Product image of Ibu-Lysin - 1 A Pharma (Ibuprofen) supplied by GNH India

Ibu-Lysin - 1 A Pharma

Active Ingredient:
Ibuprofen
Origin:
EU

Ibu-Lysin - 1 A Pharma (Ibuprofen)

Ibuprofen, the active ingredient in Ibu-Lysin, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It is used to relieve pain, reduce fever, and diminish inflammation associated with conditions such as arthritis in adults and, when appropriate, in pediatric patients.

GNH India supplies Ibu-Lysin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for global healthcare providers through established distribution networks.

Manufacturer / TM Owner

1 A Pharma Gmbh

1
Pack/s
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Indications & Clinical Uses

  • Ibuprofen acts on the cyclooxygenase pathway to alleviate symptoms in several common conditions.
  • Pain: Reduces mild to moderate pain.
  • Fever: Lowers elevated body temperature.
  • Inflammation: Decreases swelling and redness.
  • Arthritis: Improves joint mobility and reduces chronic inflammation.

How It Works

  • Ibuprofen exerts its effect by reversibly inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are key in the conversion of arachidonic acid to prostaglandins. By reducing prostaglandin synthesis, it diminishes the inflammatory response, lowers fever, and blunts pain signaling at peripheral nerve endings. The inhibition is dose‑dependent and occurs throughout the body, providing systemic anti‑inflammatory and analgesic activity without affecting the central nervous system directly.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain.
  • Headache: mild to moderate headache.
  • Dizziness: transient feeling of light‑headedness.
  • Rash: mild skin irritation or itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: ulceration or hemorrhage in the stomach or intestines.
  • Renal impairment: reduced kidney function or acute kidney injury.
  • Severe allergic reaction: anaphylaxis, swelling of face or throat.

Precautions & Warnings

  • When using ibuprofen, certain precautions should be observed to minimize risk.
  • Assess renal function: avoid use in patients with severe kidney disease.
  • Monitor cardiovascular risk: use cautiously in individuals with heart disease or hypertension.
  • Avoid concurrent NSAIDs: do not combine with other non‑steroidal anti‑inflammatory drugs.
  • Limit alcohol intake: excessive alcohol may increase gastrointestinal toxicity.
  • Store at ambient temperature: keep below 25 °C in the original packaging, protected from moisture.

Avoid Interactions

Ibuprofen can interact with several medicines, altering their effectiveness or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce antihypertensive effect and impair renal function.
  • Lithium: ibuprofen can raise lithium levels, requiring monitoring.
  • Methotrexate: reduced clearance may increase toxicity.

Frequently Asked Questions

Ibu-Lysin contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, reduce fever, and lessen inflammation. It is indicated for conditions such as headache, dental pain, musculoskeletal discomfort, fever associated with infections, and inflammatory disorders like osteoarthritis and rheumatoid arthritis.

Ibuprofen works by reversibly blocking the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for converting arachidonic acid into prostaglandins. Prostaglandins mediate pain, fever, and inflammation, so their reduced production leads to analgesic, antipyretic, and anti‑inflammatory effects throughout the body.

The appropriate dose of Ibu-Lysin is determined by a qualified prescriber based on the patient’s age, weight, medical condition, and response to therapy. Healthcare professionals consider factors such as severity of symptoms, renal and hepatic function, and potential drug interactions before recommending a specific dosing regimen.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and individual risk factors. Generally, ibuprofen is avoided in the third trimester because of potential fetal cardiovascular effects. During breastfeeding, small amounts may pass into milk, so a healthcare provider should evaluate the risk‑benefit ratio before use.

To order Ibu-Lysin, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the sales team provides pricing, availability, shipping details and any necessary import documentation.

Ibu-Lysin (ibuprofen) shares the core anti‑inflammatory and analgesic properties of the NSAID class, but its potency, half‑life, and gastrointestinal safety profile differ from agents such as naproxen or diclofenac. Ibuprofen has a relatively short half‑life, allowing flexible dosing, and is often preferred for short‑term pain and fever management.

Ibu-Lysin should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability throughout its shelf life.

Ibu-Lysin is taken orally, usually with a full glass of water. It may be taken with or without food; however, taking it with food can reduce the likelihood of stomach irritation. The exact administration schedule is determined by the prescribing clinician.

Serious risks include gastrointestinal bleeding or ulceration, especially with prolonged use or in patients with a history of ulcers. Renal impairment can occur, particularly in individuals with pre‑existing kidney disease or dehydration. Rarely, severe allergic reactions such as anaphylaxis may develop, requiring immediate medical attention.

Ibu-Lysin should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding, severe heart failure, or advanced renal or hepatic impairment. It is also contraindicated in patients who have had recent coronary artery bypass graft surgery or who are taking certain anticoagulants without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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