Product image of Ibumetin (Ibuprofen) supplied by GNH India

Ibumetin

Active Ingredient:
Ibuprofen
Origin:
EU

Ibumetin (Ibuprofen)

Ibuprofen, the active ingredient in Ibumetin, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It treats mild to moderate pain, fever, and inflammatory conditions such as arthritis in adults and children when appropriate.
GNH India supplies Ibumetin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Orifarm Healthcare A/S

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Indications & Clinical Uses

  • Ibumetin (ibuprofen) acts on the cyclo‑oxygenase pathway to relieve pain and inflammation in several common conditions.
  • Mild to moderate pain: provides analgesic relief for headaches, dental pain, musculoskeletal aches, and postoperative discomfort.
  • Fever: lowers elevated body temperature by reducing prostaglandin‑mediated thermoregulation.
  • Arthritis and other inflammatory disorders: decreases joint swelling and pain, improving mobility in conditions such as osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes. This inhibition reduces the conversion of arachidonic acid to prostaglandins, thereby decreasing inflammation, pain signaling, and fever generation at the site of tissue injury or infection.

Side Effects

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects

  • Gastrointestinal discomfort such as nausea, dyspepsia, or heartburn.
  • Mild headache or dizziness.
  • Transient elevation of liver enzymes.
  • Skin rash or mild itching.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding, potentially leading to perforation.
  • Severe hypersensitivity reactions including anaphylaxis or Stevens‑Johnson syndrome.
  • Renal impairment manifested by reduced urine output or increased creatinine.
  • Cardiovascular events such as myocardial infarction or stroke, especially with high‑dose or prolonged use.

Precautions & Warnings

  • Before initiating ibuprofen therapy, consider the following safety measures.
  • Assess gastrointestinal risk: evaluate history of ulcers, bleeding, or chronic NSAID use.
  • Monitor renal function: avoid in patients with severe kidney disease or dehydration.
  • Check cardiovascular status: use cautiously in individuals with hypertension or heart disease.
  • Avoid concomitant use with other NSAIDs or anticoagulants unless medically justified.
  • Pregnancy and lactation: discuss risks with a healthcare professional before use.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, and protect from moisture.

Avoid Interactions

Ibuprofen can interact with several drug classes, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • High‑dose aspirin: heightened gastrointestinal toxicity.
  • Selective COX‑2 inhibitors: additive renal and cardiovascular adverse effects.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in antihypertensive effect and renal function.
  • Diuretics: may enhance renal impairment.
  • Lithium: ibuprofen can raise serum lithium levels, requiring monitoring.

Frequently Asked Questions

Ibumetin contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, reduce fever, and lessen inflammation in conditions such as arthritis, dental pain, and musculoskeletal aches. It works by decreasing prostaglandin production, which mediates pain and swelling.

Ibuprofen blocks the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin levels, ibuprofen reduces inflammation, alleviates pain signals, and helps lower elevated body temperature.

The appropriate dose of Ibumetin is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and response to therapy. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and individual risk factors. It is generally avoided in the third trimester and should only be used in pregnancy or while breastfeeding when clearly needed and after consulting a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Ibumetin (ibuprofen) offers a balance of analgesic, antipyretic, and anti‑inflammatory effects similar to other NSAIDs like naproxen or diclofenac. Compared with some alternatives, ibuprofen has a relatively short half‑life, which may require more frequent dosing but often results in a lower risk of certain gastrointestinal complications when used at standard doses.

Ibumetin should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in their original container, protect them from moisture and direct sunlight, and ensure the packaging remains tightly closed to maintain product stability.

Ibumetin is taken orally, usually with a full glass of water. It can be taken with or without food; however, taking it with food or milk may reduce the likelihood of stomach irritation. The exact administration schedule should follow the prescriber’s directions.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, kidney injury, and increased cardiovascular events like heart attack or stroke, especially with high doses or prolonged use. Patients should seek immediate medical attention if they experience symptoms such as severe abdominal pain, vomiting blood, or sudden shortness of breath.

Ibumetin should be avoided by individuals with a known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, or advanced kidney disease. It is also contraindicated in the third trimester of pregnancy and should be used with caution in patients on anticoagulants or certain antihypertensive medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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