Product image of Hydroxyzinum Amara (Hydroxyzine Hydrochloride) supplied by GNH India

Hydroxyzinum Amara

Active Ingredient:
Hydroxyzine Hydrochloride
Origin:
EU

Hydroxyzinum Amara (Hydroxyzine Hydrochloride)

Hydroxyzine hydrochloride, the active ingredient in Hydroxyzinum Amara, is a first‑generation H1‑receptor antagonist presented as an oral tablet for oral use. It is employed to relieve allergic skin reactions, reduce anxiety, provide sedation before procedures, and control nausea and vomiting.

GNH India supplies Hydroxyzinum Amara as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across markets.

Manufacturer / TM Owner

Zaklad Farmaceutyczny Amara Sp Zoo

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Hydroxyzine hydrochloride is used for several conditions that involve histamine‑mediated responses and central nervous system effects.

  • Allergic dermatoses and pruritus: reduces itching and skin inflammation associated with allergic reactions.
  • Anxiety and tension relief: provides calming effects to alleviate mild to moderate anxiety.
  • Sedation before/after surgery: induces sedation and anxiolysis for pre‑operative and post‑operative comfort.
  • Nausea and vomiting: helps control nausea and vomiting related to various causes.

How It Works

  • Hydroxyzine hydrochloride acts as a selective antagonist of peripheral histamine H1 receptors, preventing histamine‑induced vasodilation, increased vascular permeability, and sensory nerve stimulation. Its anticholinergic activity contributes to sedation, while central H1 blockade produces anxiolytic and antiemetic effects. The combined actions reduce allergic symptoms, induce calmness, and diminish nausea.

Side Effects

Hydroxyzine may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Drowsiness: feeling of sleepiness or reduced alertness.
  • Dry mouth: decreased salivation leading to a dry sensation.
  • Blurred vision: temporary visual disturbances.
  • Constipation: slowed gastrointestinal motility.

Serious or Rare Side Effects

  • Cardiac arrhythmia: irregular heart rhythm requiring medical attention.
  • Severe allergic reaction: rash, swelling, or difficulty breathing.
  • Hepatotoxicity: signs of liver injury such as jaundice.
  • Seizures: rare occurrence of convulsive episodes.

Precautions & Warnings

Hydroxyzine should be used with caution in specific populations and situations.

  • Pregnancy: use only if potential benefit justifies risk, as safety data are limited.
  • Elderly: monitor for enhanced sedation and anticholinergic effects.
  • Driving: avoid operating machinery until individual response is known.
  • Drug interactions: review concomitant medications for additive CNS depression.
  • Renal or hepatic impairment: dose may require adjustment under medical supervision.
  • Store at ambient temperature below 25°C: keep in original packaging, protect from moisture and light.

Avoid Interactions

Hydroxyzine can interact with several medicines, altering its effects or increasing adverse reactions.

Major Interactions (Avoid)

  • CNS depressants: combined use may cause profound sedation or respiratory depression.
  • MAO inhibitors: may increase risk of hypertensive crisis or severe hypotension.
  • Anticholinergic drugs: additive anticholinergic burden leading to confusion or urinary retention.

Moderate Interactions (Monitor Closely)

  • Alcohol: enhances drowsiness and impairments.
  • Other antihistamines: may increase sedation and anticholinergic side effects.
  • QT‑prolonging agents: potential additive effect on cardiac repolarization.

Frequently Asked Questions

Hydroxyzinum Amara contains hydroxyzine hydrochloride and is prescribed to treat allergic skin conditions with itching, to relieve mild to moderate anxiety, to provide sedation before or after surgical procedures, and to control nausea and vomiting associated with various causes.

Hydroxyzine blocks peripheral H1 histamine receptors, preventing the actions of histamine that cause itching, swelling, and vasodilation. It also has anticholinergic properties that contribute to sedation, and central H1 blockade that produces anxiolytic and anti‑emetic effects.

The appropriate dose is determined by the prescribing clinician based on the patient’s condition, age, weight, and response. Hydroxyzinum Amara is a prescription‑only product, and dosing instructions should be obtained from a qualified health‑care professional.

Safety data for hydroxyzine in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any possible risk to the fetus or infant, and the decision should be made in consultation with a health‑care provider.

Enquiries can be submitted on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Hydroxyzinum Amara is a first‑generation H1 antagonist, which provides both antihistaminic and sedative effects. Compared with second‑generation agents such as cetirizine, it is more likely to cause drowsiness but may be preferred when sedation or anxiolysis is also desired.

Store the oral tablets at ambient temperature below 25 °C, in the original container, protected from moisture and direct light. Do not expose the product to excessive heat or humidity, and keep it out of reach of children.

Hydroxyzinum Amara is taken orally as a tablet. The tablet should be swallowed whole with a glass of water, unless otherwise directed by a health‑care professional. It is usually taken with or without food as prescribed.

Serious adverse reactions, although rare, include cardiac arrhythmias, severe allergic responses such as rash or difficulty breathing, liver injury indicated by jaundice, and seizures. Any of these symptoms require immediate medical attention.

Hydroxyzinum Amara should be avoided in individuals with known hypersensitivity to hydroxyzine or other first‑generation antihistamines, in patients with severe hepatic impairment, and in those taking monoamine oxidase inhibitors within 14 days. Caution is also advised for the elderly and for patients with glaucoma or urinary retention.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Hydroxyzine Hydrochloride

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT