Product image of Ibuflam (Ibuprofen) supplied by GNH India

Ibuflam

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuflam (Ibuprofen)

Ibuprofen, the active ingredient in Ibuflam, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It is employed to relieve pain, reduce fever, and diminish inflammation in adults and children when appropriate.

GNH India supplies Ibuflam as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for global healthcare providers, with a distribution network that ensures timely delivery and regulatory compliance across multiple regions.

Manufacturer / TM Owner

Aenova Ip Gmbh

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Indications & Clinical Uses

Ibuflam (ibuprofen) is indicated for conditions involving pain, fever and inflammation.

  • Pain: provides relief from mild to moderate acute or chronic pain such as headache, dental or musculoskeletal discomfort.
  • Fever: lowers elevated body temperature associated with infections or inflammatory processes.
  • Inflammation: reduces swelling and redness in conditions like sprains, strains or minor injuries.
  • Arthritis: helps alleviate joint pain and stiffness in osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen exerts its therapeutic effect by reversibly inhibiting both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes. This inhibition decreases the synthesis of prostaglandins, which are mediators responsible for pain sensation, fever generation, and inflammation. By lowering prostaglandin levels, ibuprofen diminishes the physiological responses that underlie these symptoms.

Side Effects

Ibuflam may cause a range of adverse reactions, which are generally classified by frequency and severity.

Common Side Effects

  • Stomach upset or dyspepsia
  • Nausea or vomiting
  • Headache
  • Dizziness
  • Mild rash or itching
  • Heartburn

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration
  • Severe allergic reactions (anaphylaxis, angioedema)
  • Acute kidney injury or reduced renal function
  • Elevated liver enzymes or hepatitis
  • Cardiovascular events such as myocardial infarction or stroke

Precautions & Warnings

Before using Ibuflam, consider the following safety measures.

  • Assess gastrointestinal risk: avoid in patients with active ulcers or a history of GI bleeding.
  • Evaluate renal function: use caution in individuals with impaired kidney function or dehydration.
  • Review cardiovascular history: limit use in patients with established heart disease or high thrombotic risk.
  • Avoid in late pregnancy: do not use during the third trimester unless specifically directed by a physician.
  • Use the lowest effective dose for the shortest duration needed.
  • Store at ambient temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Ibuflam can interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: heightened gastrointestinal toxicity.
  • Corticosteroids: additive risk of ulceration and bleeding.
  • Lithium: ibuprofen may raise lithium serum concentrations.
  • Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely):\n- ACE inhibitors or ARBs: possible reduction in renal function.

  • Diuretics: may enhance nephrotoxic potential.
  • Selective serotonin reuptake inhibitors (SSRIs): increased bleeding tendency.
  • Beta‑blockers: potential attenuation of antihypertensive effect.
  • Antihypertensive agents: monitor blood pressure for changes.

Frequently Asked Questions

Ibuflam contains ibuprofen, an NSAID that is used to relieve mild to moderate pain, lower fever, and reduce inflammation caused by conditions such as headaches, dental pain, musculoskeletal injuries, and arthritis. It is prescribed when a non‑opioid analgesic and antipyretic are appropriate.

Ibuprofen works by blocking the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for producing prostaglandins. Prostaglandins mediate pain, fever, and inflammation, so their reduction leads to symptom relief.

The exact dose of Ibuflam is determined by the prescribing healthcare professional based on the patient’s age, weight, condition being treated, and overall health status. Patients should follow the prescriber’s instructions and never exceed the recommended amount.

Ibuprofen is generally avoided in the third trimester of pregnancy because of potential risks to the fetus. During the first and second trimesters, it may be used only if the benefit outweighs the risk and under medical supervision. Limited data are available for breastfeeding, so a healthcare provider should be consulted before use.

To place an order, submit an enquiry on the Ibuflam product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and required import documentation.

Ibuflam (ibuprofen) offers a balanced profile of analgesic, antipyretic and anti‑inflammatory activity with a relatively short half‑life, allowing flexible dosing. Compared with naproxen, ibuprofen has a quicker onset but may require more frequent dosing. Compared with aspirin, ibuprofen provides similar pain relief with a lower risk of gastric irritation at standard doses.

Ibuflam should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture, heat and direct sunlight, and ensure the packaging is tightly closed to maintain product stability.

Ibuflam is taken orally with a full glass of water. It can be taken with or without food; however, taking it with food or milk may lessen stomach discomfort. Swallow the tablet whole; do not crush or chew unless specifically instructed by a healthcare professional.

The most serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, acute kidney injury, and increased cardiovascular events like heart attack or stroke, especially with high‑dose or prolonged use. Patients should seek immediate medical attention if they notice signs of serious bleeding, rash, swelling, or chest pain.

Ibuflam should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, or advanced kidney disease. It is also contraindicated in the third trimester of pregnancy and should be used with caution in patients taking anticoagulants, other NSAIDs, or certain antihypertensive drugs.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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