Product image of Ibenal (Ibuprofen) supplied by GNH India

Ibenal

Active Ingredient:
Ibuprofen
Origin:
EU

Ibenal (Ibuprofen)

Ibuprofen, the active ingredient in Ibenal, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a suppository for rectal use. It provides pain relief, reduces fever, and alleviates inflammation in adults and children when oral administration is unsuitable.

GNH India supplies Ibenal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Przedsiębiorstwo Farmaceutyczne Lek-Am Sp. Z O.O.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Ibuprofen is an NSAID that reduces inflammation and pain by inhibiting prostaglandin synthesis.

  • Pain relief: alleviates mild to moderate pain such as headache, dental pain, and musculoskeletal discomfort.
  • Fever reduction: lowers elevated body temperature in febrile conditions.
  • Inflammation control: decreases swelling associated with sprains, strains, and inflammatory joint conditions.

How It Works

  • Ibuprofen inhibits both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which are essential for converting arachidonic acid into prostaglandins. By reducing prostaglandin synthesis, it diminishes peripheral sensitization, lowers fever set‑points in the hypothalamus, and limits inflammatory exudate formation, resulting in analgesic, antipyretic, and anti‑inflammatory effects.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Gastrointestinal discomfort: mild stomach upset or dyspepsia.
  • Nausea: transient feeling of queasiness.
  • Headache: mild to moderate head pain.
  • Dizziness: occasional light‑headed sensation.
  • Local rectal irritation: mild burning or itching at the site of administration.
  • Diarrhoea: loose stools in some users.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Renal impairment or reduced kidney function.
  • Severe allergic reactions such as anaphylaxis.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Hepatic injury: elevated liver enzymes or hepatitis.
  • Cardiovascular events: increased risk of thrombotic complications.

Precautions & Warnings

Before using Ibenal, consider the following safety measures.

  • Renal function: assess kidney health, especially in patients with chronic renal disease.
  • Cardiovascular risk: use cautiously in individuals with known heart disease or hypertension.
  • Gastro‑intestinal history: avoid in patients with active ulcers or a history of serious GI bleeding.
  • Hypersensitivity: discontinue if signs of allergic reaction appear.
  • Pregnancy and lactation: consult a healthcare professional; safety data are limited.
  • Store at ambient temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: heightened risk of ulceration.
  • ACE inhibitors or ARBs: possible reduction in renal function.
  • Lithium: elevated lithium serum levels.

Moderate Interactions (Monitor Closely)

  • Diuretics: potential decrease in antihypertensive effect.
  • Methotrexate: reduced clearance leading to toxicity.
  • SSRIs: modest increase in bleeding tendency.
  • Antihypertensives: possible attenuation of blood‑pressure control.
  • Allopurinol: rare reports of enhanced skin reactions.

Frequently Asked Questions

Ibenal is a rectal suppository containing ibuprofen, an NSAID that provides analgesic, antipyretic, and anti‑inflammatory effects. It is commonly used to relieve mild to moderate pain, lower fever, and reduce swelling when oral tablets are not suitable or preferred.

Ibuprofen works by inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are responsible for producing prostaglandins. Lower prostaglandin levels diminish inflammation, lower the hypothalamic set‑point for temperature, and reduce the sensitization of pain receptors, resulting in pain relief and fever reduction.

The appropriate dose of Ibenal is determined by a prescriber based on the patient’s age, weight, clinical condition, and response to therapy. Healthcare professionals select the strength and frequency that best address the individual’s therapeutic needs.

Safety data for ibuprofen suppositories in pregnancy and lactation are limited. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks with their healthcare provider before using Ibenal, as alternative treatments may be recommended.

To place an order, submit an enquiry on the Ibenal product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Ibenal offers the same active ingredient as oral ibuprofen tablets but in a rectal suppository form, which can be advantageous for patients who cannot swallow tablets or have gastrointestinal irritation from oral NSAIDs. The pharmacological profile is comparable, while the route of administration may affect onset and local tolerability.

Store Ibenal at ambient temperature, preferably below 25 °C. Keep the suppositories in their original packaging, protect them from moisture, heat, and direct sunlight to maintain product stability and efficacy.

Ibenal is inserted rectally, typically using a gloved finger or an applicator if provided. The suppository should be placed gently into the rectum, preferably after a bowel movement, and the patient should remain lying down for a few minutes to ensure proper absorption.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, renal impairment, and rare skin conditions like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience symptoms such as vomiting blood, severe abdominal pain, rash, or difficulty breathing.

Ibenal should be avoided by individuals with known hypersensitivity to ibuprofen or any other NSAIDs, those with active gastrointestinal ulcers, severe renal or hepatic impairment, and patients in the third trimester of pregnancy unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Ibuprofen

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT