Product image of Hyoscine Butylbromide Crescent Pharma (Hyoscine Butylbromide) supplied by GNH India

Hyoscine Butylbromide Crescent Pharma

Active Ingredient:
Hyoscine Butylbromide
Origin:
EU

Hyoscine Butylbromide Crescent Pharma (Hyoscine Butylbromide)

Hyoscine Butylbromide, the active ingredient in Hyoscine Butylbromide Crescent Pharma, is an anticholinergic antispasmodic presented as an oral formulation for oral use. It relieves smooth‑muscle spasm in the gastrointestinal tract and is used to treat abdominal cramps, colic and related pain.

GNH India supplies Hyoscine Butylbromide Crescent Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Crescent Pharma Limited

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Indications & Clinical Uses

Hyoscine Butylbromide acts on smooth‑muscle spasm in the gastrointestinal and biliary systems, providing relief in several conditions.

  • Abdominal cramps: reduces intensity and frequency of painful contractions.
  • Irritable bowel syndrome: alleviates cramping and abdominal discomfort.
  • Renal colic: eases spasm of the ureteral smooth muscle.
  • Biliary colic: relaxes biliary tract smooth muscle to lessen pain.
  • Menstrual pain: diminishes uterine smooth‑muscle cramps.

How It Works

  • Hyoscine Butylbromide is a peripheral muscarinic receptor antagonist. By blocking M3 receptors on smooth‑muscle cells in the gastrointestinal, urinary and biliary tracts, it prevents acetylcholine‑mediated contraction, leading to muscle relaxation and relief of spasm without crossing the blood‑brain barrier.

Side Effects

Hyoscine Butylbromide may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Dry mouth
  • Blurred vision
  • Constipation
  • Urinary retention
  • Tachycardia
  • Dizziness

Serious or Rare Side Effects

  • Allergic reactions (rash, itching, swelling)
  • Severe skin rash or Stevens‑Johnson syndrome
  • Difficulty swallowing (dysphagia)
  • Severe constipation or paralytic ileus
  • Cardiac arrhythmia
  • Acute glaucoma exacerbation

Precautions & Warnings

Before prescribing Hyoscine Butylbromide, consider the following safety measures.

  • Assess renal function: adjust use in severe renal impairment.
  • Avoid in known hypersensitivity: discontinue if allergic reaction occurs.
  • Caution in glaucoma patients: anticholinergic effect may raise intra‑ocular pressure.
  • Use carefully in elderly: higher risk of anticholinergic side effects.
  • Pregnancy and lactation: safety not established; consult physician.
  • Store at ambient temperature: keep in original container, protect from moisture.

Avoid Interactions

Hyoscine Butylbromide can interact with several drug classes, requiring attention to avoid additive effects.

Major Interactions (Avoid)

  • Anticholinergic agents: additive anticholinergic burden.
  • Tricyclic antidepressants: increased anticholinergic side effects.
  • Antihistamines: enhanced dry mouth and constipation.
  • Opioids: may potentiate constipation.
  • Antipsychotics with anticholinergic properties: increased risk of side effects.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may mask tachycardia.
  • CYP3A4 inhibitors: possible increase in plasma levels.
  • Alcohol: may intensify dizziness.
  • Diuretics: risk of urinary retention.
  • Anticholinesterase drugs: reduced efficacy of Hyoscine Butylbromide.

Frequently Asked Questions

Hyoscine Butylbromide Crescent Pharma is used to relieve smooth‑muscle spasm in the gastrointestinal, biliary and urinary tracts. It is indicated for abdominal cramps, irritable bowel syndrome, renal and biliary colic, and menstrual pain, providing symptomatic relief from painful contractions.

The drug acts as a peripheral muscarinic receptor antagonist, blocking M3 receptors on smooth‑muscle cells. This inhibition prevents acetylcholine‑induced contraction, leading to relaxation of the gastrointestinal, biliary and urinary smooth muscle, thereby reducing spasm and associated pain.

The appropriate dose of Hyoscine Butylbromide is determined by the prescribing healthcare professional based on the patient’s condition, age, and response. Dosage may vary between adults and children and should follow the prescriber’s instructions on the product label.

Safety of Hyoscine Butylbromide during pregnancy and lactation has not been fully established. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made in consultation with a qualified healthcare provider.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Hyoscine Butylbromide is a peripheral anticholinergic that does not cross the blood‑brain barrier, offering targeted smooth‑muscle relaxation with fewer central side effects compared with agents like dicyclomine. It is often preferred for acute colic and cramp relief where rapid onset is desired.

Store the product at ambient temperature, ideally below 25 °C. Keep it in the original packaging to protect from moisture and light. Do not store in a refrigerator or freezer unless otherwise indicated on the label.

Hyoscine Butylbromide is administered orally, typically as a tablet or capsule, and should be taken with water as directed by the prescriber. The dosage form is designed for systemic absorption to act on peripheral muscarinic receptors.

Serious risks include severe allergic reactions, acute glaucoma exacerbation, paralytic ileus, and cardiac arrhythmias. Patients should seek immediate medical attention if they experience symptoms such as rash, difficulty breathing, visual disturbances, severe abdominal pain, or irregular heartbeats.

Hyoscine Butylbromide should be avoided in individuals with known hypersensitivity to the drug, severe glaucoma, myasthenia gravis, or significant urinary retention. Caution is also advised for patients with severe renal impairment, and it should be used only under medical supervision in pregnant or breastfeeding women.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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