Product image of Hyoscine Butylbromide Milpharm Limited (Hyoscine Butylbromide) supplied by GNH India

Hyoscine Butylbromide Milpharm Limited

Active Ingredient:
Hyoscine Butylbromide
Origin:
EU

Hyoscine Butylbromide Milpharm Limited (Hyoscine Butylbromide)

Hyoscine Butylbromide, the active ingredient in Hyoscine Butylbromide Milpharm Limited, is an anticholinergic (antispasmodic) presented as an oral dosage form for oral use. It relieves smooth‑muscle spasm in the gastrointestinal and urinary tracts, helping to reduce abdominal pain and related symptoms.

GNH India supplies Hyoscine Butylbromide Milpharm Limited as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Milpharm Limited

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Indications & Clinical Uses

Hyoscine Butylbromide is an anticholinergic antispasmodic that acts on smooth‑muscle disorders of the gastrointestinal and urinary systems.

  • Abdominal cramps: reduces painful cramping by relaxing intestinal smooth muscle.
  • Irritable bowel syndrome: alleviates bowel spasm and associated discomfort.
  • Gastrointestinal spasm: eases spasmodic episodes throughout the GI tract.
  • Renal colic: diminishes ureteral spasm to facilitate stone passage.

How It Works

  • Hyoscine Butylbromide competitively blocks muscarinic acetylcholine receptors, particularly the M3 subtype, on gastrointestinal smooth‑muscle cells. This antagonism lowers intracellular calcium release, leading to relaxation of smooth muscle and decreased spasm, while also reducing glandular secretions.

Side Effects

Common Side Effects

  • Dry mouth
  • Blurred vision
  • Constipation
  • Dizziness
  • Tachycardia
  • Urinary retention

Serious or Rare Side Effects

  • Allergic reactions (rash, itching, swelling)
  • Anaphylaxis
  • Severe hypotension
  • Paralytic ileus
  • Acute angle‑closure glaucoma

Precautions & Warnings

Hyoscine Butylbromide should be used with caution in certain patient groups and clinical situations.

  • Assess renal function: adjust use in severe renal impairment.
  • Avoid in known hypersensitivity to hyoscine butylbromide.
  • Use caution in glaucoma patients: may increase intra‑ocular pressure.
  • Monitor anticholinergic burden in the elderly: risk of confusion and falls.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Hyoscine Butylbromide may interact with other medications that possess anticholinergic or related pharmacologic properties.

Major Interactions (Avoid)

  • Other anticholinergics (e.g., atropine, scopolamine): additive anticholinergic effects.
  • Tricyclic antidepressants: increased risk of anticholinergic toxicity.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may mask tachycardia caused by anticholinergic action.
  • Opioids: may enhance constipation.
  • Diuretics: may increase risk of urinary retention.

Frequently Asked Questions

Hyoscine Butylbromide is employed to relieve smooth‑muscle spasm in the gastrointestinal and urinary tracts. It is indicated for conditions such as abdominal cramps, irritable bowel syndrome, gastrointestinal spasm, and renal colic, helping to reduce pain and improve comfort.

The drug acts as a competitive antagonist at muscarinic acetylcholine receptors, especially the M3 subtype. By blocking these receptors, it reduces calcium‑mediated contraction of smooth muscle, leading to relaxation of the gastrointestinal tract and decreased spasm.

Dosage is individualized and should be determined by a qualified prescriber based on the patient’s condition, age, and response. Healthcare professionals consider clinical guidelines and patient factors when selecting the appropriate strength and frequency.

The pregnancy safety category for Hyoscine Butylbromide is not clearly defined. It should only be used during pregnancy or lactation if the potential benefit justifies any potential risk, and under the guidance of a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Hyoscine Butylbromide is an anticholinergic agent, similar to drugs like dicyclomine or mebeverine. Compared with other classes, it provides rapid relief of smooth‑muscle spasm but may have a higher incidence of anticholinergic side effects such as dry mouth and blurred vision.

Store the product at temperatures below 25 °C, keeping it in the original packaging to protect from moisture. Avoid exposure to excessive heat or humidity, and keep the container tightly closed when not in use.

Hyoscine Butylbromide is administered orally. The tablet (or other oral dosage form) should be swallowed whole with a glass of water, unless otherwise directed by a healthcare professional.

Serious adverse reactions can include severe allergic responses such as anaphylaxis, acute angle‑closure glaucoma, paralytic ileus, and marked hypotension. Patients should seek immediate medical attention if they experience symptoms like swelling, difficulty breathing, or sudden vision changes.

Hyoscine Butylbromide is contraindicated in individuals with known hypersensitivity to the drug, those with narrow‑angle glaucoma, severe urinary retention, myasthenia gravis, or significant gastrointestinal obstruction. Consultation with a healthcare provider is essential before starting therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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