Product image of Hydroxyzine Eql Pharma (Hydroxyzine Hydrochloride) supplied by GNH India

Hydroxyzine Eql Pharma

Active Ingredient:
Hydroxyzine Hydrochloride
Origin:
EU

Hydroxyzine Eql Pharma (Hydroxyzine Hydrochloride)

Hydroxyzine Hydrochloride, the active ingredient in Hydroxyzine Eql Pharma, is a first‑generation antihistamine presented as an oral formulation for oral use. It is employed to relieve symptoms of allergic conditions, manage anxiety, provide sedation, and control nausea and vomiting in adult patients.
GNH India supplies Hydroxyzine Eql Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Eql Pharma Ab

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Indications & Clinical Uses

Hydroxyzine Hydrochloride is a first‑generation antihistamine that acts on histamine‑mediated conditions.

  • Allergic rhinitis: reduces nasal itching, sneezing, and congestion.
  • Urticaria: alleviates hives and itching.
  • Anxiety: provides short‑term relief of tension and nervousness.
  • Sedation: induces calmness before procedures or for sleep support.
  • Nausea and vomiting: helps control symptoms associated with motion or medication‑induced emesis.

How It Works

  • Hydroxyzine Hydrochloride selectively antagonizes peripheral histamine H1 receptors, preventing histamine‑induced vasodilation, increased vascular permeability, and sensory nerve stimulation. By blocking these receptors, it diminishes allergic inflammation and exerts central nervous system depressant effects that contribute to its anxiolytic and sedative properties.

Side Effects

Hydroxyzine may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Drowsiness: feeling unusually sleepy or fatigued.
  • Dry mouth: reduced salivation leading to thirst.
  • Blurred vision: temporary difficulty focusing.
  • Constipation: slowed gastrointestinal motility.
  • Headache: mild to moderate cranial pain.

Serious or Rare Side Effects

  • Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Cardiac arrhythmias: irregular heart rhythms.
  • Seizures: convulsive episodes in susceptible individuals.
  • Anaphylaxis: life‑threatening allergic response.
  • Blood dyscrasias: abnormal blood cell counts, including agranulocytosis.

Precautions & Warnings

Before using Hydroxyzine, consider the following safety measures.

  • Pregnancy: consult a healthcare professional before use.
  • Elderly patients: monitor for enhanced sedation and falls.
  • Driving or operating machinery: avoid until the effect on alertness is known.
  • Concomitant CNS depressants: assess risk of additive drowsiness.
  • Renal or hepatic impairment: dose adjustment may be required.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, and protect from moisture.

Avoid Interactions

Hydroxyzine can interact with several medicines, altering its safety or effectiveness.

Major Interactions (Avoid)

  • CNS depressants (e.g., benzodiazepines, barbiturates): may cause profound sedation.
  • Anticholinergic agents (e.g., atropine, tricyclic antidepressants): increase dry‑mouth and constipation.
  • MAO inhibitors: risk of hypertensive reactions when combined with certain sympathomimetics.

Moderate Interactions (Monitor Closely):\n- Alcohol: enhances drowsiness and impairment.

  • Opioid analgesics: additive central nervous system depression.
  • Other antihistamines: may intensify sedation and anticholinergic effects.

Frequently Asked Questions

Hydroxyzine Eql Pharma is prescribed to manage allergic rhinitis, urticaria (hives), short‑term anxiety, procedural sedation, and to control nausea or vomiting associated with motion or certain medications.

Hydroxyzine hydrochloride blocks peripheral H1 histamine receptors, reducing the effects of histamine release such as itching, swelling, and vasodilation. Its central action also depresses the nervous system, providing anxiolytic and sedative effects.

The specific dose of Hydroxyzine Eql Pharma is determined by the prescribing clinician based on the patient’s age, condition being treated, and overall health status. Dosage instructions should always follow the prescriber’s guidance.

Safety of hydroxyzine during pregnancy or while breastfeeding has not been definitively established. Women who are pregnant, planning to become pregnant, or nursing should discuss potential risks and benefits with their healthcare provider before using this medication.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Hydroxyzine is a first‑generation antihistamine, which tends to cause more sedation and anticholinergic effects than second‑generation agents such as cetirizine or loratadine. It is often chosen when a sedative effect is desired, whereas newer antihistamines are preferred for daytime allergy control with minimal drowsiness.

Hydroxyzine Eql Pharma should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use.

Hydroxyzine Eql Pharma is taken orally, usually as a tablet or liquid formulation, as directed by a healthcare professional. It should be swallowed with water and can be taken with or without food, unless otherwise instructed by the prescriber.

Serious risks include severe skin reactions such as Stevens‑Johnson syndrome, cardiac arrhythmias, seizures, anaphylactic reactions, and blood dyscrasias like agranulocytosis. Patients should seek immediate medical attention if they experience rash, difficulty breathing, irregular heartbeat, or unexplained fever.

Hydroxyzine should be avoided in individuals with known hypersensitivity to hydroxyzine or other first‑generation antihistamines, patients with severe hepatic impairment, and those taking certain contraindicated medications. It is also not recommended for patients who require full mental alertness, such as pilots or heavy machinery operators, unless cleared by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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