Product image of Ibufen (Ibuprofen) supplied by GNH India

Ibufen

Active Ingredient:
Ibuprofen
Origin:
EU

Ibufen (Ibuprofen)

Ibuprofen, the active ingredient in Ibufen, is a nonsteroidal anti-inflammatory drug (NSAID) presented as oral tablets for oral use. It treats pain, fever, inflammation and is commonly employed in adults and children as directed by a healthcare professional.

GNH India supplies Ibufen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for global distribution. Customers benefit from reliable logistics and consistent product availability across multiple markets.

Manufacturer / TM Owner

Antibiotice Sa

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Indications & Clinical Uses

Ibufen (ibuprofen) is used to manage conditions involving pain, fever and inflammation.

  • Pain: Reduces mild to moderate pain such as headache, dental or musculoskeletal discomfort.
  • Fever: Lowers elevated body temperature associated with infectious or inflammatory processes.
  • Inflammation: Decreases swelling and stiffness in conditions like osteoarthritis and rheumatoid arthritis.
  • Arthritis: Improves joint function and alleviates chronic inflammatory joint pain.

How It Works

  • Ibuprofen inhibits both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which reduces the synthesis of prostaglandins that mediate pain, fever and inflammation. By decreasing prostaglandin levels, it diminishes peripheral sensitization of nociceptors and lowers the hypothalamic set‑point for body temperature, providing analgesic, antipyretic and anti‑inflammatory effects.

Side Effects

Ibufen may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia or abdominal discomfort.
  • Headache: mild to moderate intensity.
  • Dizziness: transient sensation of light‑headedness.
  • Rash: mild skin irritation or erythema.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration: potentially life‑threatening hemorrhage.
  • Renal impairment: reduced kidney function, especially in susceptible individuals.
  • Severe allergic reaction: anaphylaxis, angioedema or Stevens‑Johnson syndrome.

Precautions & Warnings

Before using Ibufen, consider the following safety measures.

  • Assess gastrointestinal risk: Evaluate history of ulcers or bleeding before initiating therapy.
  • Use lowest effective dose: Limit duration to the shortest period needed for symptom control.
  • Monitor renal function: Check kidney parameters in patients with pre‑existing renal impairment.
  • Avoid use in third trimester: Contraindicated during late pregnancy due to fetal risks.
  • Take with food or milk: Reduces risk of stomach irritation.
  • Store below 25°C: Keep in the original packaging, protect from moisture and heat.

Avoid Interactions

Ibufen can interact with several medicines; some combinations should be avoided while others require monitoring.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): Increases risk of serious bleeding.
  • Lithium: May raise lithium serum levels and toxicity.
  • Methotrexate: Enhances methotrexate toxicity, especially at high doses.

Moderate Interactions (Monitor Closely)

  • Selective serotonin reuptake inhibitors (SSRIs): May modestly increase bleeding risk.
  • ACE inhibitors or diuretics: Can reduce renal perfusion, requiring monitoring of kidney function.

Frequently Asked Questions

Ibufen contains ibuprofen, which is indicated for the relief of mild to moderate pain, reduction of fever, and mitigation of inflammation. It is commonly prescribed for headaches, dental pain, musculoskeletal aches, arthritic conditions, and febrile illnesses when a non‑opioid analgesic is appropriate.

Ibuprofen works by blocking the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for the production of prostaglandins. Prostaglandins amplify pain signals, raise body temperature, and promote inflammation, so their reduction leads to analgesic, antipyretic, and anti‑inflammatory effects.

The appropriate dose of Ibufen is determined by a qualified prescriber based on the patient’s age, weight, clinical condition, and response to therapy. Healthcare professionals tailor the regimen to achieve effective symptom control while minimizing potential risks.

Safety data for ibuprofen in pregnancy and lactation are limited. It is generally avoided in the third trimester because of potential fetal complications, and caution is advised throughout pregnancy and while breastfeeding. Patients should discuss individual risks with their obstetrician or physician.

To order Ibufen, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Ibufen (ibuprofen) shares the core NSAID mechanism of COX inhibition with drugs such as naproxen and diclofenac. Compared with some NSAIDs, ibuprofen has a relatively short half‑life, allowing flexible dosing, and it is often preferred for short‑term pain or fever. Individual tolerability and specific risk profiles guide the choice among NSAIDs.

Ibufen should be stored at temperatures below 25 °C. Keep the tablets in their original container, protect them from moisture, direct sunlight and excessive heat. Proper storage maintains product stability and potency throughout its shelf life.

Ibufen is administered orally. Tablets are swallowed whole with a full glass of water, preferably with food or milk to lessen gastrointestinal irritation. The exact administration schedule is set by the prescribing clinician.

Serious adverse events include gastrointestinal bleeding or ulceration, severe renal impairment, and hypersensitivity reactions such as anaphylaxis or Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they notice black stools, sudden kidney problems, swelling, rash, or difficulty breathing.

Ibufen is contraindicated in individuals with a known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, patients in the third trimester of pregnancy, and persons with severe renal or hepatic impairment unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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