Product image of Ibuprex (Ibuprofen) supplied by GNH India

Ibuprex

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprex (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprex, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It treats mild to moderate pain, fever and inflammatory conditions such as arthritis in adults and children when appropriate.
GNH India supplies Ibuprex as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Olimp Laboratories Sp. Z O.O.

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Indications & Clinical Uses

Ibuprex, an NSAID, works by reducing inflammation and pain in several common conditions.

  • Pain (mild to moderate): alleviates headaches, dental pain, musculoskeletal aches and other everyday discomforts.
  • Fever: helps lower elevated body temperature associated with infections or inflammatory states.
  • Arthritis (inflammatory joint conditions): reduces pain, swelling and stiffness in osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which decreases the synthesis of prostaglandins involved in inflammation, pain signaling and fever generation, thereby providing analgesic, antipyretic and anti‑inflammatory actions.

Side Effects

Adverse reactions may occur with ibuprofen use and vary in frequency.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia or abdominal discomfort.
  • Headache: mild to moderate intensity.
  • Dizziness or light‑headedness.
  • Rash or mild skin irritation.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Acute renal impairment or worsening of chronic kidney disease.
  • Severe allergic reactions such as anaphylaxis.
  • Elevated liver enzymes or hepatic injury.
  • Cardiovascular events including thrombotic complications.

Precautions & Warnings

Before using Ibuprex, consider the following safety measures.

  • Assess renal function: adjust or avoid use in patients with significant kidney impairment.
  • Monitor gastrointestinal risk: avoid in individuals with a history of ulcers or gastrointestinal bleeding.
  • Use cautiously in cardiovascular disease: be aware of potential increased thrombotic risk.
  • Avoid in late pregnancy: consult an obstetrician before use during the third trimester.
  • Store at room temperature: keep in the original packaging, protect from moisture and heat.

Avoid Interactions

Ibuprex can interact with other medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or aspirin: heightened gastrointestinal toxicity.
  • Corticosteroids: synergistic risk of ulceration and bleeding.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or diuretics: possible reduction in renal function.
  • Lithium or methotrexate: ibuprofen may raise serum levels, requiring monitoring.

Frequently Asked Questions

Ibuprex contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, reduce fever, and manage inflammatory conditions such as osteoarthritis and rheumatoid arthritis. It works across a range of everyday discomforts and inflammatory disorders.

Ibuprofen blocks the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for producing prostaglandins. By lowering prostaglandin levels, it reduces inflammation, diminishes pain signals, and helps bring down elevated body temperature.

The appropriate dose of Ibuprex is determined by a qualified prescriber based on the patient’s age, weight, medical condition and response to therapy. Patients should follow the specific dosing instructions provided by their healthcare professional.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and individual risk factors. It is generally avoided in the third trimester and used only when clearly needed in earlier stages. Breastfeeding mothers should consult a healthcare provider before use.

To request Ibuprex, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibuprex (ibuprofen) offers a balance of analgesic, antipyretic and anti‑inflammatory effects similar to other NSAIDs such as naproxen or diclofenac. Compared with some alternatives, ibuprofen has a relatively short half‑life, which may require more frequent dosing but also allows quicker clearance if side effects arise.

Ibuprex should be stored at room temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, direct sunlight and excessive heat to maintain stability and potency.

Ibuprex is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food may reduce gastrointestinal discomfort for some patients.

Serious risks include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis, acute kidney injury, and increased cardiovascular events like heart attack or stroke, especially with high‑dose or prolonged use.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or in the third trimester of pregnancy should avoid using Ibuprex unless directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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