Product image of Ibenal (Ibuprofen) supplied by GNH India

Ibenal

Active Ingredient:
Ibuprofen
Origin:
EU

Ibenal (Ibuprofen)

Ibuprofen, the active ingredient in Ibenal, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It treats pain, fever and inflammation in adults and children as directed by a healthcare professional.

GNH India supplies Ibenal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Przedsiębiorstwo Farmaceutyczne Lek-Am Sp. Z O.O.

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Indications & Clinical Uses

  • Ibuprofen is an NSAID that reduces pain, fever and inflammation by inhibiting prostaglandin synthesis.
  • Pain: provides relief of mild to moderate acute or chronic pain
  • Fever: lowers elevated body temperature in febrile states
  • Inflammation: decreases swelling associated with inflammatory conditions
  • Arthritis: alleviates joint pain and stiffness in osteoarthritis and rheumatoid arthritis

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2. This inhibition blocks the conversion of arachidonic acid to prostaglandins, thereby reducing the mediators responsible for pain, fever and inflammation throughout the body.

Side Effects

Common Side Effects

  • Gastrointestinal upset (nausea, dyspepsia)
  • Headache
  • Dizziness
  • Mild skin rash
  • Diarrhoea
  • Flatulence

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding
  • Severe allergic reactions (anaphylaxis, angioedema)
  • Acute renal impairment
  • Hepatic injury
  • Cardiovascular thrombotic events
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis

Precautions & Warnings

Before using Ibenal, consider the following precautions:

  • Assess renal function: evaluate kidney status prior to initiation
  • Monitor gastrointestinal risk: avoid in patients with a history of ulcer disease
  • Use the lowest effective dose: limit duration to reduce adverse events
  • Avoid in third‑trimester pregnancy: contraindicated due to fetal risks
  • Caution with anticoagulants: increased risk of bleeding
  • Store at ambient temperature: keep in the original container, protect from moisture and heat

Avoid Interactions

Ibuprofen can interact with several medicines. Review the following before co‑administration.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk
  • Other NSAIDs: additive gastrointestinal toxicity
  • Corticosteroids: increased ulcer risk
  • ACE inhibitors or ARBs: potential reduction in renal function
  • Lithium: elevated serum lithium concentrations

Moderate Interactions (Monitor Closely)

  • Diuretics: possible renal effects
  • Methotrexate: reduced clearance leading to toxicity
  • SSRIs: increased bleeding tendency
  • Beta‑blockers: may blunt antihypertensive response
  • Cyclosporine: enhanced nephrotoxicity

Frequently Asked Questions

Ibenal contains ibuprofen, an NSAID indicated for the relief of mild to moderate pain, reduction of fever, and mitigation of inflammation associated with conditions such as arthritis, musculoskeletal injuries, and postoperative discomfort.

Ibuprofen works by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which decreases the synthesis of prostaglandins—key mediators that promote pain, fever, and inflammation in the body.

The appropriate dose of Ibenal is determined by the prescribing healthcare professional based on the patient’s age, condition, and response. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Ibuprofen is generally avoided in the third trimester of pregnancy because of potential fetal risks. Use during earlier stages or while breastfeeding should be discussed with a healthcare provider, who can weigh benefits against possible risks.

To order Ibenal, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Both Ibenal (ibuprofen) and naproxen belong to the NSAID class and share similar mechanisms of COX inhibition. Ibuprofen generally has a shorter half‑life, requiring more frequent dosing, while naproxen provides longer‑lasting relief but may have a higher risk of gastrointestinal irritation in some patients.

Store Ibenal at ambient temperature, below 25 °C, in its original packaging. Protect the tablets from moisture, direct sunlight and excessive heat to maintain product stability throughout its shelf life.

Ibenal is taken orally with a full glass of water. It can be taken with or without food, although taking it with food may reduce the likelihood of gastrointestinal discomfort.

Serious risks include gastrointestinal ulceration or bleeding, severe allergic reactions such as anaphylaxis, acute kidney injury, liver toxicity, and an increased chance of cardiovascular events like heart attack or stroke, especially with prolonged use or high doses.

Ibenal should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulceration, severe renal or hepatic impairment, and pregnant women in the third trimester. Patients on certain anticoagulants or with uncontrolled hypertension should also consult a physician before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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