Product image of Ibifen (Ketoprofen) supplied by GNH India

Ibifen

Active Ingredient:
Ketoprofen
Origin:
EU

Ibifen (Ketoprofen)

Ketoprofen, the active ingredient in Ibifen, is a nonsteroidal anti‑inflammatory drug presented as an oral formulation for systemic use. It is employed to relieve mild to moderate pain and to reduce inflammation associated with musculoskeletal disorders, arthritis and other inflammatory conditions in adult patients.

GNH India supplies Ibifen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and other health‑care institutions worldwide. The company emphasizes quality assurance, regulatory compliance and reliable global logistics to ensure product integrity through certified manufacturing processes.

Manufacturer / TM Owner

Ibi G. Lorenzini Spa

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Ketoprofen is an NSAID that reduces inflammation and pain by inhibiting cyclooxygenase enzymes.

  • Rheumatoid arthritis: decreases joint pain and swelling.
  • Osteoarthritis: improves mobility and reduces chronic joint discomfort.
  • Acute musculoskeletal injury: alleviates pain and inflammation associated with sprains, strains and soft‑tissue trauma.

How It Works

  • Ketoprofen reversibly inhibits both COX‑1 and COX‑2 enzymes, leading to a decrease in prostaglandin synthesis. This reduction diminishes inflammation, pain signaling, and fever responses at sites of tissue injury, providing analgesic and anti‑inflammatory effects throughout the body.

Side Effects

Ketoprofen may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Gastrointestinal upset: dyspepsia, nausea, or abdominal discomfort.
  • Headache or dizziness.
  • Skin rash or mild itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Renal impairment or reduced kidney function.
  • Severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome.
  • Hepatotoxicity leading to elevated liver enzymes.
  • Blood dyscrasias including thrombocytopenia.

Precautions & Warnings

Before using Ibifen, consider the following safety measures.

  • Assess renal function: evaluate kidney status prior to initiation.
  • Monitor gastrointestinal risk: avoid in patients with a history of ulcers or bleeding.
  • Avoid concurrent NSAIDs: reduce additive risk of gastrointestinal toxicity.
  • Use lowest effective dose: limit duration to the shortest period necessary.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Ketoprofen can interact with several medicines; awareness helps minimize risk.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Selective COX‑2 inhibitors: additive gastrointestinal toxicity.
  • Lithium: potential rise in serum lithium levels.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: possible decline in renal function.
  • Diuretics: may affect potassium balance and kidney health.
  • Methotrexate: reduced clearance leading to higher systemic exposure.

Frequently Asked Questions

Ibifen contains ketoprofen, an NSAID indicated for the relief of mild to moderate pain and for reducing inflammation in conditions such as rheumatoid arthritis, osteoarthritis, and acute musculoskeletal injuries. It is prescribed for adults who need anti‑inflammatory and analgesic therapy.

Ketoprofen works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for prostaglandin production. Lower prostaglandin levels lead to decreased inflammation, pain signaling, and fever, providing both analgesic and anti‑inflammatory effects throughout the body.

The appropriate dose of Ibifen is determined by a qualified prescriber based on the patient’s condition, age, weight, and overall health. Healthcare professionals will select the strength, frequency, and duration that best suit the individual’s therapeutic needs.

Safety of ketoprofen in pregnancy and lactation has not been definitively established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and this decision must be made by a healthcare professional.

To order Ibifen, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ketoprofen (Ibifen) generally offers a longer duration of action compared with ibuprofen, which may allow for less frequent dosing. Both belong to the same NSAID class and share similar mechanisms, but ketoprofen can be slightly more potent in reducing inflammation, while individual response and safety profiles vary.

Ibifen should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in bathrooms or other humid environments.

Ibifen is taken orally, usually with a full glass of water. It can be taken with or without food, but taking it with food may reduce the likelihood of gastrointestinal discomfort. Follow the prescriber’s instructions regarding timing and any required meals.

The most serious risks include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome, and renal impairment that can affect kidney function. Patients should seek immediate medical attention if they experience symptoms like black stools, severe abdominal pain, rash, or swelling.

Ibifen should be avoided by individuals with known hypersensitivity to ketoprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or significant renal or hepatic impairment. Pregnant women in the third trimester and patients on certain anticoagulants should also consult a physician before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.