Product image of Hypericum Nature's Bounty (Dry Extract Of St. John's Wort (5-7:1), Extraction Solvent: Ethanol 60% V/V) supplied by GNH India

Hypericum Nature's Bounty

Active Ingredient:
Dry Extract Of St. John's Wort (5-7:1), Extraction Solvent: Ethanol 60% V/V
Origin:
EU

Hypericum Nature's Bounty (Dry Extract Of St. John's Wort (5-7:1), Extraction Solvent: Ethanol 60% V/V)

Hypericum perforatum, the active ingredient in Hypericum Nature's Bounty, is a herbal antidepressant presented as a dry extract for oral use. It is employed to manage mild to moderate depression, seasonal affective disorder and anxiety in adult patients.

GNH India supplies Hypericum Nature's Bounty as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for global distribution. Products are manufactured under GMP conditions and are available for bulk and retail orders.

Manufacturer / TM Owner

Holland & Barrett Limited

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Indications & Clinical Uses

  • Hypericum perforatum acts as an herbal antidepressant influencing neurotransmitter pathways linked to mood regulation.
  • Mild to moderate depression: helps alleviate depressive symptoms in adults.
  • Seasonal affective disorder: reduces mood disturbances associated with seasonal changes.
  • Anxiety: may lessen anxiety symptoms in individuals with mild anxiety.

How It Works

  • Hypericum perforatum contains hypericin and hyperforin, which modulate central neurotransmitter activity. The extract inhibits the reuptake of serotonin, dopamine and norepinephrine, increasing their synaptic availability. Hyperforin also influences ion‑channel function and may affect the expression of neurotrophic factors, contributing to mood‑stabilising effects without direct receptor agonism.

Side Effects

Hypericum perforatum may be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: nausea, stomach cramps or diarrhea.
  • Photosensitivity: increased skin sensitivity to sunlight.
  • Dizziness or light‑headedness.
  • Fatigue or headache.

Serious or Rare Side Effects

  • Serotonin syndrome: risk when combined with other serotonergic agents.
  • Severe allergic reactions: rash, swelling, or anaphylaxis.
  • Hepatic dysfunction: abnormal liver enzymes or jaundice.

Precautions & Warnings

When considering Hypericum perforatum, several safety measures should be observed.

  • Pregnancy: safety not established; avoid unless benefits outweigh risks.
  • Breastfeeding: unknown safety; consider alternative therapies.
  • Drug interactions: review concomitant serotonergic medications before use.
  • Photosensitivity: advise patients to limit sun exposure and use protection.
  • Psychiatric monitoring: observe for mood swings or activation of mania.

Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Hypericum perforatum can affect the pharmacokinetics and pharmacodynamics of several medicines.

Major Interactions (Avoid)

  • SSRIs (e.g., fluoxetine, sertraline): risk of serotonin syndrome.
  • MAO inhibitors (e.g., phenelzine): heightened serotonergic activity.
  • Tricyclic antidepressants (e.g., amitriptyline): increased toxicity risk.
  • Anticoagulants (e.g., warfarin): reduced anticoagulant effect, increased bleeding risk.
  • Oral contraceptives: decreased plasma levels, possible contraceptive failure.

Moderate Interactions (Monitor Closely)

  • Antiepileptics (e.g., phenytoin): reduced serum concentrations.
  • Digoxin: possible decrease in drug levels.
  • Cyclosporine: lowered exposure, risk of organ rejection.

Frequently Asked Questions

Hypericum Nature's Bounty is an oral herbal product containing a dry extract of Hypericum perforatum. It is used to support the management of mild to moderate depression, seasonal affective disorder and anxiety in adult patients, acting as a natural antidepressant.

The active constituents hypericin and hyperforin modulate neurotransmitter activity by inhibiting the reuptake of serotonin, dopamine and norepinephrine. This increases the levels of these mood‑regulating chemicals in the brain, helping to improve depressive and anxious symptoms.

The appropriate dose of Hypericum Nature's Bounty is determined by the prescribing healthcare professional based on the individual’s condition, age, and response to therapy. Patients should follow the prescriber’s instructions and not alter the dose without medical advice.

Safety of Hypericum perforatum during pregnancy and lactation has not been established. It is generally advised to avoid use in pregnant or breastfeeding women unless the potential benefit justifies the possible risk, and only under medical supervision.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Unlike synthetic antidepressants, Hypericum Nature's Bounty is a plant‑derived preparation that primarily inhibits serotonin reuptake and modulates other neurotransmitters. It may have a more favorable side‑effect profile for some patients, but it also carries interaction risks, especially with other serotonergic drugs.

Store the product at ambient temperature, ideally below 25 °C. Keep it in the original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

Hypericum Nature's Bounty is taken orally, usually with water. The specific administration schedule—such as with or without food—should follow the prescriber’s guidance and the product label instructions.

The most serious concerns include the potential for serotonin syndrome when combined with other serotonergic agents, severe allergic reactions, and possible hepatic dysfunction. Patients should seek immediate medical attention if they experience symptoms such as rapid heart rate, high fever, confusion, rash, or jaundice.

Individuals taking monoamine oxidase inhibitors, selective serotonin reuptake inhibitors, tricyclic antidepressants, anticoagulants, or oral contraceptives should avoid Hypericum Nature's Bounty unless a healthcare professional advises otherwise. It is also contraindicated in pregnant or breastfeeding women without medical approval.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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