Product image of Iasoflu (Sodium Fluoride (18f)) supplied by GNH India

Iasoflu

Active Ingredient:
Sodium Fluoride (18f)
Origin:
EU

Iasoflu (Sodium Fluoride (18f))

Sodium Fluoride, the active ingredient in Iasoflu, is a Fluoride presented as an intravenous solution for intravenous use. It is employed to prevent dental caries and to provide systemic fluoride supplementation, particularly in individuals at risk of enamel demineralization such as children, adolescents, and adults with high caries susceptibility.

GNH India supplies Iasoflu as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing for healthcare providers who require a regulated fluoride product for preventive dental care programs.

Manufacturer / TM Owner

Curium Austria Gmbh

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Indications & Clinical Uses

Iasoflu (sodium fluoride) is used in the prevention of dental caries and for systemic fluoride supplementation.

  • Prevention of dental caries: Reduces incidence of new carious lesions by enhancing enamel resistance.
  • Fluoride supplementation: Increases systemic fluoride levels to support enamel remineralization in individuals with low dietary fluoride.
  • High‑risk patients: Provides therapeutic fluoride to children or adults prone to rapid enamel loss, aiding in caries control.

How It Works

  • After intravenous administration, sodium fluoride dissociates to release fluoride ions, which are incorporated into tooth enamel hydroxyapatite to form fluorapatite, a more acid‑resistant mineral. This process inhibits enamel demineralization and promotes remineralization, while also exerting antibacterial effects that reduce cariogenic bacterial activity in the oral cavity.

Side Effects

Adverse reactions may occur with intravenous sodium fluoride administration.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Vomiting: occasional emesis following infusion.
  • Abdominal pain: transient discomfort.
  • Metallic taste: brief metallic sensation in mouth.
  • Headache: mild headache during or after infusion.
  • Injection site pain: local discomfort at the infusion site.

Serious or Rare Side Effects

  • Fluoride toxicity: symptoms such as muscle weakness, tremors, or seizures.
  • Hypocalcemia: low blood calcium levels leading to cardiac arrhythmias.
  • Allergic reaction: rash, itching, or swelling.
  • Anaphylaxis: severe, life‑threatening hypersensitivity.
  • Renal impairment: worsening kidney function in susceptible patients.
  • Severe gastrointestinal upset: persistent vomiting or diarrhea.

Precautions & Warnings

When using Iasoflu, consider the following precautions.

  • Renal function: assess kidney performance as fluoride is renally cleared.
  • Pregnancy: prescribe only if potential benefit outweighs risk to the fetus.
  • Pediatric use: adjust dosing carefully for children and monitor fluoride exposure.
  • Concurrent fluoride sources: avoid excess total fluoride intake from supplements or fortified water.
  • Allergy: discontinue immediately if hypersensitivity signs appear.
  • Store at below 25°C: keep in the original container, protect from light and moisture.

Avoid Interactions

Iasoflu may interact with other medicines; monitor patients accordingly.

Major Interactions (Avoid)

  • Calcium supplements: can bind fluoride and reduce its effectiveness.
  • Vitamin D excess: may increase risk of fluoride toxicity.
  • Antacids containing aluminum or magnesium: may alter fluoride absorption.

Moderate Interactions (Monitor Closely)

  • Thyroid medications: fluoride may interfere with thyroid hormone synthesis.
  • Aminoglycoside antibiotics: potential additive nephrotoxicity.
  • Bisphosphonates: theoretical risk of altered bone metabolism when combined with fluoride.

Frequently Asked Questions

Iasoflu contains sodium fluoride and is prescribed to prevent dental caries and to provide systemic fluoride supplementation, especially for patients at high risk of enamel demineralization such as children, adolescents, and adults with low dietary fluoride intake.

Sodium fluoride releases fluoride ions that become incorporated into tooth enamel, forming fluorapatite, which is more resistant to acid attack. This strengthens enamel, reduces demineralization, and promotes remineralization while also inhibiting cariogenic bacteria.

The dosage of Iasoflu is determined by the prescribing healthcare professional based on the patient’s age, weight, renal function, and clinical need. Only a qualified prescriber should set the appropriate regimen.

Iasoflu should be used in pregnancy or while breastfeeding only if the potential benefit justifies any possible risk to the fetus or infant. The prescriber must evaluate the individual situation before deciding.

To order Iasoflu, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Iasoflu delivers fluoride intravenously, offering rapid systemic exposure compared with oral fluoride tablets or topical gels that rely on gastrointestinal absorption or local application. This route can be advantageous for patients who cannot take oral medications or need immediate fluoride levels, but it requires medical supervision.

Store Iasoflu at below 25 °C in its original packaging, protecting it from light and moisture. Do not freeze the solution, and keep it out of reach of children.

Iasoflu is administered by intravenous infusion under the supervision of qualified healthcare personnel. The infusion rate and duration are set by the prescriber and nursing staff according to the patient’s clinical condition.

Serious risks include fluoride toxicity, which can manifest as muscle weakness, seizures, or cardiac arrhythmias, as well as severe allergic reactions such as anaphylaxis. Monitoring of calcium levels and renal function is essential during therapy.

Iasoflu should be avoided in patients with known hypersensitivity to sodium fluoride, severe renal impairment, uncontrolled electrolyte abnormalities, or in those who have received excessive fluoride from other sources. The prescriber must assess contraindications before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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