Product image of Ibufén Infantil (Ibuprofen) supplied by GNH India

Ibufén Infantil

Active Ingredient:
Ibuprofen
Origin:
EU

Ibufén Infantil (Ibuprofen)

Ibuprofen, the active ingredient in Ibufén Infantil, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral suspension for pediatric use. It provides analgesic, antipyretic, and anti‑inflammatory effects to relieve pain, reduce fever, and manage inflammation in children. It is formulated for easy dosing in children and is available over the counter in many EU markets.

GNH India supplies Ibufén Infantil as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to stringent quality standards and regulatory requirements.

Manufacturer / TM Owner

Laboratorios Cinfa S.A.

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Indications & Clinical Uses

  • Ibuprofen acts as an NSAID to reduce pain, fever, and inflammation in pediatric patients.
  • Pain in children: provides relief from mild to moderate pain such as headache, toothache or sore muscles.
  • Fever in children: helps lower elevated body temperature associated with common infections.
  • Inflammation in pediatric patients: decreases swelling and discomfort in conditions like minor injuries or musculoskeletal strain.

How It Works

  • Ibuprofen reversibly inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. Reduced prostaglandin synthesis leads to diminished inflammation, lower pain signaling, and an effect on the hypothalamic heat‑regulation center that reduces fever. By blocking these pathways, ibuprofen also reduces platelet aggregation and gastric mucosal protection, which contributes to its safety profile when used at recommended pediatric doses.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Stomach upset: nausea, abdominal discomfort or dyspepsia.
  • Diarrhea: loose stools that may occur during treatment.
  • Rash: mild skin redness or itching.

Serious or Rare Side Effects

  • Allergic reactions: hives, swelling, or anaphylaxis.
  • Gastrointestinal bleeding: vomiting blood or black stools.
  • Kidney impairment: reduced urine output or swelling.

Precautions & Warnings

  • When using Ibufén Infantil, consider the following precautions to ensure safe administration in children.
  • Dose adjustment: follow prescriber instructions based on age and weight.
  • Allergy: avoid if the child has known hypersensitivity to ibuprofen or other NSAIDs.
  • Gastrointestinal: monitor for stomach pain, ulcers or bleeding, especially with prolonged use.
  • Renal: use cautiously in children with dehydration, kidney disease or concurrent nephrotoxic drugs.
  • Bleeding risk: be careful when combined with anticoagulants or antiplatelet agents.
  • Store at ambient temperature: keep below 25 °C in the original container, protected from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medicines; some require avoidance while others need monitoring.

Major Interactions (Avoid)

  • Aspirin in children: increases risk of Reye’s syndrome.
  • Anticoagulants (warfarin, heparin): may enhance bleeding tendency.
  • Lithium: ibuprofen can raise lithium serum levels.
  • Methotrexate: increased toxicity risk.
  • ACE inhibitors or ARBs: may reduce renal function.

Moderate Interactions (Monitor Closely)

  • Diuretics: possible reduction in renal perfusion.
  • Corticosteroids: heightened risk of gastrointestinal ulceration.
  • SSRIs: modest increase in bleeding risk.
  • Antihypertensives: ibuprofen may diminish blood‑pressure‑lowering effect.
  • Other NSAIDs: additive toxicity.

Frequently Asked Questions

Ibufén Infantil is an oral ibuprofen suspension indicated for the relief of mild to moderate pain, reduction of fever, and control of inflammation in pediatric patients. It is commonly used for headaches, toothaches, post‑vaccination fever, and minor injuries in children.

Ibuprofen works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the production of prostaglandins. Lower prostaglandin levels decrease pain signaling, lower body temperature in the hypothalamus, and diminish inflammatory swelling.

The appropriate dose of Ibufén Infantil is determined by the prescribing healthcare professional based on the child’s age, weight, and clinical condition. Caregivers should follow the exact instructions provided on the prescription label and not exceed the recommended amount.

Safety data for ibuprofen in pregnancy are limited, and it is generally avoided, especially in the third trimester. During breastfeeding, ibuprofen passes into milk in small amounts; a healthcare provider should evaluate the risk‑benefit before use.

To request Ibufén Infantil, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Compared with acetaminophen, ibuprofen provides both analgesic and anti‑inflammatory effects and may be more effective for pain associated with swelling. However, ibuprofen carries a higher risk of gastrointestinal irritation, so the choice depends on the child’s medical history and the clinician’s judgment.

Store the suspension at ambient temperature, preferably below 25 °C, in its original container. Keep it away from moisture, direct sunlight and children’s reach. Do not freeze the product.

Ibufén Infantil is given orally, usually using a calibrated dosing syringe or cup. The dose is measured according to the prescriber’s instructions and administered with or without food, as directed.

The most serious risks include severe allergic reactions such as anaphylaxis, gastrointestinal bleeding or ulceration, and kidney impairment, especially in dehydrated children or those receiving other nephrotoxic drugs. Immediate medical attention is required if these occur.

Children with a known hypersensitivity to ibuprofen or any other NSAID, those with active gastrointestinal bleeding, severe renal or hepatic impairment, or those who have experienced Reye’s syndrome should not be given Ibufén Infantil. Consultation with a healthcare professional is essential.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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