Product image of Ibu-Lysin Dexcel (Ibuprofen D,l-Lysinate) supplied by GNH India

Ibu-Lysin Dexcel

Active Ingredient:
Ibuprofen D,l-Lysinate
Origin:
EU

Ibu-Lysin Dexcel (Ibuprofen D,l-Lysinate)

Ibuprofen lysinate, the active ingredient in Ibu-Lysin Dexcel, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It treats mild to moderate pain, fever and inflammatory conditions in adults and children as directed by a healthcare professional.

GNH India supplies Ibu-Lysin Dexcel as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Dexcel Pharma Gmbh

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Indications & Clinical Uses

Ibu-Lysin Dexcel, an NSAID, acts on inflammatory pathways to relieve several common conditions.

  • Mild to moderate pain: reduces pain intensity and improves functional ability.
  • Fever: lowers elevated body temperature associated with infection or inflammation.
  • Inflammatory conditions: diminishes swelling and discomfort in disorders such as arthritis or musculoskeletal injuries.

How It Works

  • Ibuprofen lysinate exerts its effect by reversibly inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The resulting decrease in prostaglandin synthesis reduces inflammation, pain signaling, and fever generation at the site of tissue injury or infection.

Side Effects

Adverse reactions may occur with any NSAID therapy.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Skin rash or mild itching.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Severe allergic reactions such as anaphylaxis.
  • Renal impairment or reduced kidney function.
  • Hepatic dysfunction, including elevated liver enzymes.
  • Cardiovascular events like myocardial infarction or stroke.
  • Severe cutaneous reactions (e.g., Stevens‑Johnson syndrome).

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Assess renal function: avoid use in patients with severe renal impairment.
  • Evaluate gastrointestinal risk: use gastro‑protective agents if history of ulcer disease.
  • Use the lowest effective dose for the shortest duration needed.
  • Avoid in individuals with known hypersensitivity to ibuprofen or other NSAIDs.
  • Monitor cardiovascular status in patients with existing heart disease.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Ibuprofen lysinate can affect the activity of several other medicines.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Lithium: elevated lithium levels leading to toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in renal function.
  • Diuretics: enhanced risk of renal impairment.
  • Corticosteroids: increased gastrointestinal ulcer risk.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.
  • Methotrexate: reduced clearance and potential toxicity.

Frequently Asked Questions

Ibu-Lysin Dexcel is indicated for the relief of mild to moderate pain, reduction of fever, and management of inflammatory conditions such as arthritis or musculoskeletal injuries. It is used in adults and children when prescribed by a qualified healthcare professional.

Ibuprofen lysinate works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for prostaglandin synthesis. By lowering prostaglandin levels, it reduces inflammation, alleviates pain, and helps lower elevated body temperature.

The appropriate dose of Ibu-Lysin Dexcel is determined by the prescribing clinician based on the patient’s age, weight, medical condition, and response to therapy. Standard adult dosing ranges are outlined in clinical guidelines, but the exact regimen should always be set by a qualified prescriber.

Safety of ibuprofen lysinate in pregnancy and lactation has not been definitively established. It should only be used when the potential benefit justifies the potential risk to the fetus or infant, and only under the guidance of a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Ibuprofen lysinate is a lysine salt form of ibuprofen that offers improved aqueous solubility, which can lead to faster absorption and onset of action compared with standard ibuprofen tablets. Efficacy and safety profiles are generally comparable, though individual response may vary.

Store Ibu-Lysin Dexcel at room temperature, preferably below 25 °C. Keep the product in its original packaging to protect it from moisture and light. Do not store in extreme heat or humidity, and keep out of reach of children.

Ibu-Lysin Dexcel is taken orally with a glass of water. It may be taken with or without food, although taking it with food can help reduce gastrointestinal discomfort in some patients.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, renal impairment, hepatic dysfunction, and cardiovascular events like heart attack or stroke. Patients should be monitored for these events, especially if they have pre‑existing risk factors.

Individuals with known hypersensitivity to ibuprofen, other NSAIDs, or any component of the formulation should avoid it. It is also contraindicated in patients with active gastrointestinal ulcer disease, severe renal or hepatic impairment, and those at high risk for cardiovascular events unless specifically advised by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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