Product image of Hypnomidate (Etomidate) supplied by GNH India

Hypnomidate

Active Ingredient:
Etomidate
Origin:
EU

Hypnomidate (Etomidate)

Etomidate, the active ingredient in Hypnomidate, is a general anesthetic presented as a sterile injectable solution for intravenous use. It provides rapid induction of hypnosis and anesthesia, primarily for patients undergoing surgical procedures or requiring brief procedural sedation, and is used in adult and pediatric patients under professional supervision.

GNH India supplies Hypnomidate as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide, ensuring consistent quality, regulatory compliance and reliable supply chain management across global markets.

Manufacturer / TM Owner

Piramal Critical Care B.V.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Etomidate is a rapid‑acting general anesthetic that works through modulation of the GABA‑A receptor system, making it suitable for several procedural contexts.

  • Induction of general anesthesia: provides swift hypnosis for surgical procedures.
  • Sedation for short procedures: enables controlled sedation for diagnostic or minor interventions.
  • Emergency airway management: facilitates rapid sequence induction in critical care settings.
  • Maintenance of anesthesia: can be incorporated into balanced anesthesia regimens to sustain hypnosis.

How It Works

  • Etomidate acts as a positive modulator of the GABA‑A receptor, binding to the receptor complex and enhancing the inhibitory chloride current. This potentiation increases neuronal hyperpolarization, leading to rapid suppression of central nervous system activity, which produces hypnosis and anesthesia within seconds of intravenous administration.

Side Effects

Etomidate may cause a range of adverse reactions, from mild to severe. Awareness of these effects helps clinicians monitor patients appropriately.

Common Side Effects

  • Pain on injection.
  • Nausea or vomiting.
  • Transient hypotension.
  • Myoclonus or muscle twitching.

Serious or Rare Side Effects

  • Adrenal cortical suppression.
  • Severe hypotension or cardiovascular collapse.
  • Anaphylactic reaction.
  • Seizures or prolonged CNS depression.

Precautions & Warnings

When using Etomidate, several safety considerations should be observed to minimize risk.

  • Cardiovascular monitoring: observe blood pressure and heart rate during induction.
  • Respiratory support: be prepared for airway management and ventilation.
  • Adrenal function: consider risk of adrenal suppression in prolonged infusions.
  • Drug interactions: avoid concurrent use with other CNS depressants without supervision.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Etomidate can interact with other medications, requiring careful assessment before co‑administration.

Major Interactions (Avoid)

  • Concurrent use with other potent GABA‑A agonists (e.g., propofol, benzodiazepines) may cause profound respiratory depression.
  • Co‑administration with strong CYP3A4 inhibitors may increase Etomidate plasma concentrations.

Moderate Interactions (Monitor Closely)

  • Use with vasodilators may enhance hypotensive effects.
  • Combination with opioids may augment sedation and respiratory depression.
  • Concurrent use with corticosteroids may mask signs of adrenal suppression.

Frequently Asked Questions

Hypnomidate contains Etomidate, which is employed by clinicians to induce rapid general anesthesia for surgical procedures and to provide brief procedural sedation for diagnostic or minor interventions.

Etomidate positively modulates the GABA‑A receptor, increasing chloride ion flow into neurons. This enhances inhibitory neurotransmission, leading to quick suppression of central nervous system activity and resulting in hypnosis and anesthesia.

The dose of Hypnomidate is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and procedural requirements. Specific dosing regimens are not provided here.

Safety data for Etomidate in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and decisions should be made by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Compared with agents such as propofol, Etomidate provides hemodynamic stability with less impact on blood pressure, but it is associated with adrenal suppression and myoclonus. Choice of agent depends on the patient’s clinical profile and the anesthesiologist’s judgment.

Hypnomidate should be stored at ambient temperature, kept in its original packaging, protected from light and moisture, and used before the expiration date indicated on the label.

Hypnomidate is administered intravenously as a sterile solution. It is typically given as a rapid bolus injection under continuous monitoring of cardiovascular and respiratory parameters.

Serious risks include adrenal cortical suppression, severe hypotension or cardiovascular collapse, anaphylactic reactions, and seizures or prolonged central nervous system depression. Prompt recognition and supportive care are essential.

Hypnomidate is contraindicated in patients with known hypersensitivity to Etomidate or any formulation components, and it should be used with extreme caution in individuals with compromised adrenal function, severe cardiovascular instability, or uncontrolled epilepsy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Etomidate

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT