Product image of Ibufen (Ibuprofen) supplied by GNH India

Ibufen

Active Ingredient:
Ibuprofen
Origin:
EU

Ibufen (Ibuprofen)

Ibuprofen, the active ingredient in Ibufen, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It relieves pain, reduces fever, and decreases inflammation in adults and children when appropriate.

GNH India supplies Ibufen as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Zaklady Farmaceutyczne Polpharma S.A.

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Indications & Clinical Uses

  • Ibufen (ibuprofen) acts on inflammatory pathways to provide symptomatic relief in several common conditions.
  • Pain: reduces mild to moderate pain such as headache, dental or musculoskeletal discomfort.
  • Fever: lowers elevated body temperature associated with infections or inflammatory states.
  • Inflammation: diminishes swelling and stiffness in conditions like arthritis or soft‑tissue injury.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The reduction in prostaglandin synthesis leads to decreased inflammation, pain signaling, and fever generation.

Side Effects

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects

  • Gastrointestinal discomfort such as dyspepsia or heartburn.
  • Nausea or mild vomiting.
  • Headache.
  • Dizziness.
  • Mild skin rash.
  • Elevated blood pressure in some individuals.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Severe allergic reactions including anaphylaxis.
  • Renal impairment or acute kidney injury.
  • Hepatotoxicity manifested by jaundice.
  • Cardiovascular events such as myocardial infarction or stroke.
  • Blood disorders like thrombocytopenia.

Precautions & Warnings

  • Before using Ibufen, consider the following safety measures.
  • Assess renal and hepatic function: adjust use if impairment is present.
  • Avoid concurrent use with other NSAIDs or anticoagulants: increased bleeding risk.
  • Monitor for gastrointestinal symptoms: discontinue if severe ulceration occurs.
  • Use caution in patients with cardiovascular disease: risk of thrombotic events.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Ibufen can interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • Selective COX‑2 inhibitors: additive renal and cardiovascular toxicity.
  • High‑dose aspirin: increased gastrointestinal injury.
  • Certain antihypertensives (e.g., ACE inhibitors, diuretics): may reduce blood‑pressure control.
  • Lithium: possible increase in serum lithium levels.

Moderate Interactions (Monitor Closely)

  • Other NSAIDs or corticosteroids: monitor for GI complications.
  • Methotrexate: potential for increased toxicity.
  • SSRIs or SNRIs: watch for bleeding tendencies.
  • Diuretics: assess renal function regularly.
  • Cyclosporine: monitor renal parameters.

Frequently Asked Questions

Ibufen contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, lower fever, and reduce inflammation associated with conditions such as headaches, dental pain, musculoskeletal aches, and arthritis.

Ibuprofen works by non‑selectively blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are needed to produce prostaglandins. Fewer prostaglandins mean less inflammation, reduced pain signaling, and a lower fever response.

The appropriate dose of Ibufen is determined by a qualified prescriber based on the patient’s age, weight, clinical condition, and other medications. Patients should follow the healthcare professional’s instructions and not exceed the recommended amount.

Safety data for ibuprofen in pregnancy and lactation are limited. It is generally avoided in the third trimester and used only if the benefit outweighs the risk. Breastfeeding mothers should consult a healthcare provider before use.

To place an order, submit an enquiry on the Ibufen product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibufen (ibuprofen) offers a balance of analgesic, antipyretic and anti‑inflammatory effects with a relatively short half‑life, allowing flexible dosing. Compared with aspirin, it has less antiplatelet activity, and versus selective COX‑2 inhibitors, it carries a lower cardiovascular risk but a higher gastrointestinal risk.

Store Ibufen at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Ibufen is intended for oral administration. It may be taken with or without food, although taking it with a meal or a glass of milk can help reduce stomach irritation.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, kidney injury, liver toxicity, and increased risk of heart attack or stroke, especially with high‑dose or prolonged use.

Ibufen should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding, severe heart failure, uncontrolled hypertension, or advanced renal or hepatic disease unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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