Product image of Ibuhexal Plus Paracetamol (Ibuprofen, Paracetamol) supplied by GNH India

Ibuhexal Plus Paracetamol

Active Ingredient:
Ibuprofen, Paracetamol
Origin:
EU

Ibuhexal Plus Paracetamol (Ibuprofen, Paracetamol)

Ibuprofen and Paracetamol, the active ingredient in Ibuhexal Plus Paracetamol, is a NSAID/Analgesic presented as a combination tablet for oral use. It provides relief of mild to moderate pain, reduces fever, and lessens inflammation in adults and children when appropriate.

GNH India supplies Ibuhexal Plus Paracetamol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory compliance. The company leverages robust supply chain capabilities to meet global demand.

Manufacturer / TM Owner

Hexal Ag

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Indications & Clinical Uses

  • Ibuhexal Plus Paracetamol combines ibuprofen and paracetamol to address pain, fever and inflammation across common clinical conditions.
  • Mild to moderate pain: reduces discomfort from headaches, dental procedures, musculoskeletal aches, and menstrual cramps.
  • Fever: lowers elevated body temperature associated with viral or bacterial infections.
  • Inflammation: alleviates swelling and redness in conditions such as arthritis or soft‑tissue injuries.

How It Works

  • Ibuprofen inhibits cyclo‑oxygenase‑1 and cyclo‑oxygenase‑2 enzymes, decreasing peripheral prostaglandin synthesis and thereby producing anti‑inflammatory, analgesic and antipyretic effects. Paracetamol acts centrally by inhibiting COX activity within the brain and modulating the endocannabinoid system, leading to analgesia and fever reduction. The combined action provides complementary pain relief and temperature control, allowing synergistic benefit while limiting individual dose requirements.

Side Effects

Like all NSAID/analgesic combinations, Ibuhexal Plus Paracetamol may cause adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Nausea: mild stomach upset or queasiness.
  • Headache: transient head discomfort.
  • Dizziness: feeling light‑headed or unsteady.
  • Rash: mild skin redness or itching.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction with breathing difficulty.
  • Liver injury: elevated enzymes or hepatitis.
  • Gastrointestinal bleeding: blood in stool or vomiting blood.
  • Renal impairment: reduced kidney function or swelling.

Precautions & Warnings

Before using Ibuhexal Plus Paracetamol, consider the following precautions to minimize risk.

  • Assess renal function: avoid in patients with severe kidney impairment.
  • Check for hypersensitivity: do not use if allergic to ibuprofen, paracetamol, or other NSAIDs.
  • Monitor hepatic health: use cautiously in liver disease.
  • Use lower doses in the elderly: increased susceptibility to gastrointestinal adverse events.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Ibuhexal Plus Paracetamol can interact with other medicines; awareness of major and moderate interactions helps ensure safe use.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or COX‑2 inhibitors: heightened gastrointestinal toxicity.
  • Concurrent high‑dose paracetamol products: potential hepatotoxicity.

Moderate Interactions (Monitor Closely)

  • Lithium therapy: ibuprofen may raise lithium serum levels.
  • Methotrexate: ibuprofen can reduce renal clearance, increasing toxicity risk.

Frequently Asked Questions

Ibuhexal Plus Paracetamol is indicated for the relief of mild to moderate pain, reduction of fever, and mitigation of inflammation. It is commonly used for headaches, dental pain, musculoskeletal aches, menstrual cramps, febrile illnesses, and inflammatory conditions such as arthritis.

Ibuprofen blocks peripheral cyclo‑oxygenase enzymes, lowering prostaglandin production and reducing inflammation, pain, and fever. Paracetamol acts mainly in the central nervous system, inhibiting COX activity and influencing the endocannabinoid system to provide analgesic and antipyretic effects. Their complementary actions produce enhanced symptom control.

The appropriate dose is set by a qualified prescriber based on the patient’s age, weight, clinical condition, and any relevant medical history. Dosage recommendations follow local regulatory guidelines and should not be altered without professional advice.

Safety data for combined ibuprofen and paracetamol use in pregnancy and lactation are limited. Healthcare professionals should evaluate the risk‑benefit profile for each individual, and pregnant or nursing women should only use the product if advised by their clinician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

The combination adds paracetamol’s central analgesic and antipyretic actions to ibuprofen’s peripheral anti‑inflammatory effects. This can provide broader symptom relief at lower individual doses, potentially reducing the risk of side effects associated with higher doses of a single agent.

Store the product at room temperature, preferably below 25 °C. Keep it in the original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Ibuhexal Plus Paracetamol is taken orally with a full glass of water. It may be taken with or without food, but if gastrointestinal upset occurs, it is advisable to take it with meals. Follow the prescriber’s instructions regarding timing and frequency.

Serious risks include severe allergic reactions such as anaphylaxis, liver injury from excessive paracetamol exposure, gastrointestinal bleeding, and acute kidney injury. Patients should seek immediate medical attention if they experience symptoms like difficulty breathing, jaundice, vomiting blood, or sudden swelling.

Individuals with known hypersensitivity to ibuprofen, paracetamol, or any NSAID component should avoid the product. It is also contraindicated in patients with severe renal or hepatic impairment, active gastrointestinal ulceration, or those taking anticoagulants without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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