Product image of Hydromorphon Stada (Hydromorphone Hydrochloride) supplied by GNH India

Hydromorphon Stada

Active Ingredient:
Hydromorphone Hydrochloride
Origin:
EU

Hydromorphon Stada (Hydromorphone Hydrochloride)

Hydromorphone, the active ingredient in Hydromorphon Stada, is an opioid analgesic presented as a oral tablet for oral use. It treats moderate to severe acute pain, post‑operative pain and cancer‑related pain in adult patients.

GNH India supplies Hydromorphon Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stadapharm Gmbh

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Indications & Clinical Uses

Hydromorphon Stada is an opioid analgesic used to manage pain conditions across several clinical pathways.

  • Moderate to severe acute pain: provides rapid analgesia for short‑term painful episodes.
  • Post‑operative pain: reduces discomfort following surgical procedures.
  • Cancer‑related pain: helps control persistent pain in oncology patients.

How It Works

  • Hydromorphone acts as a full agonist at the µ‑opioid receptors in the central nervous system. Binding to these receptors inhibits the release of neurotransmitters involved in pain transmission, decreases neuronal excitability, and raises the pain threshold, resulting in analgesia and sedation.

Side Effects

Hydromorphon Stada may cause a range of adverse reactions that vary in frequency and severity.

Common Side Effects

  • Nausea
  • Constipation
  • Drowsiness
  • Dry mouth
  • Dizziness
  • Sweating

Serious or Rare Side Effects

  • Respiratory depression
  • Severe hypotension
  • Anaphylactic reaction
  • Adrenal insufficiency
  • Seizures
  • Dependence or addiction

Precautions & Warnings

When prescribing or dispensing Hydromorphon Stada, several safety considerations should be observed.

  • Assess pain level: confirm that opioid therapy is appropriate for the patient.
  • Monitor respiratory function: watch for signs of depression, especially after dose initiation.
  • Evaluate renal and hepatic function: adjust therapy if impairment is present.
  • Avoid concomitant CNS depressants: limit use with benzodiazepines or alcohol.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture and light.

Avoid Interactions

Hydromorphon Stada can interact with other medicines, requiring careful review of a patient’s medication list.

Major Interactions (Avoid)

  • Concomitant use with other strong opioids: risk of additive respiratory depression.
  • Benzodiazepines or barbiturates: profound sedation and respiratory compromise.
  • Monoamine oxidase inhibitors (MAOIs): may precipitate severe hypotension.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inhibitors (e.g., ketoconazole): increase hydromorphone plasma levels.
  • CYP3A4 inducers (e.g., rifampin): reduce analgesic effectiveness.
  • Serotonergic agents (e.g., SSRIs): potential for serotonin syndrome.

Frequently Asked Questions

Hydromorphon Stada is prescribed to relieve moderate to severe pain, including acute pain episodes, pain after surgery, and persistent pain associated with cancer. It is an opioid analgesic intended for adult patients when non‑opioid options are insufficient.

Hydromorphone binds strongly to µ‑opioid receptors in the brain and spinal cord. This activation blocks the transmission of pain signals, reduces neuronal excitability, and raises the threshold for pain perception, producing both analgesia and sedation.

The specific dose of Hydromorphon Stada is individualized. A qualified prescriber determines the appropriate strength, frequency, and duration based on the patient’s pain severity, prior opioid exposure, and overall health status.

Safety data for hydromorphone in pregnancy and lactation are limited. Because opioids can affect fetal development and may be excreted in breast milk, the drug is generally avoided unless the potential benefit justifies the potential risk.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Hydromorphone is more potent on a milligram‑per‑milligram basis than morphine, allowing lower doses for equivalent analgesia. It has a shorter half‑life, which may provide more flexible dosing, but both share similar opioid‑related risks and require careful monitoring.

Store the tablets at ambient temperature below 25 °C, in the original container, protected from moisture and direct light. Keep out of reach of children and do not use if the packaging is damaged.

Hydromorphon Stada is taken orally. Swallow the tablet whole with a full glass of water; do not crush, chew, or split unless specifically instructed by a healthcare professional.

The most critical risks include respiratory depression, severe hypotension, profound sedation, dependence or addiction, and rare allergic reactions such as anaphylaxis. Immediate medical attention is required if breathing becomes shallow or the patient experiences extreme drowsiness.

Patients with known hypersensitivity to hydromorphone or any component of the formulation, those with severe respiratory insufficiency, acute or severe asthma, or paralytic ileus should avoid this medication. It is also contraindicated in individuals taking MAO inhibitors within the past 14 days.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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