Product image of Hydromorphone Quintian 10 Mg/Ml (Hydromorphone Hydrochloride) supplied by GNH India

Hydromorphone Quintian 10 Mg/Ml

Active Ingredient:
Hydromorphone Hydrochloride
Origin:
EU

Hydromorphone Quintian 10 Mg/Ml (Hydromorphone Hydrochloride)

Hydromorphone, the active ingredient in Hydromorphone Quintian 10 Mg/mL, is an opioid analgesic presented as a 10 mg/mL sterile injection for intravenous administration. It is indicated for the management of severe, acute and postoperative pain in adult patients when a strong opioid is required.

GNH India supplies Hydromorphone Quintian 10 Mg/mL as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product meets EU quality standards and is distributed under strict regulatory compliance.

Manufacturer / TM Owner

Quintian Pharma Limited

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Indications & Clinical Uses

Hydromorphone is an opioid analgesic used to manage pain that involves the central nervous system.

  • Severe pain: provides potent analgesia for severe pain unresponsive to non‑opioid agents.
  • Acute pain: relieves acute pain episodes such as injury or trauma.
  • Postoperative pain: controls pain following surgical procedures.

How It Works

  • Hydromorphone binds selectively to μ‑opioid receptors in the central nervous system, mimicking endogenous opioids. This activation inhibits the release of excitatory neurotransmitters, reduces neuronal excitability, and alters pain perception pathways, resulting in strong analgesic effects.

Side Effects

Hydromorphone may cause a range of adverse reactions that vary in frequency and severity.

Common Side Effects

  • Nausea
  • Constipation
  • Drowsiness
  • Dizziness

Serious or Rare Side Effects

  • Respiratory depression
  • Severe hypotension
  • Anaphylactic or severe allergic reaction
  • Dependence, tolerance, or addiction

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety measures.

  • Assess respiratory function: monitor breathing before and during treatment.
  • Evaluate renal and hepatic function: adjust use if impairment is present.
  • Avoid in patients with known hypersensitivity to hydromorphone or its excipients.
  • Use caution in elderly patients: increased sensitivity to central nervous system effects.
  • Concomitant CNS depressants: heightened risk of sedation and respiratory depression.
  • Store at controlled room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Hydromorphone can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Other opioids: additive respiratory depression.
  • Central nervous system depressants (e.g., benzodiazepines, barbiturates): increased sedation.
  • Monoamine oxidase inhibitors (MAOIs): risk of severe adverse reactions.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inhibitors (e.g., erythromycin, ketoconazole): may raise hydromorphone levels.
  • Serotonergic agents (e.g., SSRIs, tramadol): potential for serotonin syndrome.

Frequently Asked Questions

Hydromorphone Quintian is an injectable opioid analgesic used to treat severe, acute and postoperative pain in adult patients when a strong, fast‑acting pain reliever is required.

Hydromorphone acts as an agonist at μ‑opioid receptors in the brain and spinal cord. By activating these receptors, it reduces the release of pain‑transmitting neurotransmitters, dampening the perception of pain and producing a potent analgesic effect.

The dose of Hydromorphone Quintian is individualized and must be determined by a qualified prescriber based on the patient’s pain severity, prior opioid exposure, renal and hepatic function, and other clinical factors.

Safety data for hydromorphone in pregnancy and lactation are limited. Because opioids can cause neonatal respiratory depression and may be excreted in breast milk, it is generally avoided unless the benefit outweighs the potential risk.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and required import documentation.

Hydromorphone is approximately five to seven times more potent than morphine on a milligram‑per‑milligram basis, offering stronger analgesia with a smaller volume of injection. Both act on μ‑opioid receptors, but hydromorphone has a slightly shorter onset and duration, which can be advantageous in certain acute‑pain settings.

Store the product at controlled room temperature, below 25 °C, in its original packaging. Protect it from light, moisture and physical damage. Do not freeze or shake the vial before use.

Hydromorphone Quintian is supplied as a sterile solution for intravenous injection. It is administered by a qualified healthcare professional, typically as a slow push or infusion, according to the prescriber’s instructions and institutional protocols.

The most serious risks include respiratory depression, severe hypotension, anaphylactic reactions, and the potential for dependence, tolerance, or addiction. Prompt monitoring of respiratory status and vital signs is essential, especially after dose initiation or escalation.

Hydromorphone is contraindicated in patients with known hypersensitivity to hydromorphone or any component of the formulation, in those who have taken monoamine oxidase inhibitors within the past 14 days, and in individuals with significant respiratory compromise where opioid use is unsafe.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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