Product image of Hydrokortison Evolan (Hydrocortisone) supplied by GNH India

Hydrokortison Evolan

Active Ingredient:
Hydrocortisone
Origin:
EU

Hydrokortison Evolan (Hydrocortisone)

Hydrocortisone, the active ingredient in Hydrokortison Evolan, is a corticosteroid presented as a topical formulation for skin use. It is employed to reduce inflammation and immune responses in various dermatological conditions.
GNH India supplies Hydrokortison Evolan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Evolan Pharma Ab

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Indications & Clinical Uses

Hydrocortisone acts locally on inflammatory skin disorders, providing relief from redness, itching and swelling.

  • Eczema: reduces inflammation and pruritus associated with atopic dermatitis.
  • Dermatitis: alleviates redness and irritation in contact or irritant dermatitis.
  • Psoriasis: helps control plaque formation and scaling.
  • Allergic skin reactions: diminishes swelling and itching caused by allergic contact.

How It Works

  • Hydrocortisone binds to intracellular glucocorticoid receptors, forming a complex that translocates to the nucleus and modulates gene transcription. This action suppresses the production of pro‑inflammatory cytokines, chemokines and enzymes, thereby decreasing vascular permeability, leukocyte infiltration and overall inflammatory response in the skin.

Side Effects

Topical hydrocortisone may cause local and systemic adverse reactions, most of which are dose‑ and duration‑dependent.

Common Side Effects

  • Skin irritation or burning sensation at the application site.
  • Mild itching or dryness.
  • Redness or mild erythema.
  • Folliculitis or acne‑like eruptions.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis) with swelling, hives or difficulty breathing.
  • Skin atrophy or thinning with prolonged use.
  • Secondary bacterial, fungal or viral infection of the treated area.

Precautions & Warnings

When using Hydrokortison Evolan, consider the following safety measures.

  • Apply to affected area only: avoid eyes, mucous membranes and broken skin.
  • Use the minimum effective amount: follow prescriber instructions regarding frequency and duration.
  • Do not use on infected skin without medical advice: risk of worsening infection.
  • Avoid occlusive dressings unless directed: may increase systemic absorption.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Hydrocortisone can interact with other agents that affect skin integrity or systemic corticosteroid levels.

Major Interactions (Avoid)

  • Systemic corticosteroids: may increase overall glucocorticoid exposure.
  • Immunosuppressants: heightened risk of infection when combined.
  • Live vaccines: topical use may reduce vaccine efficacy.

Moderate Interactions (Monitor Closely)

  • Antifungal agents (e.g., ketoconazole): may increase local absorption.
  • Topical NSAIDs: combined use can raise irritation risk.
  • Photosensitizing agents: may augment photosensitivity reactions.

Frequently Asked Questions

Hydrokortison Evolan is a topical hydrocortisone preparation indicated for inflammatory skin disorders such as eczema (atopic dermatitis), various forms of dermatitis, psoriasis and allergic skin reactions. In each case it helps to reduce redness, swelling, itching and other signs of inflammation.

Hydrocortisone binds to intracellular glucocorticoid receptors, forming a complex that enters the cell nucleus and alters gene transcription. This down‑regulates pro‑inflammatory cytokines, chemokines and enzymes, leading to decreased vascular permeability, reduced leukocyte migration and overall suppression of the inflammatory response in the skin.

The prescribed dose of Hydrokortison Evolan is determined by the treating clinician based on the severity and location of the skin condition. Typically, a thin layer is applied to the affected area once or twice daily, but exact frequency, amount and treatment duration should follow the prescriber’s instructions.

Safety data for topical hydrocortisone in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with their healthcare professional.

To request Hydrokortison Evolan, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets. After the enquiry, the sales team will verify trade or institutional credentials and respond with pricing, availability, shipping details (including any cold‑chain requirements) and required import documentation.

Hydrokortison Evolan contains hydrocortisone, a low‑ to medium‑potency corticosteroid. Compared with higher‑potency agents such as clobetasol or betamethasone, it carries a lower risk of skin atrophy and systemic absorption, making it suitable for mild to moderate inflammation and for use on larger body surface areas or on sensitive skin.

Store Hydrokortison Evolan at room temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use to maintain stability.

Hydrokortison Evolan is applied topically. Clean and gently dry the affected skin, then spread a thin layer of the cream or ointment over the lesion. Avoid contact with eyes, mouth, nostrils and broken skin unless directed by a healthcare professional. Wash hands after application.

Serious adverse reactions, although uncommon, include severe allergic responses such as anaphylaxis, marked skin thinning (atrophy) with prolonged use, and secondary bacterial, fungal or viral infections at the application site. Any signs of worsening skin condition, unusual swelling, or systemic symptoms should prompt immediate medical evaluation.

Hydrokortison Evolan should be avoided in individuals with known hypersensitivity to hydrocortisone or any excipients in the formulation. It is also contraindicated on skin infected with viral (e.g., herpes simplex), bacterial or fungal pathogens unless specifically prescribed, and should not be used on extensive broken skin without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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