Product image of Hydromed (Hydrochlorothiazide) supplied by GNH India

Hydromed

Active Ingredient:
Hydrochlorothiazide
Origin:
EU

Hydromed (Hydrochlorothiazide)

Hydrochlorothiazide, the active ingredient in Hydromed, is a thiazide diuretic presented as an oral tablet for oral use. It helps lower blood pressure and reduces excess fluid in conditions such as hypertension, heart‑failure‑related edema, and certain renal disorders.

GNH India supplies Hydromed as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Medilink A/S

1
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Indications & Clinical Uses

Hydrochlorothiazide acts on the renal tubular system to manage fluid‑related conditions and high blood pressure.

  • Hypertension: lowers systolic and diastolic pressure by promoting sodium and water excretion.
  • Edema associated with heart failure: reduces peripheral and pulmonary fluid accumulation.
  • Renal disorders with fluid overload: assists in controlling volume status in chronic kidney disease.

How It Works

  • Hydrochlorothiazide inhibits the Na⁺/Cl⁻ symporter located in the distal convoluted tubule of the nephron. By blocking this transporter, it decreases sodium reabsorption, which leads to increased urinary excretion of sodium and water, thereby reducing extracellular fluid volume and lowering systemic vascular resistance.

Side Effects

Hydrochlorothiazide may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Increased urination: more frequent need to void.
  • Dizziness or light‑headedness, especially on standing.
  • Electrolyte disturbances such as low potassium or sodium.
  • Photosensitivity: heightened skin reaction to sunlight.

Serious or Rare Side Effects

  • Severe allergic reactions, including rash, itching, swelling, or anaphylaxis.
  • Acute gout attacks due to elevated uric acid levels.
  • Pancreatitis or severe abdominal pain.
  • Blood dyscrasias such as leukopenia or thrombocytopenia.

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety measures.

  • Electrolyte monitoring: check serum potassium, sodium, and magnesium regularly.
  • Renal function assessment: evaluate creatinine clearance to adjust dosing.
  • Diabetes caution: monitor blood glucose as thiazides may impair glucose tolerance.
  • Hepatic disease: use with caution in patients with severe liver impairment.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Hydrochlorothiazide can alter the effects of several other medicines.

Major Interactions (Avoid)

  • Lithium: increased risk of lithium toxicity.
  • Cyclosporine: heightened nephrotoxicity.
  • Digoxin: elevated serum digoxin levels.

Moderate Interactions (Monitor Closely)

  • Antidiabetic agents: possible reduction in blood‑glucose control.
  • ACE inhibitors or ARBs: may enhance potassium loss.
  • NSAIDs: can diminish diuretic efficacy and affect renal function.
  • Corticosteroids: may increase sodium retention counteracting the diuretic effect.

Frequently Asked Questions

Hydromed contains hydrochlorothiazide, a thiazide diuretic prescribed to manage hypertension, reduce fluid buildup in heart‑failure‑related edema, and treat fluid overload associated with certain renal disorders. It works by increasing urinary excretion of sodium and water, helping to lower blood pressure and decrease swelling.

Hydrochlorothiazide blocks the Na⁺/Cl⁻ symporter in the distal convoluted tubule of the kidney. This inhibition reduces sodium reabsorption, leading to increased excretion of sodium and water. The resulting decrease in extracellular fluid volume lowers blood pressure and alleviates edema.

The specific dose of Hydromed is determined by the prescribing clinician based on the patient’s medical condition, response to therapy, and renal function. Dosage may be adjusted over time, and patients should follow the prescriber’s instructions without self‑adjusting the amount.

The safety of hydrochlorothiazide in pregnancy and lactation has not been definitively established. It should only be used if the potential benefit justifies any potential risk to the fetus or infant. Pregnant or nursing individuals must discuss alternatives and risks with their healthcare provider.

To request Hydromed, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Hydromed (hydrochlorothiazide) belongs to the thiazide diuretic class, which lowers blood pressure primarily by reducing fluid volume. Compared with ACE inhibitors or calcium‑channel blockers, thiazides are often used as first‑line therapy or in combination regimens, offering a cost‑effective option with a well‑characterized safety profile.

Hydromed should be stored at room temperature, below 25 °C (77 °F). Keep the tablets in the original packaging, protect them from moisture, heat, and direct sunlight to maintain potency throughout the shelf life.

Hydromed is taken orally, usually with a full glass of water. It can be taken with or without food, but patients should follow the prescriber’s guidance regarding timing and whether to take it in the morning to reduce nocturnal urination.

Serious risks include severe electrolyte disturbances (especially low potassium), allergic reactions such as rash or anaphylaxis, acute gout attacks, and rare blood disorders like leukopenia. Patients should seek immediate medical attention if they experience swelling, difficulty breathing, severe rash, or unexplained fatigue.

Hydromed is contraindicated in patients with known hypersensitivity to hydrochlorothiazide or other sulfonamide-derived drugs, severe renal impairment, and anuria. Caution is also advised for individuals with severe hepatic disease, gout, or those taking interacting medications such as lithium or cyclosporine.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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