Product image of Hydroxychloroquinesulfaat Cf (Hydroxychloroquine) supplied by GNH India

Hydroxychloroquinesulfaat Cf

Active Ingredient:
Hydroxychloroquine
Origin:
EU

Hydroxychloroquinesulfaat Cf (Hydroxychloroquine)

Hydroxychloroquine, the active ingredient in Hydroxychloroquinesulfaat Cf, is an antimalarial drug presented as a tablet for oral use. It is used to treat malaria, rheumatoid arthritis and systemic lupus erythematosus in adults.

GNH India supplies Hydroxychloroquinesulfaat Cf as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Centrafarm B.V.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Hydroxychloroquine is employed in the management of parasitic infections and autoimmune diseases.

  • Malaria: effective in treating acute uncomplicated malaria caused by susceptible Plasmodium species.
  • Rheumatoid arthritis: reduces disease activity and joint inflammation in adult patients.
  • Systemic lupus erythematosus: helps control disease flares and skin manifestations in adults.

How It Works

  • Hydroxychloroquine inhibits parasite heme polymerization, preventing formation of toxic hemozoin, and raises lysosomal pH in immune cells, which interferes with antigen processing and cytokine production. These actions reduce parasite survival and modulate the immune response, providing therapeutic benefit in both infectious and autoimmune conditions.

Side Effects

Hydroxychloroquine may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea: occasional upset stomach.
  • Headache: mild to moderate intensity.
  • Abdominal pain: intermittent discomfort.
  • Diarrhea: loose stools.
  • Rash: skin redness or itching.
  • Pruritus: generalized itching.

Serious or Rare Side Effects

  • Retinopathy: progressive vision loss requiring ophthalmologic monitoring.
  • Cardiomyopathy: heart muscle dysfunction, potentially leading to heart failure.
  • Severe hypoglycemia: especially in diabetic patients on insulin or sulfonylureas.
  • Blood dyscrasias: including anemia, leukopenia, or thrombocytopenia.
  • Severe skin reactions: such as Stevens‑Johnson syndrome.
  • Neuropsychiatric effects: including mood changes or seizures.

Precautions & Warnings

Before initiating therapy, several safety considerations should be addressed.

  • Pregnancy: safety not established; use only if potential benefit justifies the risk.
  • Retinal monitoring: baseline eye examination and periodic follow‑up are recommended.
  • Cardiac assessment: evaluate ECG in patients with known cardiac disease or risk factors.
  • Blood glucose: monitor diabetic patients closely for hypoglycemia.
  • Drug interactions: review all concomitant medications for potential interactions.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Hydroxychloroquine can interact with several medicines, affecting safety or efficacy.

Major Interactions (Avoid)

  • Azithromycin: combined use may increase QT‑prolongation risk.
  • Other QT‑prolonging agents: avoid co‑administration to prevent cardiac arrhythmias.
  • Strong CYP450 inhibitors (e.g., ketoconazole): may raise hydroxychloroquine plasma levels.
  • Insulin or oral hypoglycemics: may cause severe hypoglycemia.
  • Anticoagulants (e.g., warfarin): may enhance anticoagulant effect.

Moderate Interactions (Monitor Closely)

  • Rifampicin: may reduce hydroxychloroquine exposure, decreasing efficacy.
  • Enzyme‑inducing antiepileptics (e.g., carbamazepine): may lower drug concentrations.
  • Live vaccines: hydroxychloroquine may diminish vaccine efficacy.

Frequently Asked Questions

Hydroxychloroquinesulfaat Cf contains hydroxychloroquine, which is indicated for the treatment of malaria, rheumatoid arthritis, and systemic lupus erythematosus. In each case, the drug helps control disease activity—clearing parasitic infection in malaria and reducing inflammation and immune‑mediated damage in the autoimmune disorders.

Hydroxychloroquine works by two main mechanisms. It interferes with the parasite’s ability to detoxify heme, leading to toxic buildup that kills malaria organisms. In immune cells, it raises lysosomal pH, which disrupts antigen processing and lowers cytokine production, thereby dampening the inflammatory response seen in rheumatoid arthritis and lupus.

The appropriate dose of Hydroxychloroquinesulfaat Cf is determined by the prescribing clinician based on the specific indication, patient weight, renal function, and other clinical factors. Healthcare professionals tailor the regimen to achieve therapeutic goals while minimizing risk, and patients should follow the exact instructions provided by their prescriber.

Safety data for hydroxychloroquine in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss the risks and alternatives with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and the necessary import documentation.

Hydroxychloroquine offers a favorable safety profile compared with some alternative antimalarials and disease‑modifying antirheumatic drugs (DMARDs). Unlike chloroquine, it has a lower risk of retinal toxicity at recommended doses, and compared with biologic DMARDs, it is administered orally and does not require injection or infusion, making it more convenient for many patients.

Hydroxychloroquinesulfaat Cf should be stored at room temperature, below 25 °C, in its original packaging. The container should be kept tightly closed, protected from moisture and direct sunlight to maintain product stability throughout its shelf life.

The product is intended for oral administration. Patients should swallow the tablet whole with a glass of water, preferably with food to reduce gastrointestinal discomfort. The exact timing and frequency are prescribed by the treating physician based on the indication and individual patient factors.

Serious risks include retinal toxicity, which can lead to irreversible vision loss, and cardiac effects such as QT‑interval prolongation or cardiomyopathy. Additionally, severe hypoglycemia, blood dyscrasias, and rare but life‑threatening skin reactions may occur. Regular monitoring and prompt reporting of symptoms are essential to mitigate these risks.

Hydroxychloroquinesulfaat Cf is contraindicated in patients with known hypersensitivity to hydroxychloroquine or related compounds. Individuals with pre‑existing retinal disease, significant cardiac conduction abnormalities, or severe liver or kidney impairment should avoid use unless a specialist determines that benefits outweigh the risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.