Product image of Ibu-Lysin Al (Ibuprofen) supplied by GNH India

Ibu-Lysin Al

Active Ingredient:
Ibuprofen
Origin:
EU

Ibu-Lysin Al (Ibuprofen)

Ibuprofen, the active ingredient in Ibu-Lysin Al, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It is employed to relieve mild to moderate pain, reduce fever, and manage inflammatory conditions such as osteoarthritis and rheumatoid arthritis in adult patients across the European market.

GNH India supplies Ibu-Lysin Al as a licensed, GDP‑compliant international pharmaceutical product to hospitals, pharmacies and clinics worldwide, adhering to stringent quality standards and offering reliable global distribution.

Manufacturer / TM Owner

Aliud Pharma Gmbh

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Indications & Clinical Uses

Ibu-Lysin Al, an NSAID, acts on prostaglandin-mediated pathways to alleviate symptoms of several common conditions.

  • Pain: provides relief of mild to moderate acute pain.
  • Fever: reduces elevated body temperature.
  • Osteoarthritis: eases joint pain and inflammation.
  • Rheumatoid arthritis: helps control inflammatory symptoms.
  • Dental pain: alleviates discomfort associated with dental procedures.

How It Works

  • Ibuprofen reversibly inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. This reduction in prostaglandin synthesis diminishes inflammation, lowers fever, and lessens pain perception at peripheral and central sites.

Side Effects

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort.
  • Headache: mild to moderate intensity.
  • Dizziness: transient sensation of light‑headedness.
  • Rash: mild skin irritation or erythema.
  • Elevated liver enzymes: occasional mild increase in hepatic markers.
  • Fluid retention: mild peripheral edema.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Severe renal impairment or acute kidney injury.
  • Anaphylaxis or severe allergic reactions.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Hepatotoxicity with marked liver enzyme elevation.
  • Cardiovascular events such as myocardial infarction in high‑risk patients.

Precautions & Warnings

Before initiating therapy, consider the following precautions:

  • Assess renal function: adjust use in patients with existing kidney disease.
  • Review gastrointestinal history: avoid in active ulcer disease or recent GI bleeding.
  • Evaluate bleeding risk: use cautiously with anticoagulants or antiplatelet agents.
  • Monitor asthma status: ibuprofen may precipitate bronchospasm in susceptible individuals.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Ibuprofen may interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Selective COX‑2 inhibitors: additive gastrointestinal toxicity.
  • Lithium: potential elevation of lithium serum concentrations.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal function, especially in volume‑depleted patients.
  • Diuretics: heightened risk of renal impairment.
  • Methotrexate: possible increase in methotrexate toxicity.
  • SSRIs or SNRIs: may modestly raise bleeding tendency.
  • Corticosteroids: combined use can exacerbate gastrointestinal ulcer risk.

Frequently Asked Questions

Ibu-Lysin Al contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, reduce fever, and treat inflammatory conditions such as osteoarthritis, rheumatoid arthritis, and dental pain. It is indicated for adult patients who need symptomatic relief from these conditions.

Ibuprofen works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for the conversion of arachidonic acid into prostaglandins. By lowering prostaglandin levels, ibuprofen reduces inflammation, alleviates pain, and helps lower body temperature.

The appropriate dose of Ibu-Lysin Al is determined by the prescribing healthcare professional based on the patient’s age, weight, medical condition, and response to therapy. Dosage regimens are individualized and should follow the prescriber’s instructions without deviation.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and clinical circumstances. Generally, ibuprofen is avoided in the third trimester because of potential fetal risks, and it should only be used during pregnancy or while breastfeeding if the prescriber judges that the benefits outweigh the risks.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Ibu-Lysin Al. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Both ibuprofen and naproxen belong to the NSAID class and share similar mechanisms of COX inhibition. Ibuprofen generally has a shorter half‑life, requiring more frequent dosing, while naproxen offers a longer duration of action. Choice between them depends on clinical factors, patient tolerance, and prescriber preference.

Ibu-Lysin Al should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging to protect them from moisture, light, and excessive heat. Do not store in a refrigerator or freezer unless otherwise directed by the supplier.

Ibu-Lysin Al is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food may reduce gastrointestinal discomfort. The tablet should be swallowed whole and not chewed or crushed unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, severe renal impairment, anaphylactic reactions, and rare but severe skin reactions such as Stevens‑Johnson syndrome. Patients with a history of ulcers, kidney disease, or cardiovascular disease should be monitored closely, and any signs of serious adverse events require immediate medical attention.

Ibu-Lysin Al should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcer disease, severe renal or hepatic impairment, and in the third trimester of pregnancy. Patients on anticoagulant therapy or with uncontrolled hypertension should also discuss use with their prescriber before starting treatment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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