Product image of Ibitred (Colecalciferol) supplied by GNH India

Ibitred

Active Ingredient:
Colecalciferol
Origin:
EU

Ibitred (Colecalciferol)

Colecalciferol, the active ingredient in Ibitred, is a Vitamin D presented as an oral supplement for oral use. It treats vitamin D deficiency and related bone disorders in individuals requiring supplementation.

GNH India supplies Ibitred as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ibi G. Lorenzini Spa

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Indications & Clinical Uses

Ibitred is a vitamin D supplement used to correct deficiencies and support bone health.

  • Vitamin D deficiency: restores normal serum 25‑hydroxyvitamin D levels.
  • Osteomalacia: promotes bone mineralization and reduces bone pain.
  • Rickets: aids in proper bone development in children.

How It Works

  • Colecalciferol is converted in the liver to 25‑hydroxyvitamin D and subsequently in the kidney to the active hormone 1,25‑dihydroxyvitamin D. This active form binds to vitamin D receptors in intestinal cells, enhancing transcription of calcium‑binding proteins, which increases intestinal absorption of calcium and phosphate and supports bone mineralization.

Side Effects

Adverse reactions may occur with oral vitamin D supplementation.

Common Side Effects

  • Hypercalcemia: elevated blood calcium levels.
  • Nausea: mild gastrointestinal upset.
  • Constipation: reduced bowel movements.
  • Dry mouth: reduced salivary flow.
  • Headache: mild to moderate head pain.
  • Fatigue: feeling of tiredness.

Serious or Rare Side Effects

  • Hypercalciuria: excessive urinary calcium excretion.
  • Kidney stones: formation of calcium‑based calculi.
  • Severe hypercalcemia: may cause cardiac arrhythmia.
  • Allergic reactions: rash, itching, swelling.
  • Anaphylaxis: rare, life‑threatening hypersensitivity.

Precautions & Warnings

Vitamin D supplementation requires careful consideration of patient factors and proper handling.

  • Monitor serum calcium: check levels before and during therapy.
  • Assess baseline vitamin D status: measure 25‑hydroxyvitamin D.
  • Adjust dose in renal impairment: reduce to avoid accumulation.
  • Avoid concurrent high‑dose calcium supplements: risk of hypercalcemia.
  • Use caution in sarcoidosis or granulomatous diseases: increased conversion to active form.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Vitamin D can interact with several medicines, affecting calcium balance or vitamin D metabolism.

Major Interactions (Avoid)

  • Thiazide diuretics: increase risk of hypercalcemia.
  • High‑dose calcium carbonate: may cause excessive calcium levels.
  • Vitamin A excess: potentiates toxicity.
  • Alendronate: may reduce absorption of vitamin D.
  • Rifampicin: accelerates vitamin D catabolism.

Moderate Interactions (Monitor Closely)

  • Anticonvulsants (phenytoin, phenobarbital): lower vitamin D levels.
  • Glucocorticoids: impair vitamin D activity.
  • Cholestyramine: reduces absorption of fat‑soluble vitamins.
  • Orlistat: decreases vitamin D uptake.
  • Loop diuretics: increase calcium excretion, may require monitoring.

Frequently Asked Questions

Ibitred contains colecalciferol, a form of vitamin D, and is used to treat vitamin D deficiency and related bone conditions such as osteomalacia and rickets by restoring normal serum vitamin D levels.

Colecalciferol is converted in the liver and kidneys to the active hormone 1,25‑dihydroxyvitamin D, which binds to vitamin D receptors in the intestine, increasing the synthesis of calcium‑binding proteins and thereby enhancing calcium and phosphate absorption for bone mineralization.

The appropriate dose of Ibitred is determined by the prescribing healthcare professional based on the patient’s serum vitamin D level, age, weight, and clinical condition. Patients should follow the prescriber’s instructions and not self‑adjust the dose.

Vitamin D supplementation is generally considered safe during pregnancy and lactation when prescribed by a healthcare provider. However, patients should discuss any use of Ibitred with their obstetrician or pediatrician to ensure appropriate dosing.

To order Ibitred, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibitred provides colecalciferol in an oral dosage form that meets EU quality standards. Compared with other vitamin D preparations, it offers consistent potency, GMP‑compliant manufacturing, and is available as an over‑the‑counter product, making it suitable for a broad range of patients.

Ibitred should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight and excessive heat to maintain its stability and potency.

Ibitred is taken orally, usually with water. The exact administration schedule—such as frequency and timing relative to meals—should follow the prescribing clinician’s guidance.

The most serious risks include hypercalcemia, hypercalciuria, kidney stone formation, and rare severe allergic reactions. Patients should be monitored for symptoms such as persistent nausea, vomiting, weakness, or unexplained pain and report them promptly.

Ibitred should be avoided in individuals with known hypersensitivity to colecalciferol or any excipients, patients with severe hypercalcemia, and those with conditions that cause excessive conversion of vitamin D to its active form, such as sarcoidosis, unless directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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