Product image of Hyoscine Butylbromide Morningside Healthcare (Hyoscine Butylbromide) supplied by GNH India

Hyoscine Butylbromide Morningside Healthcare

Active Ingredient:
Hyoscine Butylbromide
Origin:
EU

Hyoscine Butylbromide Morningside Healthcare (Hyoscine Butylbromide)

Hyoscine Butylbromide, the active ingredient in Hyoscine Butylbromide Morningside Healthcare, is an anticholinergic (antispasmodic) presented as an oral dosage form for oral use. It treats abdominal cramps, irritable bowel syndrome and biliary colic in adults.

GNH India supplies Hyoscine Butylbromide Morningside Healthcare as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Morningside Healthcare Ltd

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Indications & Clinical Uses

Hyoscine Butylbromide is used to relieve smooth‑muscle spasm in the gastrointestinal and biliary tracts.

  • Abdominal cramps: reduces pain by relaxing intestinal smooth muscle.
  • Irritable bowel syndrome: alleviates spasm‑related discomfort and cramping.
  • Biliary colic: eases biliary tract spasm and associated pain.

How It Works

  • Hyoscine Butylbromide acts as a competitive antagonist at muscarinic (M1‑M3) receptors in the gastrointestinal and biliary smooth muscle. By blocking acetylcholine binding, it prevents calcium influx and reduces muscle contractility, leading to relaxation of the affected smooth‑muscle segments and relief of spasm.

Side Effects

Common Side Effects

  • Dry mouth
  • Blurred vision
  • Constipation
  • Urinary retention
  • Tachycardia
  • Dizziness

Serious or Rare Side Effects

  • Allergic reactions (rash, pruritus, angioedema)
  • Severe hypotension
  • Paralytic ileus
  • Anaphylaxis
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Cardiac arrhythmias

Precautions & Warnings

Hyoscine Butylbromide should be used with caution in certain patient groups and situations.

  • Assess renal or hepatic impairment: consider dose adjustment or monitoring.
  • Avoid in patients with known hypersensitivity to hyoscine butylbromide.
  • Use caution in glaucoma patients: anticholinergic activity may increase intra‑ocular pressure.
  • Monitor for urinary retention in patients with prostate enlargement.
  • Avoid concomitant use with other anticholinergics unless medically indicated.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Hyoscine Butylbromide may interact with several other medicines.

Major Interactions (Avoid)

  • Other anticholinergics: additive anticholinergic effects may increase risk of dry mouth, constipation, and tachycardia.
  • Antihistamines with anticholinergic properties: heightened anticholinergic burden.
  • Tricyclic antidepressants: enhanced anticholinergic side‑effects.

Moderate Interactions (Monitor Closely)

  • Metoclopramide: may reduce the antispasmodic efficacy of hyoscine.
  • Opioid analgesics: additive risk of constipation.
  • Beta‑blockers: may mask tachycardia caused by anticholinergic activity.

Frequently Asked Questions

Hyoscine Butylbromide is prescribed to relieve smooth‑muscle spasm associated with abdominal cramps, irritable bowel syndrome and biliary colic. By relaxing the gastrointestinal and biliary tract muscles, it helps reduce pain and discomfort in these conditions.

The drug blocks muscarinic (M1‑M3) receptors on smooth‑muscle cells, preventing acetylcholine from triggering contraction. This antagonism reduces calcium influx, leading to muscle relaxation and alleviation of spasm in the gut and biliary system.

The appropriate dose of Hyoscine Butylbromide is determined by the prescribing clinician based on the patient’s condition, age, weight and overall health. Dosage instructions are provided on the prescription label and should be followed exactly.

Safety data for Hyoscine Butylbromide in pregnancy or lactation are limited. Healthcare providers should evaluate the risk‑benefit profile before prescribing to pregnant or nursing women, and use only if clearly needed.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Hyoscine Butylbromide is a peripheral anticholinergic that does not cross the blood‑brain barrier, offering targeted smooth‑muscle relaxation with fewer central nervous system effects compared with some other antispasmodics like dicyclomine. Its rapid onset makes it useful for acute spasm relief.

Store the product at ambient temperature below 25 °C. Keep it in the original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Hyoscine Butylbromide is taken orally, typically as a tablet or capsule, with or without food as directed by the prescriber. Swallow the dosage form whole with a glass of water; do not crush or chew unless specifically instructed.

Serious risks include severe allergic reactions (e.g., anaphylaxis), paralytic ileus, marked hypotension, and rare skin disorders such as Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience symptoms like swelling, difficulty breathing, severe abdominal pain or rash.

Hyoscine Butylbromide should be avoided in individuals with known hypersensitivity to the drug, in patients with narrow‑angle glaucoma, severe urinary retention, or myasthenia gravis, and in anyone for whom anticholinergic therapy is contraindicated.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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