Product image of Hyrimoz (Adalimumab) supplied by GNH India

Hyrimoz

Active Ingredient:
Adalimumab
Origin:
EU

Hyrimoz (Adalimumab)

Adalimumab, the active ingredient in Hyrimoz, is a TNF inhibitor presented as a solution for injection for subcutaneous use. It treats several autoimmune inflammatory conditions in adults, including rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, and plaque psoriasis.

GNH India supplies Hyrimoz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sandoz Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Hyrimoz is a TNF‑alpha inhibitor used across a range of chronic inflammatory diseases.

  • Rheumatoid arthritis: reduces joint inflammation and slows disease progression.
  • Psoriatic arthritis: alleviates skin and joint symptoms and improves function.
  • Ankylosing spondylitis: decreases spinal inflammation and improves mobility.
  • Crohn's disease: induces and maintains remission of intestinal inflammation.
  • Ulcerative colitis: helps achieve remission and maintain symptom control.
  • Plaque psoriasis: clears skin lesions and reduces scaling.

How It Works

  • Adalimumab is a fully human monoclonal antibody that binds with high affinity to soluble and membrane‑bound tumor necrosis factor‑alpha (TNF‑α). By preventing TNF‑α from interacting with its cell‑surface receptors, the drug interrupts downstream inflammatory signaling pathways, thereby reducing the recruitment of immune cells and the production of pro‑inflammatory cytokines in affected tissues.

Side Effects

Adalimumab may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Injection site reactions: redness, swelling, or pain at the injection site.
  • Upper respiratory infections: common cold‑like symptoms.
  • Headache: mild to moderate intensity.
  • Rash: skin irritation or mild dermatitis.

Serious or Rare Side Effects

  • Serious infections: tuberculosis, fungal or bacterial infections.
  • Malignancies: increased risk of certain cancers such as lymphoma.
  • Demyelinating disorders: new or worsening neurologic symptoms.
  • Hepatitis B reactivation: flare of chronic hepatitis B infection.

Precautions & Warnings

Before initiating therapy, clinicians should assess patient history and monitor for adverse events.

  • Screen for active infections: test for tuberculosis and hepatitis before starting.
  • Monitor for signs of infection: advise patients to report fever or cough promptly.
  • Assess cardiac status: avoid in patients with moderate to severe heart failure.
  • Evaluate vaccination status: avoid live vaccines during treatment.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Adalimumab can interact with other immunomodulating agents and vaccines.

Major Interactions (Avoid)

  • Live vaccines: may cause severe infection; avoid concurrent use.
  • Concurrent TNF inhibitors: increased risk of immunosuppression.

Moderate Interactions (Monitor Closely)

  • Methotrexate: may enhance immunosuppressive effect.
  • Systemic corticosteroids: increased infection risk.
  • Azathioprine or cyclosporine: additive immunosuppression.
  • Antiviral therapy for hepatitis B: monitor for reactivation.

Frequently Asked Questions

Hyrimoz (adalimumab) is indicated for several autoimmune inflammatory diseases, including rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, plaque psoriasis, hidradenitis suppurativa, and non‑infectious uveitis. It works by reducing the inflammatory response that drives these conditions.

Adalimumab is a monoclonal antibody that specifically binds to tumor necrosis factor‑alpha (TNF‑α), a key cytokine in inflammation. By neutralising TNF‑α, it blocks the cascade of inflammatory signals, decreasing immune cell activation and reducing tissue damage in affected organs.

The dosage of Hyrimoz is individualized by the prescribing healthcare professional based on the specific indication, patient weight, and clinical response. Only a qualified prescriber can determine the appropriate dosing schedule and administration frequency.

Hyrimoz is classified as Pregnancy Category B, indicating no evidence of risk in animal studies but insufficient human data. It should only be used during pregnancy if the potential benefit justifies the potential risk. Breastfeeding mothers should discuss risks with their physician, as the drug may be present in breast milk.

To place an order, submit an enquiry on the Hyrimoz product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, cold‑chain shipping details, and necessary import documentation.

Hyrimoz (adalimumab) is a fully human monoclonal antibody, whereas alternatives like infliximab are chimeric antibodies and etanercept is a fusion protein. Adalimumab offers the convenience of subcutaneous self‑administration without the need for infusion, and its safety profile is comparable, though individual patient response may vary.

Hyrimoz should be stored in a refrigerator at 2‑8 °C (36‑46 °F). Keep the vial in its original packaging, protect it from light, and do not freeze or shake the solution. If temporary temperature excursions occur, consult the product label before use.

Hyrimoz is supplied as a solution for injection and is administered subcutaneously, typically in the thigh, abdomen, or upper arm. Patients are trained to use a pre‑filled syringe or autoinjector, and the injection site should be rotated to minimise local reactions.

The most serious risks include severe infections such as tuberculosis, opportunistic fungal or bacterial infections, reactivation of hepatitis B, malignancies (including lymphoma), and demyelinating neurological disorders. Patients should be monitored regularly for signs of infection or unusual symptoms.

Hyrimoz is contraindicated in patients with known hypersensitivity to adalimumab or any component of the formulation. It should also be avoided in individuals with active, severe infections, uncontrolled heart failure, or those receiving live vaccines. A thorough medical assessment is required before initiation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.