Product image of Ibuned (Ibuprofen) supplied by GNH India

Ibuned

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuned (Ibuprofen)

Ibuprofen, the active ingredient in Ibuned, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It is employed to relieve mild to moderate pain, reduce fever, and diminish inflammation in adults and children when appropriate.

GNH India supplies Ibuned as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide, providing reliable sourcing, regulatory support, and consistent quality for global healthcare markets, with a focus on timely delivery, compliance with EU standards, and partnership with procurement teams across continents.

Manufacturer / TM Owner

Azinpharma S.R.O.

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Indications & Clinical Uses

Ibuprofen, an NSAID that reduces prostaglandin‑mediated inflammation, is indicated for the following conditions:

  • Mild to moderate pain: provides analgesic relief for headaches, dental pain, musculoskeletal aches, and menstrual discomfort.
  • Fever: lowers elevated body temperature associated with infections or inflammatory processes.
  • Inflammation: decreases swelling and redness in conditions such as arthritis, sprains, and minor injuries.

How It Works

  • Ibuprofen exerts its therapeutic effects by reversibly inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2. This inhibition blocks the conversion of arachidonic acid to prostaglandins, which are mediators of pain, fever, and inflammation. By lowering prostaglandin synthesis, ibuprofen reduces nociceptive signaling, lowers hypothalamic temperature set‑point, and diminishes vascular permeability and leukocyte infiltration at sites of tissue injury.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or heartburn.
  • Headache or dizziness.
  • Skin rash or itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Renal impairment or acute kidney injury.
  • Severe hypersensitivity reactions, including anaphylaxis.

Precautions & Warnings

When using ibuprofen, several precautions should be observed to minimize risk.

  • Assess renal function: monitor in patients with existing kidney disease.
  • Avoid in active peptic ulcer disease: increased risk of gastrointestinal bleeding.
  • Use cautiously with anticoagulants: may enhance bleeding tendency.
  • Limit use during pregnancy, especially the third trimester: potential fetal risks.
  • Discontinue if hypersensitivity to ibuprofen or other NSAIDs is known.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Ibuprofen can interact with several medicines; awareness of major and moderate interactions helps ensure safe use.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin, DOACs): increased risk of bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding potential.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal function when combined.
  • Methotrexate: ibuprofen can decrease its clearance, raising toxicity risk.

Frequently Asked Questions

Ibuned contains ibuprofen, an NSAID indicated for relief of mild to moderate pain, reduction of fever, and control of inflammation. It is commonly used for headaches, dental pain, musculoskeletal aches, menstrual discomfort, and inflammatory conditions such as arthritis or minor injuries.

Ibuprofen works by reversibly inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2. This reduces the synthesis of prostaglandins, which are chemicals that promote pain, fever, and inflammation, thereby providing analgesic, antipyretic, and anti‑inflammatory effects.

The exact dose of Ibuned is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and response to therapy. Typical adult regimens range from 200 mg to 400 mg every 4‑6 hours, not to exceed the maximum daily limit, but the prescriber sets the final schedule.

Ibuprofen should be used with caution during pregnancy, especially in the third trimester, because it may affect fetal cardiovascular development and reduce amniotic fluid. While short‑term use in early pregnancy may be considered, any use during pregnancy or while breastfeeding must be discussed with a qualified healthcare provider.

To order Ibuned, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and the necessary import documentation.

Ibuned (ibuprofen) shares the core NSAID properties of analgesia, antipyresis, and anti‑inflammation with agents such as naproxen or diclofenac. Compared with some longer‑acting NSAIDs, ibuprofen has a relatively short half‑life, allowing flexible dosing but may require more frequent administration. Its safety profile is well‑characterized, though gastrointestinal and renal risks are similar across the class.

Ibuned should be stored at room temperature, below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight, and excessive heat. Keep it out of reach of children and do not use it after the expiration date printed on the label.

Ibuned is taken orally with a full glass of water. It may be taken with or without food; however, taking it with food or milk can help reduce possible stomach irritation. Swallow tablets or capsules whole; do not crush or chew unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulcer perforation, especially in patients with a history of ulcers or who use anticoagulants. Renal impairment can occur, particularly in those with pre‑existing kidney disease or dehydration. Severe allergic reactions such as anaphylaxis, as well as cardiovascular events like heart attack or stroke, are also important warnings.

Ibuned should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active peptic ulcer disease, severe heart failure, or significant renal or hepatic impairment. It is also contraindicated in the third trimester of pregnancy and in patients taking certain anticoagulants or other drugs that markedly increase bleeding risk without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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