Product image of Ibufén (Ibuprofen) supplied by GNH India

Ibufén

Active Ingredient:
Ibuprofen
Origin:
EU

Ibufén (Ibuprofen)

Ibuprofen, the active ingredient in Ibufén, is a nonsteroidal anti-inflammatory drug presented as an oral dosage form for oral use. It treats mild to moderate pain, fever, and inflammatory conditions such as arthritis in adults and children as appropriate.

GNH India supplies Ibufén as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratorios Cinfa S.A.

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Indications & Clinical Uses

Ibuprofen is an NSAID that reduces inflammation and pain by inhibiting cyclooxygenase enzymes.

  • Mild to moderate pain: provides analgesic relief for headache, dental pain, musculoskeletal discomfort, and similar conditions.
  • Fever: lowers elevated body temperature associated with infections or inflammatory states.
  • Inflammatory arthritis: decreases joint swelling and pain in rheumatoid arthritis and osteoarthritis.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. Reduced prostaglandin synthesis diminishes inflammation, pain signaling, and fever generation at the site of tissue injury or infection.

Side Effects

Adverse reactions may range from mild gastrointestinal discomfort to rare but serious systemic events.

Common Side Effects

  • Nausea: mild stomach upset after ingestion.
  • Dyspepsia: indigestion or heartburn.
  • Headache: transient cranial discomfort.
  • Dizziness: light‑headed sensation.
  • Rash: mild skin irritation.
  • Diarrhea: loose stools.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: visible blood in stool or vomiting blood.
  • Peptic ulcer perforation: severe abdominal pain requiring emergency care.
  • Renal impairment: reduced kidney function, especially in dehydration.
  • Severe allergic reactions: anaphylaxis with swelling, hives, or breathing difficulty.
  • Hepatic injury: abnormal liver enzymes or jaundice.
  • Cardiovascular events: increased risk of heart attack or stroke in high‑risk patients.

Precautions & Warnings

Before using Ibufén, consider the following safety measures.

  • Assess gastrointestinal risk: evaluate history of ulcers or bleeding before use.
  • Monitor renal function: avoid in patients with severe kidney disease or dehydration.
  • Avoid concomitant anticoagulants: increased bleeding risk when combined with warfarin or similar agents.
  • Use lowest effective dose: limit duration to reduce adverse events.
  • Store at ambient temperature: keep in original container, protect from moisture and heat.

Avoid Interactions

Ibuprofen can interact with several medicines; some combinations should be avoided while others require monitoring.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • Selective serotonin reuptake inhibitors (SSRIs): increased gastrointestinal bleeding.
  • Lithium: ibuprofen may raise lithium serum levels.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: may reduce renal function when used together.
  • Diuretics: potential for reduced kidney perfusion and electrolyte imbalance.

Frequently Asked Questions

Ibufén contains ibuprofen, an NSAID indicated for relief of mild to moderate pain, reduction of fever, and management of inflammatory conditions such as rheumatoid arthritis and osteoarthritis. It is commonly prescribed for headaches, dental pain, musculoskeletal discomfort, and febrile illnesses.

Ibuprofen works by non‑selectively blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin levels, it reduces inflammation, diminishes pain signaling, and helps lower elevated body temperature.

The appropriate dose of Ibufén is determined by the prescribing healthcare professional based on the patient’s age, weight, condition being treated, and overall health status. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Safety of ibuprofen in pregnancy and lactation depends on the trimester and individual risk factors. Generally, ibuprofen is avoided in the third trimester because of potential fetal complications, and caution is advised during the first two trimesters. Breastfeeding mothers should consult their physician before use.

To place an order, submit an enquiry on the Ibufén product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Ibufén (ibuprofen) and naproxen belong to the same NSAID class but differ in duration of action and dosing frequency. Ibuprofen typically requires multiple daily doses, while naproxen has a longer half‑life allowing twice‑daily dosing. Both share similar efficacy for pain and inflammation, yet individual tolerability and drug‑interaction profiles may guide selection.

Ibufén should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the container tightly closed and out of reach of children. No refrigeration is required for this oral formulation.

Ibufén is taken orally, usually with a full glass of water. It may be taken with food or milk to lessen stomach irritation, but it can also be taken on an empty stomach if tolerated. The exact administration schedule is set by the prescriber.

Serious risks include gastrointestinal bleeding or ulcer perforation, especially in patients with a history of ulcers or who use anticoagulants. Renal impairment, severe allergic reactions such as anaphylaxis, and increased cardiovascular events (heart attack or stroke) are also important concerns that require prompt medical attention.

Ibufén should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, patients with severe renal or hepatic impairment, and anyone in the third trimester of pregnancy. Consultation with a healthcare provider is essential before use in these groups.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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