Product image of Hydroxizin Omet Pharma (Hydroxyzine Hydrochloride) supplied by GNH India

Hydroxizin Omet Pharma

Active Ingredient:
Hydroxyzine Hydrochloride
Origin:
EU

Hydroxizin Omet Pharma (Hydroxyzine Hydrochloride)

Hydroxyzine, the active ingredient in Hydroxizin Omet Pharma, is an antihistamine presented as an oral dosage form for oral use. It is employed to relieve symptoms of allergic rhinitis, to reduce itching associated with dermatologic conditions, and to provide anxiolytic and sedative effects in appropriate patients.

GNH India supplies Hydroxizin Omet Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides reliable global distribution.

Manufacturer / TM Owner

Omet Pharma Ab

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Indications & Clinical Uses

  • Hydroxyzine is an H1‑receptor antagonist used to manage several allergic and non‑allergic conditions.
  • Allergic rhinitis: reduces nasal congestion, sneezing and itching associated with seasonal or perennial allergies.
  • Pruritus: alleviates itching caused by urticaria, eczema and other dermatologic disorders.
  • Anxiety: provides short‑term relief of anxiety symptoms in patients requiring sedation.
  • Sedation: induces calming effect before medical procedures or for insomnia in selected individuals.

How It Works

  • Hydroxyzine acts as a selective antagonist of peripheral H1 histamine receptors, blocking histamine‑induced vasodilation, increased vascular permeability, and sensory nerve stimulation. This inhibition reduces allergic manifestations and also influences central nervous system pathways, including serotonergic and cholinergic systems, contributing to its anxiolytic and sedative properties.

Side Effects

Hydroxyzine may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Drowsiness
  • Dry mouth
  • Blurred vision
  • Constipation

Serious or Rare Side Effects

  • Cardiac arrhythmia
  • Severe hypotension
  • Stevens‑Johnson syndrome

Precautions & Warnings

When prescribing hydroxyzine, several safety considerations should be observed.

  • Assess patient history: identify hypersensitivity to hydroxyzine or related compounds.
  • Monitor CNS depression: avoid operating machinery or driving while sedated.
  • Caution in elderly: increased risk of falls and anticholinergic effects.
  • Avoid concomitant CNS depressants: limit use with alcohol, opioids, or benzodiazepines.
  • Pregnancy and lactation: use only if clearly needed after risk‑benefit assessment.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture.

Avoid Interactions

Hydroxyzine can interact with other medicines, requiring attention to the level of interaction.

Major Interactions (Avoid)

  • Central nervous system depressants (e.g., alcohol, opioids, benzodiazepines): additive sedation and respiratory depression.
  • Anticholinergic drugs (e.g., diphenhydramine): increased anticholinergic burden.
  • QT‑prolonging agents (e.g., quinidine, sotalol): heightened risk of cardiac arrhythmias.

Moderate Interactions (Monitor Closely)

  • Monoamine oxidase inhibitors: possible enhancement of serotonergic effects.
  • CYP3A4 inhibitors (e.g., erythromycin): may increase hydroxyzine plasma levels.
  • CYP3A4 inducers (e.g., rifampin): may reduce hydroxyzine effectiveness.

Frequently Asked Questions

Hydroxizin Omet Pharma contains hydroxyzine, an H1‑receptor antagonist indicated for relief of allergic rhinitis symptoms, reduction of itching in dermatologic conditions, short‑term management of anxiety, and provision of sedation before medical procedures or for insomnia in selected patients.

Hydroxyzine blocks peripheral H1 histamine receptors, preventing histamine‑mediated allergic responses such as vasodilation and increased vascular permeability. It also influences central serotonergic and cholinergic pathways, which contributes to its anxiolytic and sedative effects.

The appropriate dose is determined by the prescribing clinician based on the patient’s condition, age, weight, and response. Typical adult dosing ranges are described in the product label, but the exact regimen should be individualized by a qualified health professional.

Data on hydroxyzine use in pregnancy and lactation are limited. It should only be used when the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by the prescriber after careful assessment.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Hydroxyzine offers both antihistaminic and central nervous system effects, providing sedation and anxiolysis in addition to allergy relief. Compared with first‑generation antihistamines such as diphenhydramine, hydroxyzine generally has a longer duration of action and may be preferred when a calming effect is also desired.

Store the product at ambient temperature, preferably below 25 °C. Keep it in the original packaging to protect from moisture and light, and ensure the container is tightly closed when not in use.

Hydroxzizin Omet Pharma is taken orally, usually with a glass of water. The tablet should be swallowed whole unless otherwise directed by the prescriber. Dosing times (e.g., with or without food) are specified in the prescribing information.

Serious adverse reactions, although rare, can include cardiac arrhythmias, severe hypotension, and severe skin reactions such as Stevens‑Johnson syndrome. Patients should be instructed to seek immediate medical attention if they experience symptoms such as irregular heartbeat, fainting, or widespread rash.

Hydroxyzine is contraindicated in individuals with known hypersensitivity to hydroxyzine or any component of the formulation. Caution is advised for patients with severe hepatic impairment, prolonged QT interval, or those taking interacting medications that could exacerbate CNS depression.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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