Product image of Ibugard (Ibuprofen) supplied by GNH India

Ibugard

Active Ingredient:
Ibuprofen
Origin:
EU

Ibugard (Ibuprofen)

Ibuprofen, the active ingredient in Ibugard, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It treats mild to moderate pain, reduces fever, and alleviates inflammation in conditions such as arthritis.

GNH India supplies Ibugard as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Zaklady Farmaceutyczne Polpharma S.A.

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Indications & Clinical Uses

Ibuprofen acts on the cyclooxygenase pathway to provide analgesic, antipyretic, and anti‑inflammatory effects.

  • Pain (mild to moderate): Relieves headache, dental, musculoskeletal and menstrual discomfort.
  • Fever: Lowers elevated body temperature associated with infections or inflammatory states.
  • Arthritis: Reduces joint inflammation and pain in osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen non‑selectively inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The resulting decrease in prostaglandin synthesis reduces peripheral sensitization of nociceptors, lowers the hypothalamic set‑point for temperature, and diminishes inflammatory vascular responses.

Side Effects

Common side effects of ibuprofen are generally mild and reversible.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort.
  • Headache: transient mild to moderate headache.
  • Dizziness: occasional light‑headedness.
  • Rash: mild skin erythema or itching.
  • Diarrhea: loose stools without blood.
  • Elevated liver enzymes: mild, asymptomatic increase.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Renal impairment or acute kidney injury.
  • Severe allergic reactions such as anaphylaxis.
  • Hepatotoxicity with marked liver enzyme elevation.
  • Cardiovascular thrombotic events (myocardial infarction, stroke).
  • Blood dyscrasias: thrombocytopenia or leukopenia.

Precautions & Warnings

Before using Ibugard, consider the following safety measures.

  • Assess renal function: Use caution in patients with kidney disease.
  • Evaluate gastrointestinal risk: Avoid in history of ulcers or bleeding.
  • Monitor cardiovascular status: Use carefully in patients with heart disease.
  • Consider pregnancy: Discuss risks with healthcare provider.
  • Review concomitant NSAIDs: Avoid combined use to reduce toxicity.
  • Store at ambient temperature: Keep below 25°C, in original packaging, protect from moisture.

Avoid Interactions

Ibuprofen can interact with several drug classes; awareness helps prevent adverse events.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): Increases bleeding risk.
  • Other NSAIDs or aspirin: Heightens gastrointestinal toxicity.
  • Corticosteroids: Potentiates ulcer risk.
  • Selective serotonin reuptake inhibitors (SSRIs): Elevates bleeding potential.
  • ACE inhibitors or diuretics: May reduce renal function.

Moderate Interactions (Monitor Closely)

  • Lithium: Ibuprofen can raise lithium levels.
  • Methotrexate: May increase toxicity.
  • Cyclosporine: Potential for increased nephrotoxicity.
  • Blood pressure medications: May blunt antihypertensive effect.
  • Diabetic agents: May affect glucose control.

Frequently Asked Questions

Ibugard contains ibuprofen, an NSAID used to relieve mild to moderate pain, reduce fever, and treat inflammatory conditions such as osteoarthritis and rheumatoid arthritis. It is commonly prescribed when a non‑opioid analgesic is appropriate.

Ibuprofen non‑selectively inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, decreasing the synthesis of prostaglandins that mediate pain, fever and inflammation. By lowering prostaglandin levels, it diminishes the sensitization of nerve endings and reduces vascular dilation.

The specific dose of Ibugard is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition and response. Dosage instructions are provided on the prescription label and should be followed exactly as directed.

Safety of ibuprofen in pregnancy and lactation is classified as uncertain; it is generally avoided in the third trimester and used only if the benefit outweighs risk. Breastfeeding mothers should consult a physician, as ibuprofen passes into milk in small amounts.

To place an order, submit an enquiry on the Ibugard product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Ibugard (ibuprofen) offers a well‑established balance of analgesic, antipyretic and anti‑inflammatory activity with a relatively short half‑life, allowing flexible dosing. Compared with naproxen, it has a quicker onset but may require more frequent dosing; versus acetaminophen, it provides anti‑inflammatory effects not seen with acetaminophen.

Ibugard should be stored at ambient temperature, below 25 °C, in the original container to protect it from moisture and light. Keep the product out of reach of children and do not use after the expiration date.

Ibugard is taken orally, usually with a glass of water. It may be taken with or without food; taking it with food can lessen gastrointestinal discomfort. Swallow tablets whole; do not crush or chew unless instructed by a healthcare professional.

The most serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, renal impairment, and increased risk of cardiovascular events like heart attack or stroke, especially with high‑dose or prolonged use.

Ibugard should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcer or bleeding, severe heart failure, uncontrolled hypertension, and in patients receiving anticoagulant therapy unless closely monitored by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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