Product image of Ibumax (Ibuprofen) supplied by GNH India

Ibumax

Active Ingredient:
Ibuprofen
Origin:
EU

Ibumax (Ibuprofen)

Ibuprofen, the active ingredient in Ibumax, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It is used to relieve mild to moderate pain, reduce fever, and manage inflammatory conditions such as arthritis.

GNH India supplies Ibumax as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality, regulatory compliance, and reliable supply chain management across global markets.

Manufacturer / TM Owner

Vitabalans Oy

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Indications & Clinical Uses

  • Ibuprofen, an NSAID, works by reducing inflammation and pain in various musculoskeletal and febrile conditions.
  • Mild to moderate pain: provides analgesic relief for headaches, dental pain, menstrual cramps, and musculoskeletal aches.
  • Fever: lowers elevated body temperature associated with infections or inflammatory processes.
  • Inflammatory conditions such as arthritis: decreases joint swelling and improves mobility in osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen exerts its effect by reversibly inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are key in the conversion of arachidonic acid to prostaglandins. By decreasing prostaglandin synthesis, it reduces inflammation, pain signaling, and fever generation at the site of tissue injury. The inhibition is dose‑dependent and non‑selective, affecting both constitutive and inducible COX isoforms throughout the body.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to severe, depending on individual susceptibility and dosage.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo: transient sensation of light‑headedness.
  • Skin reactions: rash or mild itching.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding: serious stomach or intestinal bleeding.
  • Renal impairment: reduced kidney function or acute kidney injury.
  • Severe hypersensitivity: anaphylaxis, angioedema, or Stevens‑Johnson syndrome.

Precautions & Warnings

When prescribing ibuprofen, several safety considerations should be evaluated to minimize risk.

  • Assess renal function: avoid use in patients with severe kidney disease or dehydration.
  • Evaluate gastrointestinal risk: use with caution in individuals with a history of ulcers or bleeding.
  • Monitor cardiovascular status: limit use in patients with uncontrolled hypertension or heart failure.
  • Review concomitant medications: avoid concurrent use with other NSAIDs, anticoagulants, or corticosteroids without supervision.
  • Pregnancy and lactation: contraindicated in the third trimester and used only if benefits outweigh risks during early pregnancy.
  • Store at ambient temperature: keep below 25 °C in the original packaging, protected from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medicines, altering its efficacy or increasing the risk of adverse events.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Selective COX‑2 inhibitors: additive gastrointestinal toxicity.
  • High‑dose aspirin: enhanced renal impairment.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce antihypertensive effect and impair renal function.
  • Diuretics: potential for reduced kidney perfusion.
  • Lithium: increased lithium serum levels.
  • Methotrexate: decreased clearance leading to toxicity.

Frequently Asked Questions

Ibumax contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain such as headaches, dental pain, menstrual cramps, and musculoskeletal aches. It also reduces fever and helps manage inflammatory conditions like osteoarthritis and rheumatoid arthritis by decreasing swelling and improving joint function.

Ibuprofen works by reversibly blocking the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for converting arachidonic acid into prostaglandins. Prostaglandins mediate pain, fever, and inflammation, so their reduced production leads to analgesic, antipyretic, and anti‑inflammatory effects throughout the body.

The appropriate dose of Ibumax is determined by a qualified prescriber based on the individual’s age, weight, medical condition, and response to therapy. Healthcare professionals follow local guidelines and consider any concomitant medications before establishing the specific dosing regimen.

Ibuprofen is generally avoided in the third trimester of pregnancy because it may affect fetal cardiovascular development. Use during the first two trimesters should only occur if the prescriber judges that the benefits outweigh the risks. Limited data are available for breastfeeding, so a healthcare professional should be consulted before use.

To order Ibumax, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Ibumax (ibuprofen) belongs to the NSAID class and is often compared with naproxen or diclofenac. Compared with naproxen, ibuprofen has a shorter half‑life, which may allow more flexible dosing but may require more frequent administration for sustained pain control. All NSAIDs share similar gastrointestinal and cardiovascular risk profiles, so choice depends on patient tolerance and clinical judgment.

Ibumax should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in their original container, protect them from moisture, direct sunlight, and excessive heat. Do not store in bathrooms or near kitchen stoves, and keep out of reach of children.

Ibumax is taken orally, usually with a full glass of water. It can be taken with or without food; however, taking it with food or milk may reduce gastrointestinal irritation. Swallow the tablet whole; do not crush, chew, or split unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, especially in patients with a history of ulcers or who use anticoagulants. Renal impairment can occur, particularly in dehydrated individuals or those with pre‑existing kidney disease. Severe hypersensitivity reactions such as anaphylaxis, angioedema, or Stevens‑Johnson syndrome require immediate medical attention.

Ibumax should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding, severe heart failure, or advanced chronic kidney disease. It is also contraindicated in the third trimester of pregnancy. Patients with uncontrolled hypertension or a history of cardiovascular events should use it only under close medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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