Product image of Ibugard (Ibuprofen) supplied by GNH India

Ibugard

Active Ingredient:
Ibuprofen
Origin:
EU

Ibugard (Ibuprofen)

Ibuprofen, the active ingredient in Ibugard, is a nonsteroidal anti‑inflammatory drug (NSAID) presented as a suppository for rectal use. It provides analgesic, antipyretic and anti‑inflammatory effects for the temporary relief of mild to moderate pain, fever and inflammation in adults and children when appropriate.

GNH India supplies Ibugard as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product conforms to European Union quality standards and is manufactured under GMP conditions, ensuring consistent potency and safety for patients across diverse healthcare settings.

Manufacturer / TM Owner

Zaklady Farmaceutyczne Polpharma S.A.

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Indications & Clinical Uses

Ibuprofen, an NSAID, reduces pain, fever and inflammation by inhibiting cyclooxygenase enzymes.

  • Pain: provides relief of mild to moderate acute pain.
  • Fever: lowers elevated body temperature.
  • Inflammation: diminishes swelling associated with musculoskeletal conditions.
  • Post‑operative discomfort: helps manage discomfort after minor surgical procedures.

How It Works

  • Ibuprofen reversibly inhibits both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. This reduction in prostaglandin synthesis leads to lowered inflammation, pain signaling, and fever generation at sites of tissue injury.

Side Effects

Common Side Effects

  • Rectal irritation: mild burning or discomfort at the application site.
  • Nausea: occasional feeling of queasiness.
  • Headache: transient head pain.
  • Dizziness: light‑headed sensation.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: signs include black stools or vomiting blood.
  • Ulcer perforation: severe abdominal pain requiring urgent care.
  • Severe allergic reaction: rash, swelling, or difficulty breathing (anaphylaxis).
  • Renal impairment: reduced urine output or swelling indicating kidney issues.

Precautions & Warnings

Before using Ibugard, consider the following precautions:

  • Assess renal function: avoid in patients with severe renal impairment.
  • Evaluate gastrointestinal risk: use with caution in individuals with a history of ulcers or bleeding.
  • Monitor cardiovascular status: NSAIDs may increase the risk of thrombotic events.
  • Use in pregnancy: safety not established; avoid in the third trimester.
  • Avoid concomitant anticoagulants: increased bleeding risk.
  • Store at room temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Ibuprofen may interact with several medicines. Review the following categories:

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin, DOACs): increased risk of bleeding.
  • ACE inhibitors or ARBs: may reduce renal function when combined.
  • Lithium: ibuprofen can raise lithium serum levels, risking toxicity.

Moderate Interactions (Monitor Closely)

  • Diuretics (loop or thiazide): may affect renal clearance of ibuprofen.
  • Methotrexate: reduced excretion can lead to toxicity.
  • SSRIs: additive effect on bleeding risk.

Frequently Asked Questions

Ibugard is a rectal suppository containing ibuprofen, an NSAID that provides temporary relief of mild to moderate pain, reduces fever, and lessens inflammation associated with conditions such as musculoskeletal aches, headaches, and febrile illnesses.

Ibuprofen in Ibugard reversibly blocks the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for prostaglandin production. By lowering prostaglandin levels, it diminishes the signals that cause pain, fever, and inflammatory swelling.

The appropriate dose of Ibugard is determined by a qualified healthcare professional based on the patient’s age, weight, clinical condition, and response to therapy. The prescriber will specify the exact amount and frequency.

Safety of ibuprofen suppositories in pregnancy has not been established, and use is generally avoided, especially in the third trimester. Breastfeeding mothers should consult a physician, as ibuprofen can be excreted in breast milk.

To order Ibugard, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Ibugard offers the same active ingredient as oral ibuprofen tablets but in a rectal suppository form, which can be advantageous for patients who cannot swallow tablets or need rapid systemic absorption. Efficacy is comparable, while the route may affect onset time and gastrointestinal tolerance.

Store Ibugard at room temperature, below 25 °C, in its original packaging. Keep it away from moisture, direct sunlight, and excessive heat to maintain stability and potency.

Ibugard is inserted rectally, preferably after a bowel movement, with the suppository placed gently into the rectum using a clean finger. The patient should remain lying down for a few minutes to ensure proper absorption.

Serious risks include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis, and renal impairment, especially in patients with pre‑existing kidney disease or who take other nephrotoxic drugs.

Ibugard should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding, severe renal or hepatic impairment, and pregnant women in the third trimester unless directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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