Product image of Ibudolor Direkt Stada (Ibuprofen) supplied by GNH India

Ibudolor Direkt Stada

Active Ingredient:
Ibuprofen
Origin:
EU

Ibudolor Direkt Stada (Ibuprofen)

Ibuprofen, the active ingredient in Ibudolor Direkt Stada, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It treats mild to moderate pain, fever, and inflammatory conditions such as arthritis in adults.

GNH India supplies Ibudolor Direkt Stada as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stada D.O.O.

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Indications & Clinical Uses

Ibuprofen is an NSAID that reduces pain and inflammation by inhibiting cyclooxygenase enzymes.

  • Mild to moderate pain: provides analgesic relief for headache, dental pain, and musculoskeletal discomfort.
  • Fever: lowers elevated body temperature associated with infections or inflammatory states.
  • Inflammatory arthritis: decreases joint inflammation and swelling in osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2. This inhibition blocks the conversion of arachidonic acid to prostaglandins, which are mediators of pain, fever, and inflammation. Reduced prostaglandin synthesis leads to decreased sensitisation of nociceptors, lower hypothalamic set‑point temperature, and diminished inflammatory exudate formation.

Side Effects

Adverse reactions may range from mild gastrointestinal discomfort to rare but serious systemic events.

Common Side Effects

  • Nausea: occasional upset stomach after ingestion.
  • Dyspepsia: indigestion or heartburn.
  • Headache: mild to moderate intensity.
  • Dizziness: transient light‑headedness.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Acute renal impairment, especially in dehydrated patients.
  • Severe allergic reactions such as anaphylaxis.
  • Hepatotoxicity: elevated liver enzymes or jaundice.
  • Thrombocytopenia: reduced platelet count leading to bleeding.

Precautions & Warnings

Before using ibuprofen, consider the following safety measures.

  • Assess renal function: avoid in patients with severe renal impairment.
  • Monitor gastrointestinal risk: use with food and avoid in those with a history of ulcers.
  • Avoid in third‑trimester pregnancy: potential fetal harm.
  • Use caution with anticoagulants: increased bleeding risk.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Ibuprofen can interact with several medication classes; some require avoidance while others need monitoring.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened risk of bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): increased bleeding tendency.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: may reduce renal function.
  • Diuretics: risk of renal impairment.
  • Lithium: potential increase in serum lithium levels.

Frequently Asked Questions

Ibudolor Direkt Stada contains ibuprofen, an NSAID indicated for the relief of mild to moderate pain, reduction of fever, and management of inflammatory conditions such as osteoarthritis and rheumatoid arthritis. It is commonly prescribed for headaches, dental pain, musculoskeletal discomfort, and febrile illnesses.

Ibuprofen works by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2. This blocks the conversion of arachidonic acid into prostaglandins, which are key mediators of pain, fever, and inflammation. Lower prostaglandin levels reduce sensitisation of pain receptors, lower hypothalamic temperature set‑point, and diminish inflammatory swelling.

The appropriate dose of Ibudolor Direkt Stada is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and response to therapy. Patients should follow the prescriber’s instructions and not exceed the recommended amount without medical guidance.

Ibuprofen is generally avoided in the third trimester of pregnancy because it may affect fetal cardiovascular development. Use during the first two trimesters should only occur if the benefit outweighs the risk and under medical supervision. Limited data exist for breastfeeding; a prescriber should evaluate safety before use.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifying trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Ibuprofen is an NSAID, whereas acetaminophen (paracetamol) is an analgesic/antipyretic with minimal anti‑inflammatory activity. Ibuprofen provides stronger anti‑inflammatory effects but carries higher gastrointestinal and renal risk. Acetaminophen is gentler on the stomach but lacks the anti‑inflammatory benefit that ibuprofen offers.

Store Ibudolor Direkt Stada at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging to protect them from moisture and light. Do not store in extreme heat or humidity, and keep out of reach of children.

Ibudolor Direkt Stada is taken orally with a full glass of water. It can be taken with or without food, although ingesting it with meals may reduce gastrointestinal discomfort. Swallow the tablet whole; do not crush or chew unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulcer perforation, acute renal impairment, severe allergic reactions such as anaphylaxis, and cardiovascular events like myocardial infarction, especially with high‑dose or prolonged use. Patients should be monitored for signs of bleeding, reduced urine output, or allergic symptoms.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulceration, severe renal or hepatic impairment, and patients in the third trimester of pregnancy should avoid using Ibudolor Direkt Stada. Consultation with a healthcare provider is essential before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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