Product image of Hydroxyzine Eg (Hydroxyzine Hydrochloride) supplied by GNH India

Hydroxyzine Eg

Active Ingredient:
Hydroxyzine Hydrochloride
Origin:
EU

Hydroxyzine Eg (Hydroxyzine Hydrochloride)

Hydroxyzine Hydrochloride, the active ingredient in Hydroxyzine Eg, is a first-generation antihistamine presented as an oral dosage form for oral use. It is used to manage allergic skin reactions, pruritus, anxiety, sedation and nausea in appropriate patients.

GNH India supplies Hydroxyzine Eg as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Eg Labo Laboratoires Eurogenerics

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Indications & Clinical Uses

  • Hydroxyzine Hydrochloride is a first‑generation antihistamine that blocks peripheral H1 receptors to relieve allergic and related conditions.
  • Allergic skin reactions: reduces itching and inflammation associated with hives or dermatitis.
  • Pruritus: alleviates intense itching caused by dermatologic disorders.
  • Anxiety: provides short‑term relief of anxiety symptoms.
  • Sedation: induces calming effects useful before procedures.
  • Nausea: helps control nausea related to allergic responses.

How It Works

  • Hydroxyzine Hydrochloride acts as a selective antagonist at peripheral histamine H1 receptors, preventing histamine‑mediated vascular permeability, smooth‑muscle contraction and sensory nerve activation. Its anticholinergic activity contributes to sedation and reduced secretions, while central nervous system effects arise from modest antagonism of central H1 receptors, producing anxiolytic and antipruritic actions.

Side Effects

Common Side Effects

  • Drowsiness: feeling unusually sleepy or fatigued.
  • Dry mouth: reduced salivary flow causing thirst.
  • Dizziness: light‑headed sensation, especially when standing quickly.
  • Blurred vision: temporary focus changes.
  • Constipation: slowed intestinal motility.
  • Headache: mild to moderate pain.

Serious or Rare Side Effects

  • Cardiac arrhythmia: irregular heartbeat, potentially life‑threatening.
  • Severe allergic reaction (anaphylaxis): rapid onset of swelling, difficulty breathing, or rash.

Precautions & Warnings

Hydroxyzine Eg should be used with caution in certain populations and conditions.

  • Assess hepatic function: adjust use if severe liver impairment is present.
  • Monitor CNS depression: elderly patients may be more susceptible to sedation.
  • Avoid alcohol: may intensify drowsiness and impair coordination.
  • Use cautiously in glaucoma: anticholinergic effects can increase intra‑ocular pressure.
  • Pregnancy and lactation: safety not established; consult a healthcare professional.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Hydroxyzine Eg may interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • CNS depressants (e.g., opioids, benzodiazepines): increased sedation and respiratory depression.
  • QT‑prolonging agents (e.g., macrolide antibiotics, fluoroquinolones): heightened risk of cardiac arrhythmia.

Moderate Interactions (Monitor Closely)

  • Anticholinergic drugs (e.g., diphenhydramine): additive anticholinergic side effects.
  • Alcohol: may enhance drowsiness and impair alertness.
  • MAO inhibitors: potential for exaggerated hypotensive response.

Frequently Asked Questions

Hydroxyzine Eg contains hydroxyzine hydrochloride, a first‑generation antihistamine prescribed to relieve allergic skin reactions such as hives, to reduce intense itching (pruritus), to provide short‑term anxiety relief, to induce sedation before medical procedures, and to help control nausea associated with allergic responses.

Hydroxyzine hydrochloride blocks peripheral histamine H1 receptors, preventing histamine‑driven inflammation, itching, and vascular changes. Its anticholinergic activity also contributes to sedation and reduced secretions, while modest central H1 antagonism produces anxiolytic and antipruritic effects.

The appropriate dose of Hydroxyzine Eg is determined by the prescribing healthcare professional based on the individual’s condition, age, weight, and response to therapy. Dosage may vary widely, and patients should follow the exact instructions provided by their prescriber.

Safety data for hydroxyzine hydrochloride in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Hydroxyzine Eg.

To request Hydroxyzine Eg, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Hydroxyzine Eg is a first‑generation antihistamine, offering strong sedative and anticholinergic effects that many newer, second‑generation antihistamines lack. While it provides effective relief for itching and anxiety, its higher sedation profile may limit use when daytime alertness is required, unlike non‑sedating alternatives.

Store Hydroxyzine Eg at ambient temperature, preferably below 25 °C, in its original packaging to protect from moisture and light. Keep the product out of reach of children and avoid exposing it to extreme heat or humidity.

Hydroxyzine Eg is taken orally as directed by a healthcare professional. The tablet should be swallowed whole with a full glass of water, and dosing times (e.g., with or without food) should follow the prescriber’s instructions.

Serious adverse reactions to Hydroxyzine Eg can include cardiac arrhythmias such as QT prolongation, severe allergic responses (anaphylaxis), and rare neurological events like seizures. Patients should seek immediate medical attention if they experience rapid heartbeat, difficulty breathing, or severe skin reactions.

Hydroxyzine Eg should be avoided in individuals with known hypersensitivity to hydroxyzine or other first‑generation antihistamines, in patients with severe liver disease, and in those with a history of prolonged QT interval or significant cardiac conduction disorders unless closely monitored.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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