Product image of Ibu - 1 A Pharma Grippal (Pseudoephedrine Hydrochloride, Ibuprofen) supplied by GNH India

Ibu - 1 A Pharma Grippal

Active Ingredient:
Pseudoephedrine Hydrochloride, Ibuprofen
Origin:
EU

Ibu - 1 A Pharma Grippal (Pseudoephedrine Hydrochloride, Ibuprofen)

Ibuprofen and pseudoephedrine hydrochloride, the active ingredients in Ibu - 1 A Pharma Grippal, are a nonsteroidal anti‑inflammatory drug and a sympathomimetic decongestant presented as a tablet for oral use. They relieve mild to moderate pain, fever and nasal congestion in adults.
GNH India supplies Ibu - 1 A Pharma Grippal as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

1 A Pharma Gmbh

1
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Indications & Clinical Uses

Ibu - 1 A Pharma Grippal combines an NSAID and a nasal decongestant to address common cold‑related symptoms and pain.

  • Nasal congestion: reduction of swelling in nasal mucosa to improve airflow.
  • Headache, musculoskeletal pain or toothache: alleviation of pain and inflammation.
  • Fever: lowering of elevated body temperature associated with viral or bacterial infections.

How It Works

  • Ibuprofen inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, decreasing prostaglandin synthesis and thereby reducing inflammation, pain and fever. Pseudoephedrine hydrochloride acts as an α‑adrenergic agonist, causing vasoconstriction of nasal mucosal vessels, which diminishes edema and relieves congestion.

Side Effects

Common Side Effects

  • Nausea or upset stomach.
  • Headache.
  • Dizziness or light‑headedness.
  • Insomnia.
  • Increased blood pressure.
  • Mild rash.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome.
  • Marked hypertension or cardiac arrhythmia.
  • Liver injury.
  • Severe skin reactions.
  • Acute kidney injury.

Precautions & Warnings

Before using Ibu - 1 A Pharma Grippal, consider the following precautions:

  • Pregnancy: consult a healthcare professional before use.
  • Cardiovascular disease: use with caution due to possible blood‑pressure elevation.
  • History of gastrointestinal ulcer or bleeding: avoid or monitor closely.
  • Renal impairment: monitor kidney function and adjust use if needed.
  • Concomitant medications: review potential drug interactions with a pharmacist or physician.
  • Store at ambient temperature: keep in the original packaging, protect from moisture and heat.

Avoid Interactions

Ibu - 1 A Pharma Grippal may interact with several medicines.

Major Interactions (Avoid)

  • Warfarin or other anticoagulants: increased risk of bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: possible reduction of decongestant effect.
  • Diuretics: may enhance hypotensive response.
  • Lithium: pseudoephedrine can raise lithium serum levels.

Frequently Asked Questions

Ibu - 1 A Pharma Grippal is an over‑the‑counter combination of ibuprofen and pseudoephedrine that provides relief from mild to moderate pain, reduces fever, and eases nasal congestion associated with colds, sinusitis or allergic rhinitis in adults.

Ibuprofen blocks the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which lowers prostaglandin production. This action reduces inflammation, diminishes pain signals, and helps bring down fever. Pseudoephedrine adds a decongestant effect by narrowing blood vessels in the nasal passages.

The appropriate dose is determined by the prescribing healthcare professional based on the individual’s age, weight, medical condition and other medications. Patients should follow the prescriber’s instructions and the product label without exceeding the recommended amount.

Safety data for this combination in pregnancy and lactation are limited. Women who are pregnant, planning pregnancy, or breastfeeding should consult their physician before using the product to weigh potential benefits against risks.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Compared with acetaminophen‑based products, the ibuprofen component offers stronger anti‑inflammatory activity, while the pseudoephedrine adds nasal decongestion. This makes the combination useful for cold‑related pain and congestion, whereas acetaminophen alone does not address nasal swelling.

Store the tablets at ambient temperature, preferably below 25 °C. Keep them in the original container, protect from moisture and direct sunlight, and keep out of reach of children.

The product is taken orally with a full glass of water. It may be taken with or without food, although taking it with food can reduce stomach irritation. Swallow the tablet whole; do not crush or chew.

Serious risks include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome, marked hypertension, and rare but serious kidney or liver injury. Seek immediate medical attention if any of these occur.

Individuals with known hypersensitivity to ibuprofen, pseudoephedrine, or any component of the tablet should avoid it. It is also contraindicated in patients with active peptic ulcer disease, severe uncontrolled hypertension, certain heart conditions, and in the third trimester of pregnancy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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