Product image of Ibu 800 Ret (Ibuprofen) supplied by GNH India

Ibu 800 Ret

Active Ingredient:
Ibuprofen
Origin:
EU

Ibu 800 Ret (Ibuprofen)

Ibuprofen, the active ingredient in Ibu 800 Ret, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It is used to relieve mild to moderate pain, reduce fever, and manage inflammation associated with conditions such as osteoarthritis and rheumatoid arthritis.

GNH India supplies Ibu 800 Ret as a licensed, GDP‑compliant international pharmaceutical supplier, delivering the product through regulated distribution channels to hospitals, pharmacies and clinics worldwide throughout, ensuring quality assurance and compliance with EU standards.

Manufacturer / TM Owner

1 A Pharma Gmbh

1
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Indications & Clinical Uses

Ibuprofen acts on inflammatory pathways to provide analgesic, antipyretic and anti‑inflammatory effects.

  • Mild to moderate pain: reduces pain perception by inhibiting prostaglandin synthesis.
  • Fever: lowers elevated body temperature through central action on the hypothalamic set point.
  • Osteoarthritis: alleviates joint pain and improves mobility.
  • Rheumatoid arthritis: decreases inflammation and pain in affected joints.
  • General inflammation: reduces swelling and redness in various inflammatory conditions.

How It Works

  • Ibuprofen exerts its pharmacological action by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes. This inhibition decreases the conversion of arachidonic acid to prostaglandins and thromboxanes, leading to reduced synthesis of mediators that cause pain, fever and inflammation. The reduced prostaglandin levels also diminish peripheral sensitization of nociceptors and central fever signaling.

Side Effects

Adverse reactions to ibuprofen may range from mild to severe and should be monitored during therapy.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness: transient sensation of light‑headedness.
  • Rash: mild skin erythema or itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: ulceration or hemorrhage in the stomach or intestines.
  • Renal impairment: sudden decrease in kidney function or elevated creatinine.
  • Severe allergic reactions: anaphylaxis, angioedema or bronchospasm.
  • Hepatotoxicity: marked elevation of liver enzymes or hepatitis.

Precautions & Warnings

Before prescribing Ibu 800 Ret, clinicians should consider several safety factors.

  • Assess renal function: avoid use in patients with severe kidney disease.
  • Evaluate gastrointestinal risk: use with caution in those with a history of ulcers or bleeding.
  • Monitor cardiovascular status: consider risk in patients with hypertension or heart disease.
  • Use during pregnancy only if clearly needed: consult obstetric guidance.
  • Store at ambient temperature below 25°C: keep in original packaging, protect from moisture and light.

Avoid Interactions

Ibuprofen can interact with a range of medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or corticosteroids: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding potential.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or diuretics: may reduce renal perfusion.
  • Lithium: ibuprofen can raise lithium serum levels.

Frequently Asked Questions

Ibu 800 Ret contains ibuprofen, a prescription NSAID that is commonly prescribed to relieve mild‑to‑moderate pain, lower fever, and reduce inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis and other inflammatory disorders.

Ibuprofen works by non‑selectively blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are required for the conversion of arachidonic acid into prostaglandins. By lowering prostaglandin production, it diminishes pain signals, reduces fever, and limits inflammatory swelling.

The exact dosage of Ibu 800 Ret is determined by the prescribing clinician based on the patient’s age, weight, medical condition and response to therapy. Healthcare professionals adjust the amount and frequency to achieve optimal pain or fever control while minimizing risk.

Ibuprofen is generally avoided in the third trimester of pregnancy because of potential fetal cardiovascular effects, and it should only be used during pregnancy or lactation when clearly indicated and under medical supervision. Patients should discuss risks with their obstetrician or pediatrician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibu 800 Ret delivers ibuprofen, which offers a balance of analgesic, antipyretic and anti‑inflammatory activity and has a relatively short half‑life compared with some NSAIDs such as naproxen. Its efficacy is comparable, while its safety profile, especially gastrointestinal risk, is similar to other non‑selective NSAIDs.

The product should be stored at ambient temperature below 25 °C, in its original packaging, protected from moisture, heat and direct sunlight. Keeping the tablets in a dry, sealed container helps maintain potency throughout the shelf‑life.

Ibu 800 Ret is taken orally, usually with a full glass of water. It may be taken with or without food, although taking it with meals can lessen gastrointestinal discomfort. Patients should follow the prescriber’s instructions regarding timing and frequency.

The most serious adverse events include gastrointestinal bleeding or ulceration, severe renal impairment, and hypersensitivity reactions such as anaphylaxis. Patients experiencing black stools, sudden loss of kidney function, or signs of an allergic reaction should seek immediate medical attention.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcer disease, severe renal or hepatic impairment, uncontrolled hypertension, or those in the third trimester of pregnancy should avoid using Ibu 800 Ret unless specifically directed by a qualified healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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