

Hyalovet Plus may interact with other ophthalmic products; consider the following guidance.

Avoid

• Simultaneous use of other preservative‑containing eye drops without adequate interval, which can increase ocular irritation.
• Administration of ophthalmic solutions that contain vasoconstrictors immediately before or after Hyalovet Plus, as they may alter tear film dynamics.
• Do not combine with ophthalmic anesthetic agents before surgery, as excessive lubrication may affect corneal assessment.

Use with caution

• Co‑administration with contact‑lens cleaning solutions; rinse lenses thoroughly before re‑insertion.
• Use in patients receiving topical ocular steroids, monitoring for delayed wound healing.
• Combination with anti‑glaucoma eye drops; observe intra‑ocular pressure if needed.
• When used together with anti‑histamine eye drops, monitor for additive drying effects.