Hydroxyzine Orifarm (Hydroxyzine Hydrochloride)

Hydroxyzine hydrochloride works by selectively blocking peripheral H1 histamine receptors, which reduces the effects of histamine on blood vessels and nerves. It also has anticholinergic activity and central H1 antagonism, producing sedative and anxiolytic effects that contribute to its therapeutic benefits.

The appropriate dose of Hydroxyzine Orifarm is determined by the prescribing healthcare professional based on the patient’s condition, age, weight, and response to therapy. Dosage regimens are individualized and should follow the prescriber’s instructions and local regulatory guidelines.

Safety data for hydroxyzine hydrochloride in pregnancy and lactation are limited, and the product is classified as pregnancy category unknown. It should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by a qualified healthcare provider.

To order Hydroxyzine Orifarm, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Hydroxyzine is a first‑generation antihistamine, which means it readily crosses the blood‑brain barrier and can cause sedation and anticholinergic effects. Second‑generation antihistamines, such as cetirizine or loratadine, are less sedating but may be less effective for anxiety or procedural sedation. Choice depends on the clinical need and patient tolerance.

Hydroxyzine Orifarm should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight and heat sources. Ensure the container is tightly closed to maintain product stability throughout its shelf life.

Hydroxyzine Orifarm is administered orally. The tablet or capsule should be swallowed whole with a glass of water. It may be taken with or without food, according to the prescriber’s guidance, and the patient should follow the dosing schedule provided by the healthcare professional.

Serious risks include cardiac arrhythmias, severe hypotension, and rare anaphylactic reactions. Patients with known heart conduction disorders, uncontrolled hypertension, or a history of severe allergic responses should be monitored closely, and any signs of these serious events require immediate medical attention.

Hydroxyzine Orifarm should be avoided in individuals with known hypersensitivity to hydroxyzine or any component of the formulation, in patients with prolonged QT interval or other significant cardiac conduction abnormalities, and in those taking contraindicated medications such as MAO inhibitors. Caution is also advised for the elderly and patients with hepatic impairment.