Product image of Ibumetin (Ibuprofen) supplied by GNH India

Ibumetin

Active Ingredient:
Ibuprofen
Origin:
EU

Ibumetin (Ibuprofen)

Ibuprofen, the active ingredient in Ibumetin, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for systemic use. It is used to relieve pain, reduce fever, and diminish inflammation in adults and children when appropriate.

GNH India supplies Ibumetin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Orifarm Healthcare A/S

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Indications & Clinical Uses

Ibumetin (ibuprofen) acts on the cyclooxygenase pathway to manage common inflammatory conditions.

  • Pain: provides analgesic relief for mild to moderate musculoskeletal and dental pain.
  • Fever: lowers elevated body temperature associated with infections or inflammatory states.
  • Inflammation: reduces swelling and discomfort in conditions such as arthritis or soft‑tissue injuries.

How It Works

  • Ibuprofen reversibly inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. Lower prostaglandin levels diminish peripheral sensitization, fever generation, and inflammatory exudate formation, resulting in analgesic, antipyretic, and anti‑inflammatory effects.

Side Effects

Adverse reactions may occur with ibuprofen use and vary in frequency and severity.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or mild abdominal pain.
  • Headache: transient tension‑type headache.
  • Dizziness: occasional light‑headedness.
  • Skin reactions: mild rash or itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: ulceration or hemorrhage requiring medical attention.
  • Renal impairment: reduced kidney function, especially with prolonged use.
  • Hypersensitivity reactions: anaphylaxis, Stevens‑Johnson syndrome, or severe skin eruptions.

Precautions & Warnings

Before using ibuprofen, consider the following safety measures.

  • Cardiovascular risk: avoid prolonged high‑dose use in patients with heart disease.
  • Renal function: monitor kidney status in individuals with pre‑existing renal impairment.
  • Gastrointestinal history: use cautiously in patients with ulcer disease or bleeding disorders.
  • Concomitant medications: review all current drugs for potential interactions.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at ambient temperature: keep below 25 °C, in the original packaging, protected from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can affect the activity of several other medicines; interactions range from moderate to major.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • High‑dose aspirin: heightened gastrointestinal toxicity.
  • Selective COX‑2 inhibitors: additive renal and cardiovascular adverse effects.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in antihypertensive efficacy.
  • Diuretics: may diminish diuretic response and affect renal function.

Frequently Asked Questions

Ibumetin contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, lower fever, and reduce inflammation associated with conditions such as arthritis, dental pain, and musculoskeletal injuries.

Ibuprofen blocks the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the production of prostaglandins—chemicals that promote pain, fever, and inflammation—thereby providing analgesic, antipyretic, and anti‑inflammatory effects.

The appropriate dose of Ibumetin is determined by the prescribing healthcare professional based on the patient’s age, weight, condition being treated, and local regulatory guidelines. Patients should follow the prescriber’s instructions exactly.

Safety of ibuprofen in pregnancy and lactation depends on the trimester and individual risk factors. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss use with their healthcare provider before taking Ibumetin.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Ibumetin (ibuprofen) offers a balanced profile of analgesic, antipyretic, and anti‑inflammatory activity with a relatively short half‑life, making it suitable for intermittent dosing. Compared with stronger NSAIDs like diclofenac, ibuprofen generally has a lower risk of cardiovascular events but may require more frequent dosing for sustained relief.

Store Ibumetin at ambient temperature, preferably below 25 °C. Keep the product in its original container, protect it from moisture, heat, and direct sunlight to maintain stability and potency.

Ibumetin is taken orally, usually with a full glass of water. It can be taken with or without food; however, taking it with food may reduce gastrointestinal discomfort.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, and renal impairment, especially with high‑dose or prolonged use. Patients should seek immediate medical attention if they notice signs of bleeding, rash, or sudden kidney problems.

Individuals with a known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, or advanced kidney disease should avoid Ibumetin unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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