Product image of Hyoscine Butylbromide Ria Generics (Hyoscine Butylbromide) supplied by GNH India

Hyoscine Butylbromide Ria Generics

Active Ingredient:
Hyoscine Butylbromide
Origin:
EU

Hyoscine Butylbromide Ria Generics (Hyoscine Butylbromide)

Hyoscine Butylbromide, the active ingredient in Hyoscine Butylbromide Ria Generics, is an anticholinergic (muscarinic antagonist) presented as an oral formulation for oral use. It relieves abdominal cramp, biliary colic, renal colic and other gastrointestinal smooth‑muscle spasm in adults.

GNH India supplies Hyoscine Butylbromide Ria Generics as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ria Generics Ltd.

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Indications & Clinical Uses

Hyoscine Butylbromide acts on smooth‑muscle receptors to reduce spasm in several abdominal conditions.

  • Abdominal cramp and pain: reduces spasm and associated discomfort.
  • Biliary colic: eases biliary tract smooth‑muscle contraction.
  • Renal colic: diminishes renal‑tract spasm and pain.
  • Gastrointestinal smooth‑muscle spasm: lessens spasms and related symptoms.

How It Works

  • Hyoscine Butylbromide competitively blocks muscarinic acetylcholine receptors on smooth‑muscle cells, preventing acetylcholine‑mediated contraction. This antagonism leads to relaxation of gastrointestinal, biliary and urinary tract smooth muscle, thereby reducing spasm and the pain that accompanies it.

Side Effects

Hyoscine Butylbromide may cause a range of adverse reactions, most of which are related to its anticholinergic activity.

Common Side Effects

  • Dry mouth: reduced salivary secretion.
  • Blurred vision: accommodation difficulty.
  • Constipation: decreased gastrointestinal motility.
  • Urinary retention: difficulty emptying the bladder.
  • Tachycardia: increased heart rate.
  • Dizziness: light‑headed sensation.

Serious or Rare Side Effects

  • Allergic reactions: rash, pruritus, or angioedema.
  • Severe tachycardia: markedly elevated heart rate.
  • Confusion or hallucinations: central anticholinergic effects.
  • Severe hypotension: sudden drop in blood pressure.
  • Anaphylaxis: life‑threatening systemic reaction.
  • Persistent urinary retention requiring catheterisation.

Precautions & Warnings

When prescribing Hyoscine Butylbromide, consider the following safety measures.

  • Glaucoma: avoid or use with caution due to increased intra‑ocular pressure.
  • Urinary retention: monitor for worsening symptoms.
  • Elderly patients: increased sensitivity to anticholinergic effects.
  • Cardiac disease: observe for tachycardia or arrhythmias.
  • Hepatic impairment: dose adjustment may be required.
  • Store at ambient temperature: keep in original packaging, protect from moisture and excessive heat.

Avoid Interactions

Hyoscine Butylbromide can interact with other medications that share anticholinergic properties or affect its metabolism.

Major Interactions (Avoid)

  • Other anticholinergics (e.g., antihistamines, tricyclic antidepressants): additive anticholinergic burden.
  • Quinidine: may increase plasma concentrations of hyoscine.
  • Potent CYP3A4 inhibitors: potential increase in exposure if metabolised via this pathway.

Moderate Interactions (Monitor Closely)

  • Other antispasmodics: risk of excessive smooth‑muscle relaxation.
  • MAO inhibitors: possible enhancement of anticholinergic effects.
  • Beta‑blockers: may mask tachycardia caused by hyoscine.

Frequently Asked Questions

Hyoscine Butylbromide is used to relieve abdominal cramp and pain, biliary colic, renal colic and other gastrointestinal smooth‑muscle spasms. It works by relaxing the smooth muscle in the digestive, biliary and urinary tracts, reducing spasm‑related discomfort.

The drug competitively blocks muscarinic acetylcholine receptors on smooth‑muscle cells. By preventing acetylcholine from binding, it stops the muscle contraction cascade, leading to relaxation of the gastrointestinal, biliary and urinary tract smooth muscle and alleviating spasm.

The appropriate dose of Hyoscine Butylbromide is determined by the prescribing healthcare professional based on the patient’s condition, age, weight and response to therapy. Dosage regimens may vary, and the prescriber will provide specific instructions.

Safety data for Hyoscine Butylbromide in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Hyoscine Butylbromide is a peripheral anticholinergic agent that primarily acts on muscarinic receptors, offering rapid relief of smooth‑muscle spasm with limited central nervous system penetration. Compared with agents such as dicyclomine, it has a shorter duration of action and a lower risk of central side effects.

Store the product at ambient temperature, preferably below 25 °C. Keep it in the original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

Hyoscine Butylbromide is administered orally. The tablet or capsule is swallowed with water, usually on an empty stomach or as directed by the prescriber. Do not crush or chew the dosage form unless specifically instructed.

Serious risks include severe allergic reactions (rash, angioedema, anaphylaxis), marked tachycardia, significant hypotension, and central anticholinergic effects such as confusion or hallucinations. Patients should seek immediate medical attention if any of these symptoms occur.

Hyoscine Butylbromide should be avoided in individuals with known hypersensitivity to the drug, uncontrolled glaucoma, severe urinary retention, or significant cardiac arrhythmias. It is also contraindicated in patients where anticholinergic effects could exacerbate existing conditions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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