Product image of Ibu-Lysin Heumann (Ibuprofen Lysine) supplied by GNH India

Ibu-Lysin Heumann

Active Ingredient:
Ibuprofen Lysine
Origin:
EU

Ibu-Lysin Heumann (Ibuprofen Lysine)

Ibuprofen Lysine, the active ingredient in Ibu-Lysin Heumann, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an oral tablet for oral use. It provides analgesic, antipyretic and anti‑inflammatory effects for the temporary relief of mild to moderate pain and fever in adults.

GNH India supplies Ibu-Lysin Heumann as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for healthcare providers across multiple regions. Our distribution network ensures timely delivery and regulatory compliance.

Manufacturer / TM Owner

Heumann Pharma Gmbh & Co. Generica Kg

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Indications & Clinical Uses

Ibuprofen Lysine, an NSAID, reduces inflammation and pain by inhibiting cyclo‑oxygenase enzymes.

  • Headache: relief of mild to moderate tension‑type headache.
  • Dental pain: reduction of postoperative dental pain and inflammation.
  • Musculoskeletal pain: alleviation of sprains, strains and back pain.
  • Fever: reduction of elevated body temperature.
  • Osteoarthritis: improvement of joint pain and stiffness in osteoarthritis.

How It Works

  • Ibuprofen Lysine exerts its effect by non‑selectively inhibiting cyclo‑oxygenase‑1 (COX‑1) and cyclo‑oxygenase‑2 (COX‑2) enzymes, leading to decreased synthesis of prostaglandins that mediate inflammation, pain, and fever. This reduction in prostaglandin levels diminishes peripheral sensitization and central pain signaling, providing analgesic and antipyretic actions.

Side Effects

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia or heartburn.
  • Headache: mild to moderate intensity.
  • Dizziness: transient light‑headedness.
  • Rash: mild skin irritation.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Renal impairment or acute kidney injury.
  • Severe hypersensitivity reactions, including anaphylaxis.
  • Hepatic injury or elevated liver enzymes.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Cardiovascular events such as myocardial infarction or stroke.

Precautions & Warnings

Before initiating therapy, consider patient‑specific risk factors and monitor appropriately.

  • Assess gastrointestinal risk: use lowest effective dose and consider gastro‑protective agents.
  • Monitor renal function: avoid in patients with severe renal impairment.
  • Avoid in third‑trimester pregnancy: risk of fetal ductus arteriosus closure.
  • Use with food or antacids to reduce stomach irritation.
  • Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen Lysine may alter the effect of several concomitant medicines.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: heightened risk of ulceration and bleeding.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in renal function.
  • Diuretics: may enhance renal adverse effects.
  • Methotrexate: decreased clearance leading to toxicity.
  • SSRIs: potential for increased bleeding.
  • Alcohol: synergistic gastric irritation.

Frequently Asked Questions

Ibu-Lysin Heumann contains ibuprofen lysine, an NSAID indicated for the temporary relief of mild to moderate pain such as headache, dental pain, musculoskeletal discomfort, and for reducing fever. It is also used to improve symptoms of osteoarthritis and other inflammatory conditions as prescribed by a healthcare professional.

Ibuprofen lysine works by non‑selectively inhibiting the cyclo‑oxygenase enzymes COX‑1 and COX‑2, which are essential for prostaglandin production. Lower prostaglandin levels reduce inflammation, pain signaling, and fever generation, providing the therapeutic effects associated with NSAIDs.

The appropriate dose of Ibu-Lysin Heumann is determined by the prescribing clinician based on the patient’s age, weight, medical condition, and response to therapy. Healthcare providers follow established guidelines for ibuprofen lysine dosing and adjust as needed for safety and efficacy.

Ibuprofen lysine is generally avoided in the third trimester of pregnancy because of potential risks to the fetal ductus arteriosus. Use during the first and second trimesters should only occur if clearly needed and after consulting a physician. Limited data are available for breastfeeding, so a risk‑benefit assessment is required.

To request Ibu-Lysin Heumann, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will ask for trade or institutional credentials. The sales team then provides pricing, availability, shipping details (including any cold‑chain requirements) and assists with import documentation.

Ibuprofen lysine is a salt form of ibuprofen that may offer faster absorption and onset of action compared with standard ibuprofen tablets. Therapeutic efficacy and safety profiles are similar, but the lysine salt can be advantageous when rapid pain relief is desired. Choice between the two depends on clinical judgment and patient preference.

Ibu-Lysin Heumann should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and avoid storing it in bathrooms or other humid environments.

The medication is taken orally, usually with a full glass of water. It can be taken with or without food; however, taking it with meals or an antacid may reduce gastrointestinal discomfort. Patients should follow the dosing schedule prescribed by their healthcare provider.

Serious risks include gastrointestinal bleeding or ulcer perforation, especially in patients with a history of ulcers or who use anticoagulants. Renal impairment, severe hypersensitivity reactions such as anaphylaxis, and cardiovascular events like myocardial infarction or stroke are also important safety concerns that require monitoring.

Ibu-Lysin Heumann is contraindicated in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulceration, severe renal or hepatic disease, and in the third trimester of pregnancy. Caution is also advised for patients with uncontrolled hypertension, heart failure, or those taking certain anticoagulants.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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