Product image of Hydroxyzine Cristers (Hydroxyzine Hydrochloride) supplied by GNH India

Hydroxyzine Cristers

Active Ingredient:
Hydroxyzine Hydrochloride
Origin:
EU

Hydroxyzine Cristers (Hydroxyzine Hydrochloride)

Hydroxyzine, the active ingredient in Hydroxyzine Cristers, is a first‑generation H1 antihistamine presented as an oral tablet for oral use. It is used to relieve allergic symptoms, manage anxiety, and provide sedation before procedures.

GNH India supplies Hydroxyzine Cristers as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Cristers

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Hydroxyzine acts on allergic and anxiety‑related pathways to alleviate symptoms.

  • Allergic rhinitis: reduces nasal congestion, itching and sneezing.
  • Urticaria: diminishes hives and associated itching.
  • Pruritus: provides relief from generalized itching.
  • Anxiety: alleviates tension and nervousness.
  • Sedation before surgical procedures: induces calmness and drowsiness for pre‑operative comfort.

How It Works

  • Hydroxyzine selectively blocks peripheral histamine H1 receptors, preventing histamine‑mediated responses such as vasodilation, increased vascular permeability, and sensory nerve activation. Its anticholinergic activity contributes to drying of secretions, while central nervous system penetration produces sedative and anxiolytic effects through inhibition of neuronal excitability.

Side Effects

Hydroxyzine may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Drowsiness: feeling unusually sleepy or fatigued.
  • Dry mouth: reduced salivation leading to a parched sensation.
  • Blurred vision: temporary difficulty focusing.
  • Constipation: slowed intestinal motility.
  • Headache: mild to moderate head discomfort.
  • Dizziness: sensation of light‑headedness or unsteadiness.

Serious or Rare Side Effects

  • Tachycardia: abnormally rapid heart rate.
  • Severe hypotension: marked drop in blood pressure.
  • Arrhythmia: irregular heart rhythm.
  • Anaphylaxis: life‑threatening allergic reaction.
  • Seizures: uncontrolled electrical activity in the brain.
  • Hepatic dysfunction: abnormal liver enzyme elevations.

Precautions & Warnings

Before using Hydroxyzine, consider the following safety measures.

  • Pregnancy: safety not established; use only if benefit outweighs risk.
  • Elderly patients: increased sensitivity to sedation; start with low dose.
  • Driving or operating machinery: may impair alertness; avoid hazardous tasks.
  • Concomitant CNS depressants: risk of additive sedation; monitor closely.
  • Store at room temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Hydroxyzine can interact with several medication classes.

Major Interactions (Avoid)

  • CNS depressants (e.g., alcohol, benzodiazepines): additive sedation and respiratory depression.
  • Monoamine oxidase inhibitors (MAOIs): risk of severe hypotension and syncope.
  • Anticholinergic agents (e.g., atropine): heightened anticholinergic burden.

Moderate Interactions (Monitor Closely)

  • Antihypertensives: may enhance blood‑pressure‑lowering effects.
  • Theophylline: hydroxyzine can increase plasma theophylline concentrations.
  • CYP3A4 inhibitors: may raise hydroxyzine levels, requiring dose adjustment.

Frequently Asked Questions

Hydroxyzine Cristers is prescribed to treat allergic conditions such as allergic rhinitis and urticaria, to relieve generalized itching (pruritus), to reduce anxiety, and to provide sedation before surgical or diagnostic procedures. It works by blocking histamine receptors and producing calming effects.

Hydroxyzine works by selectively antagonizing peripheral H1 histamine receptors, which prevents histamine‑induced allergic responses. Its ability to cross the blood‑brain barrier also produces anticholinergic and sedative actions, helping to calm anxiety and induce drowsiness when needed.

The exact dose of Hydroxyzine Cristers is determined by the prescribing clinician based on the patient’s age, condition, and response to therapy. Typical adult dosing ranges are established in clinical guidelines, but the prescriber will set the appropriate regimen for each individual.

Safety of hydroxyzine in pregnancy and lactation has not been conclusively established. It should only be used when the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any required import documentation.

Hydroxyzine is a first‑generation antihistamine, offering both antihistaminic and sedative properties, unlike many second‑generation agents such as cetirizine that are non‑sedating. Its broader central nervous system effects make it useful for anxiety and pre‑operative sedation, but also increase the likelihood of drowsiness and anticholinergic side effects.

Hydroxyzine Cristers should be stored at room temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct light, and ensure the container is tightly closed to maintain stability.

Hydroxyzine Cristers is administered orally. The tablet should be swallowed whole with a glass of water, unless otherwise directed by a healthcare professional. It can be taken with or without food, but consistency with meals may help reduce gastrointestinal discomfort.

Serious risks include severe hypotension, tachycardia, arrhythmias, anaphylactic reactions, seizures, and significant hepatic dysfunction. Patients should be monitored for any sudden changes in blood pressure, heart rhythm, breathing difficulty, or signs of allergic reaction, and seek immediate medical attention if these occur.

Hydroxyzine Cristers is contraindicated in individuals with known hypersensitivity to hydroxyzine or any component of the formulation, in patients with severe central nervous system depression, and in newborns or premature infants. Caution is also advised for those with glaucoma, urinary retention, or significant cardiac disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.