Product image of Hydroxia Esseti Farmaceutici (Glutathione Sodium) supplied by GNH India

Hydroxia Esseti Farmaceutici

Active Ingredient:
Glutathione Sodium
Origin:
EU

Hydroxia Esseti Farmaceutici (Glutathione Sodium)

Glutathione Sodium, the active ingredient in Hydroxia Esseti Farmaceutici, is an antioxidant presented as an injectable solution for intramuscular and intravenous use. It helps replenish cellular glutathione levels and supports redox balance in patients with oxidative stress or glutathione deficiency.

GNH India supplies Hydroxia Esseti Farmaceutici as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies, clinics and clinical research facilities worldwide.

Manufacturer / TM Owner

Esseti Farmaceutici S.R.L.

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Indications & Clinical Uses

Hydroxia Esseti Farmaceutici, containing glutathione sodium, is used in clinical settings that require antioxidant support or correction of glutathione deficiency.

  • Glutathione deficiency: restores intracellular glutathione concentrations and improves cellular antioxidant capacity.
  • Oxidative stress conditions: provides systemic antioxidant support to mitigate tissue damage.
  • Liver disorders: adjunct therapy to support hepatic detoxification and protect against oxidative injury.

How It Works

  • Glutathione sodium acts as a key intracellular reducing agent. After administration, it is taken up by cells where it participates in the glutathione redox cycle, directly scavenging reactive oxygen species, regenerating other antioxidants such as vitamins C and E, and facilitating the conjugation and elimination of electrophilic toxins through glutathione‑S‑transferase mediated pathways.

Side Effects

Glutathione sodium injection may be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Injection site pain or erythema: mild discomfort at the site of administration.
  • Nausea or vomiting: transient gastrointestinal upset.
  • Headache: mild to moderate intensity.
  • Dizziness or flushing: transient circulatory sensations.

Serious or Rare Side Effects

  • Anaphylactic reaction: severe hypersensitivity requiring immediate medical intervention.
  • Hemolysis in G6PD‑deficient patients: rapid destruction of red blood cells.
  • Acute renal failure: unexpected decline in kidney function, especially with high‑dose or prolonged therapy.

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety measures.

  • Assess hypersensitivity: review patient allergy history prior to administration.
  • Monitor liver function: check hepatic enzymes during treatment.
  • Avoid in G6PD deficiency: risk of hemolysis warrants contraindication.
  • Use cautiously in renal impairment: adjust infusion rate and monitor renal parameters.
  • Observe during infusion: watch for signs of anaphylaxis or hypotension.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

Avoid Interactions

Glutathione sodium can interact with other agents, requiring attention to potential additive or antagonistic effects.

Major Interactions (Avoid)

  • High‑dose vitamin C: may compete for redox pathways and reduce glutathione efficacy.
  • Concurrent antioxidant therapy: excessive antioxidant load can blunt intended therapeutic effects.

Moderate Interactions (Monitor Closely)

  • Warfarin: monitor INR as glutathione may influence vitamin K metabolism.
  • Diuretics: watch electrolyte balance, especially potassium.
  • ACE inhibitors: observe blood pressure for additive hypotensive effects.

Frequently Asked Questions

Hydroxia Esseti Farmaceutici is an injectable form of glutathione sodium used to replenish depleted glutathione stores, provide systemic antioxidant protection, and support patients with conditions such as glutathione deficiency, oxidative stress‑related disorders, and certain liver diseases where enhanced detoxification is beneficial.

Glutathione sodium supplies the tripeptide glutathione directly to the bloodstream. Once inside cells, glutathione participates in redox reactions, neutralising reactive oxygen species, regenerating other antioxidants, and serving as a co‑factor for detoxifying enzymes that conjugate and eliminate harmful metabolites.

The dosage of Hydroxia Esseti Farmaceutici is determined by the prescribing clinician based on the patient’s condition, weight, renal and hepatic function, and therapeutic goals. Dosing regimens are individualized and should follow the prescriber’s specific instructions.

Safety data for glutathione sodium during pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by the treating physician after a thorough risk‑benefit assessment.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain logistics if needed) and the necessary import documentation.

Glutathione sodium directly replenishes intracellular glutathione, whereas agents like N‑acetylcysteine act as precursors that must be converted before increasing glutathione levels. Hydroxia therefore offers a more immediate boost in antioxidant capacity, but clinical choice depends on the specific indication, patient tolerance, and physician preference.

The product must be stored refrigerated at 2‑8 °C, protected from light, and should never be frozen or shaken vigorously. It should be kept in its original packaging until use to maintain sterility and potency.

Hydroxia Esseti Farmaceutici is administered by a qualified healthcare professional via intramuscular or intravenous injection. The solution is supplied in a sterile vial and should be diluted or used according to the prescriber’s instructions and aseptic technique guidelines.

The most serious adverse events include anaphylactic or severe hypersensitivity reactions, hemolysis in patients with glucose‑6‑phosphate dehydrogenase deficiency, and acute renal failure, particularly with high‑dose or prolonged administration. Immediate medical attention is required if any of these occur.

Patients with a known hypersensitivity to glutathione or any excipients in the formulation, individuals with G6PD deficiency, those with severe renal impairment, and patients who have experienced severe reactions to similar injectable antioxidants should avoid using this product unless a physician determines that benefits outweigh the risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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