Product image of Hydroxyzine Medical Valley (Hydroxyzine Hydrochloride) supplied by GNH India

Hydroxyzine Medical Valley

Active Ingredient:
Hydroxyzine Hydrochloride
Origin:
EU

Hydroxyzine Medical Valley (Hydroxyzine Hydrochloride)

Hydroxyzine, the active ingredient in Hydroxyzine Medical Valley, is a first‑generation antihistamine presented as an oral dosage form for oral use. It treats allergic conditions such as rhinitis and urticaria, helps relieve anxiety and tension, and provides sedation before or after surgical procedures.

GNH India supplies Hydroxyzine Medical Valley as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Medical Valley Invest Ab

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Indications & Clinical Uses

  • Hydroxyzine acts on histamine H1 receptors to alleviate symptoms of allergic and anxiety‑related conditions.
  • Allergic rhinitis: reduces nasal itching, sneezing and congestion.
  • Urticaria (hives): diminishes wheal formation and itching.
  • Anxiety and tension: provides calming effect and reduces nervousness.
  • Sedation before/after surgery: induces pre‑operative calm and postoperative sleep.
  • Nausea and vomiting: helps control postoperative and motion‑related nausea.

How It Works

  • Hydroxyzine selectively antagonizes peripheral histamine H1 receptors, preventing histamine‑mediated allergic responses. It also penetrates the central nervous system, producing sedative and anticholinergic effects that contribute to its anxiolytic and anti‑emetic properties.

Side Effects

Hydroxyzine may cause a range of adverse reactions.

Common Side Effects

  • Drowsiness or sedation
  • Dry mouth
  • Blurred vision
  • Constipation
  • Headache
  • Dizziness

Serious or Rare Side Effects

  • Severe allergic reactions (anaphylaxis)
  • Cardiac arrhythmias or QT prolongation
  • Seizures
  • Hepatic dysfunction
  • Blood dyscrasias (e.g., agranulocytosis)
  • Extrapyramidal symptoms

Precautions & Warnings

  • Hydroxyzine should be used with caution in specific situations.
  • Pregnancy: Category B – use only if potential benefit justifies the risk.
  • Elderly: increased sensitivity to sedation and anticholinergic effects.
  • Driving: avoid operating machinery until individual response is known.
  • Alcohol: avoid concurrent consumption due to enhanced CNS depression.
  • Drug interactions: review all concomitant medications for potential additive effects.
  • Store at ambient temperature below 25°C: keep in original packaging, protect from moisture and light.

Avoid Interactions

Hydroxyzine can interact with several drug classes.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): risk of severe hypotension.
  • Central nervous system depressants (benzodiazepines, opioids): additive sedation.
  • Anticholinergic agents: heightened anticholinergic burden.
  • QT‑prolonging drugs: increased risk of cardiac arrhythmias.
  • Alcohol: potentiates sedative effects.

Moderate Interactions (Monitor Closely):\n- Antihypertensives: may enhance hypotensive response.

  • Other antihistamines: additive drowsiness.
  • CYP450 inhibitors or inducers: may alter hydroxyzine plasma levels.
  • Anticholinergic medications: monitor for excessive dry mouth and constipation.

Frequently Asked Questions

Hydroxyzine Medical Valley is prescribed to relieve symptoms of allergic rhinitis and urticaria, to reduce anxiety and tension, to provide sedation before or after surgical procedures, and to control nausea and vomiting associated with various triggers.

Hydroxyzine works by selectively blocking peripheral histamine H1 receptors, which reduces allergic reactions, and by crossing the blood‑brain barrier to exert central sedative and anticholinergic effects that help calm anxiety and prevent nausea.

The appropriate dose of Hydroxyzine Medical Valley is determined by the prescribing healthcare professional based on the patient’s condition, age, weight, and response to therapy. Patients should follow the prescriber’s instructions exactly.

Hydroxyzine is classified as Pregnancy Category B, indicating that animal studies have not shown risk to the fetus, but there are limited human data. It should be used only if the potential benefit outweighs any possible risk, and breastfeeding mothers should consult their physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and import documentation.

Hydroxyzine is a first‑generation antihistamine, which provides both peripheral H1 blockade and central sedation. Unlike newer second‑generation antihistamines that cause less drowsiness, hydroxyzine’s sedative properties make it useful for anxiety and pre‑operative sedation, but also increase the likelihood of CNS side effects.

Hydroxyzine Medical Valley should be stored at ambient temperature below 25 °C, in its original packaging, protected from moisture and direct light to maintain stability and potency.

Hydroxyzine Medical Valley is taken orally, usually as a tablet or liquid preparation, as directed by a healthcare professional. It should be swallowed with water and taken with or without food according to the prescriber’s guidance.

Serious risks include severe allergic reactions such as anaphylaxis, cardiac arrhythmias or QT prolongation, seizures, and rare blood disorders. Patients should seek immediate medical attention if they experience symptoms like rash, difficulty breathing, palpitations, or unexplained bruising.

Hydroxyzine should be avoided in individuals with known hypersensitivity to hydroxyzine or other first‑generation antihistamines, in patients taking monoamine oxidase inhibitors, and in those with severe liver impairment or prolonged QT interval unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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