Product image of Ibupas (Ibuprofen) supplied by GNH India

Ibupas

Active Ingredient:
Ibuprofen
Origin:
EU

Ibupas (Ibuprofen)

Ibuprofen, the active ingredient in Ibupas, is a nonsteroidal anti-inflammatory drug presented as a topical gel for cutaneous use. It is used to relieve pain and reduce inflammation in adults and adolescents with musculoskeletal discomfort.

GNH India supplies Ibupas as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand.

Manufacturer / TM Owner

Alfasigma S.P.A.

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Indications & Clinical Uses

Ibupas (ibuprofen) acts on inflammatory pathways to provide analgesic and anti‑inflammatory effects.

  • Musculoskeletal pain: alleviates aches and stiffness in muscles, tendons and joints.
  • Minor joint inflammation: reduces swelling and discomfort in conditions such as osteoarthritis.
  • Acute soft‑tissue injury: eases pain and inflammation from sprains, strains or bruises.

How It Works

  • Ibuprofen reversibly inhibits cyclooxygenase (COX‑1 and COX‑2) enzymes, decreasing the synthesis of prostaglandins that mediate pain, fever and inflammation. By limiting prostaglandin production at the site of application, the topical formulation reduces local sensitization of nociceptors and diminishes inflammatory swelling.

Side Effects

Topical ibuprofen may cause local and systemic adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Skin irritation: redness or mild burning at the application site.
  • Itching: localized pruritus.
  • Dryness: peeling or flaking of the skin.
  • Stinging sensation: transient sharp feeling upon application.

Serious or Rare Side Effects

  • Allergic dermatitis: widespread rash, swelling or hives.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Systemic toxicity: gastrointestinal ulceration or bleeding if absorbed in large amounts.
  • Renal impairment: reduced kidney function in susceptible individuals.

Precautions & Warnings

Before using Ibupas, consider the following safety measures.

  • Assess medical history: confirm no known hypersensitivity to ibuprofen or other NSAIDs.
  • Avoid broken skin: do not apply on open wounds, cuts or irritated areas.
  • Limit duration: use only for the recommended short‑term period, typically up to 7 days.
  • Monitor gastrointestinal symptoms: watch for stomach pain, nausea or bleeding.
  • Caution in cardiovascular disease: evaluate risk before use in patients with heart conditions.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Ibupas may interact with other medicines; some combinations should be avoided while others require monitoring.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: heightened ulcer risk.
  • Lithium: elevated lithium serum levels.
  • Methotrexate: enhanced methotrexate toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in renal function.
  • Diuretics: potential for decreased kidney perfusion.
  • Selective serotonin reuptake inhibitors: modest increase in bleeding risk.

Frequently Asked Questions

Ibupas is a topical ibuprofen formulation indicated for the relief of mild to moderate pain and reduction of inflammation associated with musculoskeletal conditions, minor joint discomfort, and acute soft‑tissue injuries such as sprains or strains.

Ibuprofen blocks the cyclooxygenase enzymes COX‑1 and COX‑2, which are required for prostaglandin production. By lowering prostaglandin levels at the site of application, it diminishes the sensitisation of pain receptors and curtails the inflammatory response.

The appropriate amount of Ibupas is determined by the prescribing health‑care professional based on the individual’s condition, age, and treatment duration. Patients should follow the prescriber’s instructions and the product label for application frequency.

Safety data for topical ibuprofen in pregnancy and lactation are limited. Health‑care providers usually weigh potential benefits against risks before recommending use. Women who are pregnant, planning pregnancy, or breastfeeding should consult their physician before applying Ibupas.

To request Ibupas, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibupas contains ibuprofen, a well‑studied NSAID, and offers comparable analgesic and anti‑inflammatory efficacy to other topical NSAID gels such as diclofenac. Choice often depends on clinician preference, patient tolerance, and specific formulation characteristics like excipients or gel viscosity.

Store Ibupas at room temperature, preferably below 25 °C, in its original packaging. Protect the container from moisture, direct sunlight and extreme temperatures to maintain product stability and potency.

Apply a thin layer of the gel to clean, dry skin over the affected area, gently rubbing it in until absorbed. Follow the prescriber’s recommended frequency, usually not exceeding the number of applications indicated on the label.

Serious adverse events include severe allergic skin reactions such as Stevens‑Johnson syndrome, systemic toxicity leading to gastrointestinal bleeding or ulceration, and renal impairment, especially in patients with pre‑existing kidney disease or those using other nephrotoxic agents.

Individuals with known hypersensitivity to ibuprofen or any NSAID, those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or who are using anticoagulants without medical supervision should avoid using Ibupas.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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